Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development

scientific article published on July 2009

Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1473-3099(09)70132-X
P698PubMed publication ID19555901

P2093author name stringChristoph M Tang
Rachel M Exley
Helena Lo
P2860cites workLongitudinal study of asymptomatic meningococcal carriage in two Belgian populations of schoolchildrenQ71798023
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Mannose-binding lectin enhances phagocytosis and killing of Neisseria meningitidis by human macrophagesQ81072320
Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal diseaseQ83222896
Functional significance of factor H binding to Neisseria meningitidisQ83918204
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Complement factor H polymorphism in age-related macular degenerationQ24553334
Exploring the full spectrum of macrophage activationQ24653754
How neutrophils kill microbesQ24672245
The Neisseria meningitidis capsule is important for intracellular survival in human cellsQ24684877
AP endonuclease paralogues with distinct activities in DNA repair and bacterial pathogenesisQ27643887
Neisseria meningitidis recruits factor H using protein mimicry of host carbohydratesQ27653843
Complement. First of two partsQ28210663
Complement factor H variant increases the risk of age-related macular degenerationQ28239239
Neisseria meningitidis: an overview of the carriage stateQ28277386
Antimicrobial reactive oxygen and nitrogen species: concepts and controversiesQ28283086
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) IN MENINGOCOCCAL SEPTIC SHOCK AND EXPERIMENTAL HUMAN ENDOTOXEMIAQ64132774
Down-regulation of pili and capsule of Neisseria meningitidis upon contact with epithelial cells is mediated by CrgA regulatory proteinQ64449501
Effect of outer membrane vesicle vaccine against group B meningococcal disease in NorwayQ68322753
Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal diseaseQ71538870
Occurrence of alpha 2-8 linked polysialosyl units in a neural cell adhesion moleculeQ71725772
The NADPH oxidase and chronic granulomatous diseaseQ28289081
Complement factor H polymorphism and age-related macular degenerationQ29614931
Cationic antimicrobial peptide resistance in Neisseria meningitidisQ30857151
Large-scale analysis of the meningococcus genome by gene disruption: resistance to complement-mediated lysisQ30891451
Neutrophil granules: a library of innate immunity proteinsQ33290704
Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.Q33378236
Factor H family proteins and human diseasesQ33380214
The (alpha2-->8)-linked polysialic acid capsule and lipooligosaccharide structure both contribute to the ability of serogroup B Neisseria meningitidis to resist the bactericidal activity of normal human serumQ33769638
Update on meningococcal disease with emphasis on pathogenesis and clinical managementQ33812435
The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis.Q33852676
The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidisQ33879680
Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.Q33892877
Cytokine-mediated regulation of antimicrobial proteinsQ33983999
Epidemic meningitis, meningococcaemia, and Neisseria meningitidisQ34644525
Global adjustment of microbial physiology during free radical stressQ34695153
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Iron transport systems in Neisseria meningitidisQ35684980
Complement inhibitor C4b-binding protein-friend or foe in the innate immune system?Q35741515
PorA variable regions of Neisseria meningitidisQ35880198
Complement: central to innate immunity and bridging to adaptive responses.Q36064092
Meningococcal surrogates of protection--serum bactericidal antibody activityQ36065385
A universal vaccine for serogroup B meningococcusQ36101910
Endogenous sialylation of the lipooligosaccharides of Neisseria meningitidisQ36145701
Membrane complement regulatory proteinsQ36336220
Meningococcal genome dynamics.Q36343551
Available carbon source influences the resistance of Neisseria meningitidis against complementQ36402993
Complement and properidin deficiencies in meningococcal diseaseQ36411073
The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistanceQ36470692
Meningococcal carriage, alcohol consumption, and campus bar patronage in a serogroup C meningococcal disease outbreakQ36526303
Nitric oxide and reactive nitrogen species in airway epithelial signaling and inflammationQ36545300
A generic mechanism in Neisseria meningitidis for enhanced resistance against bactericidal antibodiesQ36699790
Cathelicidins and functional analogues as antisepsis molecules.Q36897327
The bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease.Q36902238
Analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin LL-37 in the innate immune response against periodontogenic bacteriaQ36932099
Alternative mechanisms of action of cationic antimicrobial peptides on bacteriaQ37014658
The role of epithelial beta-defensins and cathelicidins in host defense of the lungQ37030668
2. Dendritic cells as regulators of immunity and toleranceQ37074348
Vaccine potential of the Neisseria meningitidis 2086 lipoproteinQ37115883
Antimicrobial peptides in innate immune responses.Q37177017
The role of neutrophils and monocytes in innate immunityQ37177031
Immune deficiency disorders involving neutrophilsQ37255649
Lactoferrin: structure, function and applicationsQ37289535
Identification of 2 hypothetical genes involved in Neisseria meningitidis cathelicidin resistance.Q38291200
Mannose-binding lectin accelerates complement activation and increases serum killing of Neisseria meningitidis serogroup C.Q38297705
Binding of the complement inhibitor C4bp to serogroup B Neisseria meningitidisQ38326601
Functional characterization of an isogenic meningococcal alpha-2,3-sialyltransferase mutant: the role of lipooligosaccharide sialylation for serum resistance in serogroup B meningococciQ38341389
Complement factor C3 deposition and serum resistance in isogenic capsule and lipooligosaccharide sialic acid mutants of serogroup B Neisseria meningitidisQ38342684
Multiple mechanisms of phase variation of PorA in Neisseria meningitidisQ39517149
Interaction of Neisseria meningitidis with human dendritic cellsQ39529533
Lipooligosaccharide and polysaccharide capsule: virulence factors of Neisseria meningitidis that determine meningococcal interaction with human dendritic cellsQ39654947
Nitric oxide metabolism in Neisseria meningitidis.Q39679148
Bacterial [Cu,Zn]-cofactored superoxide dismutase protects opsonized, encapsulated Neisseria meningitidis from phagocytosis by human monocytes/macrophagesQ39730098
Recognition and control of neisserial infection by antibody and complement.Q40455856
The role of complement receptor 3 (CR3) in Neisseria gonorrhoeae infection of human cervical epitheliaQ40781106
Complement deficiency states and meningococcal diseaseQ40804745
Lipo-oligosaccharides (LOS) of mucosal pathogens: molecular mimicry and host-modification of LOS.Q40825138
Use of robotized DNA isolation and real-time PCR to quantify and identify close correlation between levels of Neisseria meningitidis DNA and lipopolysaccharides in plasma and cerebrospinal fluid from patients with systemic meningococcal diseaseQ41039806
Bacterial transferrin and lactoferrin receptorsQ41051437
The Effect of Chemoprophylactic Use of Rifampin and Minocycline on Rates of Carriage of Neisseria meningitidis in Army Recruits in FinlandQ41378539
Factor H-binding protein is important for meningococcal survival in human whole blood and serum and in the presence of the antimicrobial peptide LL-37.Q41825787
Genetic interactions of DNA repair pathways in the pathogen Neisseria meningitidisQ42412497
Nitric oxide detoxification systems enhance survival of Neisseria meningitidis in human macrophages and in nasopharyngeal mucosaQ42754647
Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanismQ43185362
Many carried meningococci lack the genes required for capsule synthesis and transportQ43450474
The differential response of human dendritic cells to live and killed Neisseria meningitidisQ44192675
Carbohydrate composition of meningococcal lipopolysaccharide modulates the interaction of Neisseria meningitidis with human dendritic cellsQ44634205
Optimization of virulence functions through glucosylation of Shigella LPS.Q45282739
Cationic polypeptides are required for antibacterial activity of human airway fluid.Q45946168
Cathelicidin antimicrobial peptides are expressed in salivary glands and salivaQ46204499
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformansQ46970232
Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: distinctive systems for different lifestylesQ47348879
The genetic basis of the phase variation repertoire of lipopolysaccharide immunotypes in Neisseria meningitidis.Q47904521
Contribution of genes from the capsule gene complex (cps) to lipooligosaccharide biosynthesis and serum resistance in Neisseria meningitidis.Q48084641
An anti-infective peptide that selectively modulates the innate immune responseQ50072960
Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines.Q51824053
Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients.Q51934437
Alternative activation deprives macrophages of a coordinated defense program to Mycobacterium tuberculosis.Q52934669
Naturally occurring insertional inactivation of theporAgene ofNeisseria meningitidisby integration of IS1301Q63371254
Association between combined properdin and mannose-binding lectin deficiency and infection with Neisseria meningitidisQ63728070
P433issue7
P921main subjectvaccineQ134808
Neisseria meningitidisQ154625
P304page(s)418-427
P577publication date2009-07-01
P1433published inLancet Infectious DiseasesQ15724248
P1476titleMechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development
P478volume9

Reverse relations

cites work (P2860)
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