Customized biomaterials to augment chondrocyte gene therapy

scientific article

Customized biomaterials to augment chondrocyte gene therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.ACTBIO.2017.02.008
P698PubMed publication ID28185909

P2093author name stringLawrence J Bonassar
Izath Nizeet Aguilar
Shuiliang Shi
Stephen Trippel
P2860cites workStructure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactionsQ24533385
The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5Q27633115
Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging ratsQ28569577
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophyQ30545559
Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transferQ33606440
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's diseaseQ33726762
Tissue engineering via local gene deliveryQ34042830
Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfateQ34367377
Biomaterials in the repair of sports injuriesQ84603765
Binding and release characteristics of insulin-like growth factor-1 from a collagen-glycosaminoglycan scaffoldQ34414870
Plasmid-encapsulated polyethylene glycol-grafted polyethylenimine nanoparticles for gene delivery into rat mesenchymal stem cellsQ34956388
Fluorometric assay of DNA in cartilage explants using Hoechst 33258.Q35124134
Osteoarthritis gene therapyQ35629588
IGF-I is a matter of heartQ36088842
Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-IQ36232491
Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injuryQ37679296
Advances and challenges in gene-based approaches for osteoarthritisQ38134331
Presentation of BMP-2 mimicking peptides in 3D hydrogels directs cell fate commitment in osteoblasts and mesenchymal stem cells.Q39277375
Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axisQ39676689
Comparison of Efficacy of Endogenous and Exogenous IGF-I in Stimulating Matrix Production in Neonatal and Mature Chondrocytes.Q40479463
Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination.Q40792686
Alginate hydrogels as synthetic extracellular matrix materialsQ40978578
Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseasesQ41553648
Effect of transfection strategy on growth factor overexpression by articular chondrocytesQ41846147
Effect of media mixing on ECM assembly and mechanical properties of anatomically-shaped tissue engineered meniscusQ42227683
Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approachQ42438194
The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I.Q43595017
Exogenous insulin-like growth factor-I stimulates an autoinductive IGF-I autocrine/paracrine response in chondrocytesQ43595031
Gene mediated insulin-like growth factor-I delivery to the synoviumQ43741092
Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell linesQ43837302
Menisci are efficiently transduced by recombinant adeno-associated virus vectors in vitro and in vivoQ44019074
Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery systemQ44036702
The differentiation of bone marrow mesenchymal stem cells into chondrocyte-like cells on poly-L-lactic acid (PLLA) scaffoldsQ44205732
Transfection of primary chondrocytes using chitosan-pEGFP nanoparticlesQ44316476
Effect of substrate mechanics on chondrocyte adhesion to modified alginate surfacesQ44753777
Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilageQ45728584
Enhanced local delivery with reduced systemic toxicity: delivery, delivery, and delivery.Q45865369
Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine modelQ45868543
Highly efficient cell-mediated gene transfer using non-viral vectors and FuGene6: in vitro and in vivo studiesQ45871556
Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogueQ45872828
Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte functionQ45874375
Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantationQ45880338
Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I).Q45882616
Serum insulin-like growth factor I regulates brain amyloid-beta levelsQ48454367
Quantification of sulfated glycosaminoglycans in chondrocyte/alginate cultures, by use of 1,9-dimethylmethylene blue.Q50533827
Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-beta1 for chondrocytes proliferation.Q51360083
A tetracycline expression system in combination with Sox9 for cartilage tissue engineering.Q53657646
Controlled growth factor release from synthetic extracellular matricesQ59086493
Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined systemQ72724754
Anticoagulantly active heparin-like molecules from vascular tissueQ72814587
Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacingQ74148784
Controlled-release of IGF-I and TGF-beta1 in a photopolymerizing hydrogel for cartilage tissue engineeringQ77460826
Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin compositesQ78165069
Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivoQ81051748
Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescenceQ83461572
P921main subjectgene therapyQ213901
P304page(s)260-267
P577publication date2017-02-06
P1433published inActa BiomaterialiaQ4676719
P1476titleCustomized biomaterials to augment chondrocyte gene therapy
P478volume53

Reverse relations

cites work (P2860)
Q50049707Next Generation Tissue Engineering of Orthopedic Soft Tissue-to-Bone Interfaces
Q92842183The Role of Gene Therapy in Cartilage Repair

Search more.