Frontonasal process-specific disruption of AP-2alpha results in postnatal midfacial hypoplasia, vascular anomalies, and nasal cavity defects

scientific article published on March 2004

Frontonasal process-specific disruption of AP-2alpha results in postnatal midfacial hypoplasia, vascular anomalies, and nasal cavity defects is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YDBIO.2003.10.033
P698PubMed publication ID14975718
P5875ResearchGate publication ID8111458

P2093author name stringWilliams T
Nelson DK
P2860cites workMutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndromeQ24310222
Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndromeQ24311679
Mutations of the TWIST gene in the Saethre-Chotzen syndromeQ24311736
A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndromeQ24314986
Craniosynostosis in transgenic mice overexpressing Nell-1Q24553230
Generalized lacZ expression with the ROSA26 Cre reporter strainQ27860837
A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosisQ28249477
Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteinsQ28266897
Analysis of the DNA-binding and activation properties of the human transcription factor AP-2Q28271397
Transcription factor AP-2 essential for cranial closure and craniofacial developmentQ28513302
Tgf-beta1, Tgf-beta2, Tgf-beta3 and Msx2 expression is elevated during frontonasal suture morphogenesis and during active postnatal facial growthQ28567708
Requirement for AP-2alpha in cardiac outflow tract morphogenesisQ28584763
AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric miceQ28586197
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2Q28594321
Sonic hedgehog mediates the polarizing activity of the ZPAQ29616565
Expression of the T-box gene Eomesodermin during early mouse development.Q30630109
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesisQ33515610
From head to toe: conservation of molecular signals regulating limb and craniofacial morphogenesisQ33592088
Cranial sutures as intramembranous bone growth sitesQ34085716
Mechanisms balancing skeletal matrix synthesis and degradationQ34129759
Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigenQ34163571
Angiogenesis and bone growthQ34204716
Genetics of craniofacial development and malformationQ34271559
Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndromeQ34308670
Mechanisms of normal and tumor-derived angiogenesisQ34592513
FGF signaling pathways in endochondral and intramembranous bone development and human genetic diseaseQ34702208
Mechanobiology of craniofacial suturesQ35009879
Decreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disordersQ35787010
Contrasting roles for c-Myc and L-Myc in the regulation of cellular growth and differentiation in vivo.Q37694376
Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defectsQ38344566
Neurobehavioral evidence for the involvement of the vomeronasal system in mammalian reproductionQ39855349
Characterization of the endothelium-specific murine vascular endothelial growth factor receptor-2 (Flk-1) promoterQ41181627
Transforming growth factor-alpha-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation.Q41916797
Altered fracture repair in the absence of MMP9Q42641175
Tissue origins and interactions in the mammalian skull vaultQ43849664
Immunochemical and mechanical characterization of cartilage subtypes in rabbit.Q44074259
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.Q46288581
Identification and regulation of tissue‐specific cis‐acting elements associated with the human AP‐2α geneQ52099713
Postnatal Msx1 expression pattern in craniofacial, axial, and appendicular skeleton of transgenic mice from the first week until the second year.Q52135229
Epithelia are interchangeable between facial primordia of chick embryos and morphogenesis is controlled by the mesenchyme.Q52244290
Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system.Q52250604
Restricted growth at the frontonasal suture: alterations in craniofacial growth in rabbitsQ69772907
The relationship between masticatory function and craniofacial morphology. I. A cephalometric longitudinal analysis in the growing rat fed a soft dietQ69850668
Modulation of bovine articular chondrocyte gene expression in vitro by oxygen tensionQ73998897
Effects of insulin-like growth factor-I on nasopremaxillary growth under different masticatory loadings in growing miceQ74269142
Strain induced osteogenesis of the craniofacial suture upon controlled delivery of low-frequency cyclic forcesQ78586446
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)72-92
P577publication date2004-03-01
P1433published inDevelopmental BiologyQ3025402
P1476titleFrontonasal process-specific disruption of AP-2alpha results in postnatal midfacial hypoplasia, vascular anomalies, and nasal cavity defects
P478volume267

Reverse relations

cites work (P2860)
Q46256632A Cre transgene active in developing endodermal organs, heart, limb, and extra-ocular muscle
Q28587729AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis
Q37566996Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification
Q28588584An ENU-induced mutation in the Ankrd11 gene results in an osteopenia-like phenotype in the mouse mutant Yoda
Q37045093Analysis of TFAP2A mutations in Branchio-Oculo-Facial Syndrome indicates functional complexity within the AP-2α DNA-binding domain
Q40006898BCL11B regulates sutural patency in the mouse craniofacial skeleton
Q36404257Comparative ontogeny and phylogeny of the upper jaw skeleton in amniotes
Q24811874Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference
Q35740259Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway
Q35567806FGF8 is essential for formation of the ductal system in the male reproductive tract
Q38641260From Bench to Bedside and Back: Improving Diagnosis and Treatment of Craniofacial Malformations Utilizing Animal Models
Q37334244Frontal nasal prominence expression driven by Tcfap2a relies on a conserved binding site for STAT proteins
Q57444461Genetic Dissection of a Supergene Implicates in Craniofacial Evolution of Threespine Sticklebacks
Q50193517Hydronephrosis in the Wnt5a-ablated kidney is caused by an abnormal ureter-bladder connection
Q28592776Identification and analysis of a conserved Tcfap2a intronic enhancer element required for expression in facial and limb bud mesenchyme
Q39186926Long-range enhancers regulating Myc expression are required for normal facial morphogenesis
Q28589447Loss of AP-2alpha impacts multiple aspects of ventral body wall development and closure
Q36586217Molecular mechanisms of midfacial developmental defects
Q21563367Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects
Q28083779Receptor tyrosine kinase signaling: regulating neural crest development one phosphate at a time
Q54780420Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.
Q46596456Stage-dependent craniofacial defects resulting from Sprouty2 overexpression
Q24655671TFAP2A mutations result in branchio-oculo-facial syndrome
Q34818278Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage.
Q21184171The AP-2 family of transcription factors
Q39949448Variation in the Developmental and Morphological Interaction Between the Nasal Septum and Facial Skeleton
Q38344566Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects

Search more.