Complement factor C3 deposition and serum resistance in isogenic capsule and lipooligosaccharide sialic acid mutants of serogroup B Neisseria meningitidis

scientific article

Complement factor C3 deposition and serum resistance in isogenic capsule and lipooligosaccharide sialic acid mutants of serogroup B Neisseria meningitidis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.65.10.4022-4029.1997
P932PMC publication ID175578
P698PubMed publication ID9317002

P2093author name stringFrank R
Frosch M
Vogel U
Müller A
Weinberger A
Atkinson JP
Köhl J
P2860cites workEffect of sialylation of lipopolysaccharide of Neisseria gonorrhoeae on recognition and complement-mediated killing by monoclonal antibodies directed against different outer-membrane antigens.Q54177285
Bactericidal but not nonbactericidal C5b-9 is associated with distinctive outer membrane proteins in Neisseria gonorrhoeae.Q54453907
Antibodies to N‐terminal peptides of gonococcal porin are bactericidal when gonococcal lipopolysaccharide is not sialylatedQ67464602
Analysis of C3 deposition and degradation on bacterial surfaces after opsonizationQ68128527
Surface-bound capsular polysaccharide of type Ia group B Streptococcus mediates C1 binding and activation of the classic complement pathwayQ68873197
Sialylation of lipopolysaccharide and loss of absorption of bactericidal antibody during conversion of gonococci to serum resistance by cytidine 5'-monophospho-N-acetyl neuraminic acidQ69245459
The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidisQ70826630
The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activationQ71071247
SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranesQ71873230
Killing of Neisseria meningitidis by human neutrophils: implications for normal and complement-deficient individualsQ28290497
Activation of the human complement alternative pathway by Listeria monocytogenes: evidence for direct binding and proteolysis of the C3 component on bacteriaQ33616834
Molecular characterization and expression in Escherichia coli of the gene complex encoding the polysaccharide capsule of Neisseria meningitidis group BQ33841587
Expression of the L8 lipopolysaccharide determinant increases the sensitivity of Neisseria meningitidis to serum bactericidal activityQ34547078
Microheterogeneity of Neisseria lipooligosaccharide: analysis of a UDP-glucose 4-epimerase mutant of Neisseria meningitidis NMB.Q35421789
Anti-Gal binds to pili of Neisseria meningitidis: the immunoglobulin A isotype blocks complement-mediated killingQ35458135
Functional characterization of a sialyltransferase-deficient mutant of Neisseria gonorrhoeaeQ35513855
Pathogenesis of Campylobacter fetus infections. Failure of encapsulated Campylobacter fetus to bind C3b explains serum and phagocytosis resistanceQ35587941
Analysis of C3 deposition and degradation on Neisseria meningitidis and Neisseria gonorrhoeae.Q35779576
Target recognition failure by the nonspecific defense system: surface constituents of pathogens interfere with the alternative pathway of complement activationQ35899072
Endogenous sialylation of the lipooligosaccharides of Neisseria meningitidisQ36145701
Prevention of C3 deposition by capsular polysaccharide is a virulence mechanism of type III group B streptococciQ36951376
Effect of exogenous sialylation of the lipooligosaccharide of Neisseria gonorrhoeae on opsonophagocytosisQ36953132
Growth of Neisseria gonorrhoeae in CMP-N-acetylneuraminic acid inhibits nonopsonic (opacity-associated outer membrane protein-mediated) interactions with human neutrophilsQ36955918
Deposition and degradation of C3 on type III group B streptococciQ36964654
Activation of the classical and alternative pathways of complement by Treponema pallidum subsp. pallidum and Treponema vincentiiQ37022345
Complement evasion by bacteria and parasitesQ39548229
Activation of the complement system by pathogenic fungiQ39820650
Sialic acid of group B Neisseria meningitidis regulates alternative complement pathway activationQ40162311
Influence of nutrient limitation and low pH on serogroup B Neisseria meningitidis capsular polysaccharide levels: correlation with virulence for miceQ40176406
Degree of antibody-independent activation of the classical complement pathway by K1 Escherichia coli differs with O antigen type and correlates with virulence of meningitis in newbornsQ40181929
Role of the capsule and the O antigen in resistance of O18:K1 Escherichia coli to complement-mediated killingQ40182051
Recognition and control of neisserial infection by antibody and complement.Q40455856
Complement deficiency states and meningococcal diseaseQ40804745
Lipo-oligosaccharides (LOS) of mucosal pathogens: molecular mimicry and host-modification of LOS.Q40825138
Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element.Q41063588
Sialylation of neisserial lipopolysaccharide: a major influence on pathogenicityQ41147868
The role of galE in the biosynthesis and function of gonococcal lipopolysaccharideQ41556908
Vaccination of patients deficient in a late complement component with tetravalent meningococcal capsular polysaccharide vaccineQ43496518
Sialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitis serogroup B are prerequisites for virulence of meningococci in the infant rat.Q43641259
C4B deficiency: a risk factor for bacteremia with encapsulated organismsQ46603538
Human IgA1 initiates complement-mediated killing of Neisseria meningitidisQ46912472
Meningococcal pilin: a glycoprotein substituted with digalactosyl 2,4-diacetamido-2,4,6-trideoxyhexoseQ48070795
Contribution of genes from the capsule gene complex (cps) to lipooligosaccharide biosynthesis and serum resistance in Neisseria meningitidis.Q48084641
Binding of mannan-binding protein to various bacterial pathogens of meningitisQ50147158
Detection of native human complement components C3 and C5 and their primary activation peptides C3a and C5a (anaphylatoxic peptides) by ELISAs with monoclonal antibodies.Q52559536
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectNeisseria meningitidisQ154625
P304page(s)4022-4029
P577publication date1997-10-01
P1433published inInfection and ImmunityQ6029193
P1476titleComplement factor C3 deposition and serum resistance in isogenic capsule and lipooligosaccharide sialic acid mutants of serogroup B Neisseria meningitidis
P478volume65

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cites work (P2860)
Q39143108A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalized modules for membrane antigens (GMMA).
Q64106983A homopolymeric adenosine tract in the promoter region of nspA influences factor H-mediated serum resistance in Neisseria meningitidis
Q36400453A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae
Q92156626Atypical, Yet Not Infrequent, Infections with Neisseria Species
Q36402993Available carbon source influences the resistance of Neisseria meningitidis against complement
Q33958765Bacterial avoidance of phagocytosis.
Q42911223Biochemical characterization of a Neisseria meningitidis polysialyltransferase reveals novel functional motifs in bacterial sialyltransferases
Q37727051Biofilm formation by the human pathogen Neisseria meningitidis
Q33768892CD46-independent binding of neisserial type IV pili and the major pilus adhesin, PilC, to human epithelial cells
Q41774048Characterization of an antibody depletion assay for analysis of bactericidal antibody specificity
Q33685515Clinical and laboratory evidence for Neisseria meningitidis biofilms
Q34796849Comparative Genomics Reveal That Host-Innate Immune Responses Influence the Clinical Prevalence of Legionella pneumophila Serogroups.
Q39667409Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence
Q39655597Complement activation and formation of the membrane attack complex on serogroup B Neisseria meningitidis in the presence or absence of serum bactericidal activity
Q38322923Decoration of Histophilus somni lipooligosaccharide with N-acetyl-5-neuraminic acid enhances bacterial binding of complement factor H and resistance to killing by serum and polymorphonuclear leukocytes
Q36422066Defining targets for complement components C4b and C3b on the pathogenic neisseriae
Q35888059Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen
Q37401428Factor H and neisserial pathogenesis
Q37191341Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18 to 20 to Neisseria gonorrhoeae porin
Q35833811Host-like carbohydrates promote bloodstream survival of Vibrio vulnificus in vivo
Q24534699Identification of a novel sialic acid transporter in Haemophilus ducreyi
Q35637385Identification of the hypervirulent lineages of Neisseria meningitidis, the ST-8 and ST-11 complexes, by using monoclonal antibodies specific to NmeDI.
Q35689380Lactate acquisition promotes successful colonization of the murine genital tract by Neisseria gonorrhoeae
Q33599918Lipooligosaccharide P(k) (Galalpha1-4Galbeta1-4Glc) epitope of moraxella catarrhalis is a factor in resistance to bactericidal activity mediated by normal human serum
Q37531325Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development
Q34376170Meningococcal disease and the complement system
Q34624357Meningococcal group W-135 and Y capsular polysaccharides paradoxically enhance activation of the alternative pathway of complement
Q35063071Molecular characterization of the interaction between sialylated Neisseria gonorrhoeae and factor H.
Q35554124Molecular mimicry of host structures by lipooligosaccharides of Neisseria meningitidis: characterization of sialylated and nonsialylated lacto-N-neotetraose (Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc) structures in lipooligosaccharides using monoclonal a
Q37523580Naturally acquired passive protective activity against Neisseria meningitidis Group C in the absence of serum bactericidal activity
Q36888510Neisseria meningitidis Polynucleotide Phosphorylase Affects Aggregation, Adhesion, and Virulence
Q41601349NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus
Q34428168Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci
Q34116680Phase variation of Campylobacter jejuni 81-176 lipooligosaccharide affects ganglioside mimicry and invasiveness in vitro
Q77566070Polysialic acid: three-dimensional structure, biosynthesis and function
Q33946852Protection by natural human immunoglobulin M antibody to meningococcal serogroup B capsular polysaccharide in the infant rat protection assay is independent of complement-mediated bacterial lysis
Q35046832Revisiting the host as a growth medium
Q41459015Role of YadA, Ail, and Lipopolysaccharide in Serum Resistance of Yersinia enterocolitica Serotype O:3.
Q34006932Role of capsule in the pathogenesis of fowl cholera caused by Pasteurella multocida serogroup A.
Q39509812Role of lipopolysaccharide sialylation in serum resistance of serogroup B and C meningococcal disease isolates.
Q34071034Sialic acid involved in hypermucoviscosity phenotype of Klebsiella pneumoniae and associated with resistance to neutrophil phagocytosis.
Q42863338Sialylation of group B streptococcal capsular polysaccharide is mediated by cpsK and is required for optimal capsule polymerization and expression
Q34005157Sialylation of lipooligosaccharide cores affects immunogenicity and serum resistance of Campylobacter jejuni
Q99575141Structural and Biosynthetic Diversity of Nonulosonic Acids (NulOs) That Decorate Surface Structures in Bacteria
Q33769638The (alpha2-->8)-linked polysialic acid capsule and lipooligosaccharide structure both contribute to the ability of serogroup B Neisseria meningitidis to resist the bactericidal activity of normal human serum
Q33798900The capsular polysaccharide of Burkholderia pseudomallei contributes to survival in serum by reducing complement factor C3b deposition
Q33852676The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis.
Q34208951The interplay between Siglecs and sialylated pathogens
Q36340099Transcriptomic buffering of cryptic genetic variation contributes to meningococcal virulence
Q92765243Uptake of Sialic Acid by Nontypeable Haemophilus influenzae Increases Complement Resistance through Decreasing IgM-Dependent Complement Activation
Q35072338α-2,3-sialyltransferase expression level impacts the kinetics of lipooligosaccharide sialylation, complement resistance, and the ability of Neisseria gonorrhoeae to colonize the murine genital tract

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