Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I

scientific article published on May 1, 1993

Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.121.3.679
P953full work available at URLhttps://rupress.org/jcb/article-pdf/121/3/679/1256517/679.pdf
https://europepmc.org/articles/PMC2119570
https://europepmc.org/articles/PMC2119570?pdf=render
https://rupress.org/jcb/article-pdf/121/3/679/1474008/679.pdf
P932PMC publication ID2119570
P698PubMed publication ID7683690
P5875ResearchGate publication ID277465785

P2093author name stringD. R. Clemmons
J. I. Jones
C. Camacho-Hubner
W. H. Busby
A. Gockerman
P2860cites workNovel regulators of bone formation: molecular clones and activitiesQ24297338
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA'sQ24339580
Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-betaQ24679265
Recent developments in the cell biology of basic fibroblast growth factorQ24679568
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130Q28279735
Purification of a 31,000-dalton insulin-like growth factor binding protein from human amniotic fluid. Isolation of two forms with different biologic actionsQ28285933
Negative regulation of transforming growth factor-beta by the proteoglycan decorinQ28292224
Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiationQ28296150
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptorQ29616189
Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factorQ33784803
The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrixQ33919776
Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I.Q34578087
Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrixQ34613112
An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I.Q34623199
Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cellsQ35580262
A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membraneQ35818217
Metabolism of receptor-bound and matrix-bound basic fibroblast growth factor by bovine capillary endothelial cellsQ36219208
Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradationQ36219245
A dual receptor system is required for basic fibroblast growth factor activityQ36428185
Cytokines in contextQ36529819
Insulin-like growth factor binding proteins: roles in regulating IGF physiologyQ36670514
Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-IQ37583391
Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like moleculesQ38345199
Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF I-induced stimulation of osteoblasts: control of IGF signalling to bone cells by IGFBP-3-specific proteolysis?Q41668778
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptorQ41687095
Three Distinct Forms of Insulin-Like Growth Factor Binding Proteins are Released by Decidual Cells in Culture*Q42465706
Solution structure of human plasma fibronectin as a function of NaCl concentration determined by small-angle X-ray scatteringQ42646692
Radioimmunoassay of a 26,000-dalton plasma insulin-like growth factor-binding protein: control by nutritional variables.Q51623886
Structural requirements for the extracellular interaction of plasminogen activator inhibitor 1 with endothelial cell matrix-associated vitronectinQ52162407
Cloning and sequence determination of bovine insulin-like growth factor binding protein-2 (IGFBP-2): comparison of its structural and functional properties with IGFBP-1Q53985452
Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesisQ59067534
Insulin-like growth factor (IGF) binding to cell monolayers is directly modulated by the addition of IGF-binding proteinsQ67695232
Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretionQ67897224
Identification of somatomedin/insulin-like growth factor immunoreactive cells in the human fetusQ68191125
Primary structure of human skeletal growth factor: homology with human insulin-like growth factor-IIQ68431796
Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding proteins and competitive binding studiesQ68962393
Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetusQ68975709
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin geneQ69344366
Immunological distribution of one form of insulin-like growth factor (IGF)-binding protein and IGF peptides in human fetal tissuesQ69354523
Proteoglycans in cell regulationQ69522593
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectextracellular matrixQ193825
preproinsulinQ7240673
P304page(s)679-687
P577publication date1993-05-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleExtracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I
P478volume121

Reverse relations

cites work (P2860)
Q714340721 alpha,25-dihydroxyvitamin D3 increases IGF binding protein-5 expression in cultured osteoblasts
Q93089571A High-Throughput Workflow to Study Remodeling of Extracellular Matrix-Based Microtissues
Q64925304A systems perspective of heterocellular signaling.
Q38624157Advanced Strategies for Articular Cartilage Defect Repair
Q36826856Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.
Q71965133Altered IGFBP5 gene expression in the cerebellar external germinal layer of weaver mutant mice
Q40838442Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage
Q41450482Apoptosis, tumour invasion and prostate cancer
Q42455214Axon initiation and growth cone turning on bound protein gradients.
Q34667976B-cell lymphopoiesis is regulated by cathepsin L.
Q36793323Basal lamina and other extracellular matrix produced by bovine granulosa cells in anchorage-independent culture
Q47912563Binding of IGF-I to preimplantation rabbit embryos and their coats
Q36904666Binding of insulin-like growth factor (IGF)-binding protein-5 to smooth-muscle cell extracellular matrix is a major determinant of the cellular response to IGF-I
Q37388231Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts
Q42413507Cartilage constructs engineered from chondrocytes overexpressing IGF-I improve the repair of osteochondral defects in a rabbit model.
Q26751449Cell surface receptors for CCN proteins
Q33607372Cellular actions of insulin-like growth factor binding proteins
Q33644573Characteristics of skeletal muscle in mdx mutant mice
Q62267736Characterization of insulin-like growth factor binding proteins and regulation of IGFBP3 in human mesangial cells
Q37409389Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels
Q35731942Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid.
Q47161268Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis
Q44440538Control of Insulin-Like Growth Factor Binding Protein-5 Protease Synthesis and Secretion by Human Fibroblasts and Porcine Aortic Smooth Muscle Cells
Q64463826Control of mammary involution by insulin-like growth factor binding proteins: role of prolactin
Q49108791Coordinate IGF-I and IGFBP5 gene expression in perinatal rat brain after hypoxia-ischemia
Q38359116Cortisol inhibits the synthesis of insulin-like growth factor-binding protein-5 in bone cell cultures by transcriptional mechanisms
Q42490470Cultured incisors display major modifications in basal lamina deposition without further effect on odontoblast differentiation
Q38968053Customized biomaterials to augment chondrocyte gene therapy
Q74308159Cyclic AMP agonists increase levels of insulin-like growth factor (IGF) binding protein-6 in PC12 rat phaeochromocytoma cells
Q42491727Damage control mechanisms in articular cartilage: the role of the insulin-like growth factor I axis
Q34367785Decreased caveolin-1 levels contribute to fibrosis and deposition of extracellular IGFBP-5.
Q33847396Development and postnatal regulation of adult myoblasts
Q46266168Development of embryonic chick insulin cells in culture: beneficial effects of serum-free medium, raised nutrients, and biomatrix
Q47921690Differential expression and biological effects of insulin-like growth factor-binding protein-4 and -5 in vascular smooth muscle cells
Q38299912Diminished expression of insulin-like growth factor (IGF) binding protein-5 and activation of IGF-I-mediated autocrine growth in simian virus 40-transformed human fibroblasts
Q37418923Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions
Q35971304Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy
Q36459287E-peptides control bioavailability of IGF-1.
Q59336634Effect of diets supplemented with linseed alone or combined with vitamin E and selenium or with plant extracts, on transcriptome in growing-finishing Italian Large White pigs
Q36964578Effects of insulin-like growth factor binding proteins in bone -- a matter of cell and site
Q36714137Effects of systemic and local administration of recombinant human IGF-I (rhIGF-I) on de novo bone formation in an aged mouse model
Q41440987Enhanced expression of dihydrofolate reductase by bovine kidney epithelial cells results in altered cell morphology, IGF‐I responsiveness, and IGF binding protein‐3 expression
Q33964969Epigenetic signals during odontoblast differentiation
Q33866151Estrogen Receptor-β and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer.
Q36001447Evidence that IGF-binding protein-5 functions as a growth factor
Q30384833Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.
Q42457781Expression and localization of insulin-like growth factor-1 in normal and post-burn hypertrophic scar tissue in human
Q71956626Expression of IGF-I, IGF-I receptor and IGF binding proteins-1, -2, -3, -4 and -5 in human atherectomy specimens
Q48543210Expression of IGF-II, IGFBP-2, -5, and -6 in meningiomas with different brain invasiveness
Q51131202Expression of insulin-like growth factor and binding protein genes during nephrogenesis.
Q38340992Expression of insulin-like growth factor-binding protein messenger RNAs in developing rat oligodendrocytes and astrocytes
Q33744976Extracellular matrix remodelling and cellular differentiation
Q35216162Fibrotic response in fibroblasts from congenital disorders of glycosylation
Q52192373Gene expression of the insulin-like growth factor system during mouse kidney development.
Q28215493Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis
Q41693134General aspects of insulin-like growth factor binding proteins
Q33975045Genetics, chemistry, and function of the IGF/IGFBP system
Q42727595Glucose Regulation of Thrombospondin and Its Role in the Modulation of Smooth Muscle Cell Proliferation
Q77360084Glycosaminoglycan-promoted muscle reinnervation and insulin-like growth factor-I levels are affected by anti-growth hormone-releasing hormone exposure
Q60649902Glycosaminoglycans boost insulin-like growth factor-I-promoted neuroprotection: blockade of motor neuron death in the wobbler mouse
Q73561752Glycosaminoglycans treatment increases IGF-I muscle levels and counteracts motor neuron death: A novel nonanticoagulant action
Q37147591Growth hormone, insulin-like growth factors, and the skeleton
Q36235477High affinity immunoreactive FGF receptors in the extracellular matrix of vascular endothelial cells--implications for the modulation of FGF-2.
Q54334425High force development augments skeletal muscle signalling in resistance exercise modes equalized for time under tension.
Q41508533Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy
Q34982361IGF binding protein-4 is required for the growth effects of glucagon-like peptide-2 in murine intestine
Q37334106IGF binding proteins (IGFBPs) and regulation of breast cancer biology.
Q40490283IGF binding proteins and their functions
Q73793423IGF-1 stimulates synthesis of undersulfated proteoglycans and of hyaluronic acid by peritubular cells from immature rat testis
Q40710505IGF-I and TGF-beta1 have distinct effects on phenotype and proliferation of intestinal fibroblasts
Q40948182IGF-I and retinoic acid regulate the distribution pattern of IGFBPs synthesized by the canine mammary tumor cell line CMT-U335.
Q44833653IGF-I increases IGFBP-5 and collagen alpha1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cells
Q35836632IGFBP ratio confers resistance to IGF targeting and correlates with increased invasion and poor outcome in breast tumors
Q34740473IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells
Q35672107IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF.
Q40727399Immunohistochemical pattern of insulin-like growth factor (IGF) I, IGF II and IGF binding proteins 1 to 6 in carcinoma in situ of the testis
Q34030616In vitro studies of insulin-like growth factor I and bone
Q36095787Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism
Q40923668Induction of insulin-like growth factor binding protein expression by ICI 182,780 in a tamoxifen-resistant human breast cancer cell line
Q43937867Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis
Q38574758Inhibition of proliferation in 8-week-old mdx mouse muscle fibroblasts in vitro
Q90479283Insulin-Like Growth Factor Binding Protein-5 in Physiology and Disease
Q64966018Insulin-Like Growth Factor-1 Signaling in Lung Development and Inflammatory Lung Diseases.
Q24316404Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit
Q53557500Insulin-like growth factor binding protein (IGFBP)-mediated hair cell survival on the mouse utricle exposed to neomycin: the roles of IGFBP-4 and IGFBP-5.
Q31807473Insulin-like growth factor binding protein 5 and type-1 insulin-like growth factor receptor are differentially regulated during apoptosis in cerebellar granule cells
Q35114599Insulin-like growth factor binding protein proteolysis
Q24294434Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions
Q36236830Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism
Q35083605Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition
Q41489957Insulin-like growth factor binding proteins and their role in controlling IGF actions
Q33904097Insulin-like growth factor binding proteins: IGF-dependent and -independent effects in the mammary gland
Q30417447Insulin-like growth factor binding proteins: a structural perspective
Q41058586Insulin-like growth factor receptors and binding proteins
Q37382009Insulin-like growth factor system abnormalities in hepatitis C-associated osteosclerosis. Potential insights into increasing bone mass in adults
Q38361431Insulin-like growth factor-I (IGF-I) regulates IGF-binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells
Q36417183Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis
Q37733826Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: roles in skeletal muscle growth and differentiation
Q41056187Insulin-like growth factors and inflammatory bowel disease
Q24800144Insulin-like growth factors and insulin-like growth factor binding proteins in mammary gland function
Q34767957Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth
Q38317027Interactions between bcl-2 and the IGF system control apoptosis in the developing mouse brain
Q46769458Interleukin-11 inhibits expression of insulin-like growth factor binding protein-5 mRNA in decidualizing human endometrial stromal cells
Q36163374Investigating endogenous peptides and peptidases using peptidomics
Q37695701Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor
Q42436682Localization of insulin-like growth factor binding protein-2 in chondrocytes of bovine articular cartilage
Q60169586Localization of mRNAs for insulin-like growth factor binding proteins 1 to 6 in rat kidney
Q40159420Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.
Q28618638Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures
Q34195881Matrix production and remodeling as therapeutic targets for uterine leiomyoma
Q38293068Mechanical regulation of IGF-I and IGF-binding protein gene transcription in bladder smooth muscle cells
Q39689738Mechanistic investigations into interactions between IGF-I and IGFBPs and their impact on facilitating cell migration on vitronectin.
Q42799469Membrane-associated insulin-like growth factor-binding protein-3 inhibits insulin-like growth factor-I-induced insulin-like growth factor-I receptor signaling in ishikawa endometrial cancer cells
Q38328312MiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells
Q37257924Modulation of GH/IGF-1 axis: potential strategies to counteract sarcopenia in older adults
Q38128702Molecular mechanisms of the cartilage-specific microRNA-140 in osteoarthritis.
Q36955081Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer
Q28566855Muscle reinnervation and IGF-I synthesis are affected by exposure to heparin: an effect partially antagonized by anti-growth hormone-releasing hormone
Q42450805Muscle reinnervation following neonatal nerve crush. Interactive effects of glycosaminoglycans and insulin-like growth factor-I.
Q44068358Mutation of the RGD sequence does not affect plasma membrane association and growth inhibitory effects of elevated IGFBP-2 in vivo
Q38647615NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis
Q73443629NMR 15N relaxation of the insulin-like growth factor (IGF)-binding domain of IGF binding protein-5 (IGFBP-5) determined free in solution and in complex with IGF-II
Q50086407Nephrotoxicity Induced by Cisplatin Intake in Experimental Rats and Therapeutic Approach of Using Mesenchymal Stem Cells and Spironolactone
Q46842475Neural and head induction by insulin-like growth factor signals
Q58788300Neurite Growth and Polarization on Vitronectin Substrate after in Vitro Trauma is not Enhanced after IGF Treatment
Q37254131Nuclear factor I transcription factors regulate IGF binding protein 5 gene transcription in human osteoblasts
Q28616606O-glycosylation of insulin-like growth factor (IGF) binding protein-6 maintains high IGF-II binding affinity by decreasing binding to glycosaminoglycans and susceptibility to proteolysis
Q35755050Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes
Q52127494Partial purification and characterization of proteins with growth promoting activities from ovine mammary gland secretions.
Q47331410Potentiating role of IGFBP-2 on IGF-II-stimulated alkaline phosphatase activity in differentiating osteoblasts
Q44483053Production of insulin-like growth factor binding-proteins by bovine adrenomedullary cells: differential regulation by IGF-I and dexamethasone
Q37375061Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.
Q34362776Proteoglycans: pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland
Q42739074Quantitative characterization of binding of small molecules to extracellular matrix
Q33184835Regulation of IGFBP-5 expression during tumourigenesis and differentiation of oral keratinocytes
Q77608195Regulation of insulin-like growth factors I and II and their binding proteins in human bone marrow stromal cells by dexamethasone
Q30931885Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes
Q81065549Regulatory Actions of Insulin-like Growth Factor-binding Proteins
Q44660487Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts
Q37322147Role of insulin-like growth factor binding proteins in mammary gland development
Q33853206Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis
Q36234276Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4.
Q36782493Role of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress
Q36111179Roles of insulin-like growth factor (IGF) binding proteins in regulating IGF actions
Q28069429Roles of microRNA and signaling pathway in osteoarthritis pathogenesis
Q37123969Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism
Q41250241Serum factors inhibit melanoma cell surface expression of type I and type II IGF receptors
Q38295651Skeletal growth factors regulate the synthesis of insulin-like growth factor binding protein-5 in bone cell cultures
Q47875941Spaceflight modulates insulin-like growth factor binding proteins and glucocorticoid receptor in osteoblasts
Q24533385Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions
Q22253898Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions
Q36233928Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression
Q88936916The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate
Q92842183The Role of Gene Therapy in Cartilage Repair
Q90267521The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle
Q36940050The extracellular matrix in multiple sclerosis pathology
Q38327469The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells
Q42066582The pro-fibrotic factor IGFBP-5 induces lung fibroblast and mononuclear cell migration
Q41175229The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action
Q40835429Tissue transglutaminase facilitates the polymerization of insulin-like growth factor-binding protein-1 (IGFBP-1) and leads to loss of IGFBP-1's ability to inhibit insulin-like growth factor-I-stimulated protein synthesis
Q24310632Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression
Q33608667Transcriptional regulation of the IGF signaling pathway by amino acids and insulin-like growth factors during myogenesis in Atlantic salmon
Q47685883Use of differential subtraction method to identify genes that characterize the phenotype of cultured rheumatoid arthritis synoviocytes

Search more.