| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M306380200 |
| P698 | PubMed publication ID | 14570906 |
| P2093 | author name string | Timothy M Alce | |
| Waldemar Popik | |||
| P2860 | cites work | CXCR4 function requires membrane cholesterol: implications for HIV infection | Q43950699 |
| Cholesterol is essential for macrophage inflammatory protein 1 beta binding and conformational integrity of CC chemokine receptor 5. | Q44010372 | ||
| Clustering of a lipid-raft associated pool of ERM proteins at the immunological synapse upon T cell receptor or CD28 ligation | Q44030188 | ||
| Sphingolipid and cholesterol dependence of alphavirus membrane fusion. Lack of correlation with lipid raft formation in target liposomes | Q44077405 | ||
| Evidence for segregation of heterologous GPI-anchored proteins into separate lipid rafts within the plasma membrane | Q44119356 | ||
| Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling | Q44272110 | ||
| Identification of the residues in human CD4 critical for the binding of HIV. | Q44949776 | ||
| Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms. | Q54096893 | ||
| Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function | Q57275513 | ||
| Lipid-dependent Targeting of G Proteins into Rafts | Q57371836 | ||
| Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail | Q24310700 | ||
| p56Lck anchors CD4 to distinct microdomains on microvilli | Q24535092 | ||
| Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages | Q24541375 | ||
| Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2 | Q24676628 | ||
| Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody | Q27759364 | ||
| The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus | Q28259668 | ||
| LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation | Q28281516 | ||
| Human immunodeficiency virus induces phosphorylation of its cell surface receptor | Q28294051 | ||
| The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain | Q29618472 | ||
| Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction | Q30681334 | ||
| Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cells | Q30865013 | ||
| Human immunodeficiency virus infection is efficiently mediated by a glycolipid-anchored form of CD4. | Q33656997 | ||
| Glycosphingolipids promote entry of a broad range of human immunodeficiency virus type 1 isolates into cell lines expressing CD4, CXCR4, and/or CCR5. | Q33807605 | ||
| Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization | Q33933192 | ||
| Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus | Q34330529 | ||
| Binding of HIV-1 to its receptor induces tyrosine phosphorylation of several CD4-associated proteins, including the phosphatidylinositol 3-kinase | Q34423659 | ||
| The coxsackie B virus and adenovirus receptor resides in a distinct membrane microdomain | Q34471404 | ||
| Localization of CD4 and CCR5 in living cells | Q34859370 | ||
| Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems | Q34970141 | ||
| Direct visualization of Ras proteins in spatially distinct cell surface microdomains | Q36322914 | ||
| Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains | Q36370878 | ||
| Binding of human immunodeficiency virus type 1 to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway | Q36563863 | ||
| Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation | Q36845470 | ||
| Intestinal dipeptidyl peptidase IV is efficiently sorted to the apical membrane through the concerted action of N- and O-glycans as well as association with lipid microdomains | Q38293373 | ||
| Inhibition of CD3/CD28-mediated activation of the MEK/ERK signaling pathway represses replication of X4 but not R5 human immunodeficiency virus type 1 in peripheral blood CD4(+) T lymphocytes | Q39589753 | ||
| CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. | Q39605077 | ||
| CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells | Q39605953 | ||
| Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells | Q39683422 | ||
| Structural organization of authentic, mature HIV-1 virions and cores | Q39744816 | ||
| Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts | Q39789403 | ||
| HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains | Q40690112 | ||
| Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells | Q40776242 | ||
| Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1. | Q40788372 | ||
| Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection | Q40818759 | ||
| Association between GM3 and CD4-Ick complex in human peripheral blood lymphocytes | Q40825279 | ||
| Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane. | Q40855892 | ||
| Differential clustering of CD4 and CD3zeta during T cell recognition | Q40859028 | ||
| N-Glycans mediate the apical sorting of a GPI-anchored, raft-associated protein in Madin-Darby canine kidney cells | Q40938804 | ||
| Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated. | Q40977491 | ||
| CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. | Q41151327 | ||
| Regulation of Lck activity by CD4 and CD28 in the immunological synapse | Q43877164 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | membrane raft | Q424178 |
| P304 | page(s) | 704-712 | |
| P577 | publication date | 2003-10-21 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | CD4 receptor localized to non-raft membrane microdomains supports HIV-1 entry. Identification of a novel raft localization marker in CD4. | |
| P478 | volume | 279 |
| Q35683535 | A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization |
| Q33587774 | A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4 |
| Q40542002 | APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein |
| Q28259067 | Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains |
| Q42135688 | Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu. |
| Q33908887 | An envelope-determined, pH-independent endocytic route of viral entry determines the susceptibility of human immunodeficiency virus type 1 (HIV-1) and HIV-2 to Lv2 restriction. |
| Q34536866 | Atomic force microscopy studies provide direct evidence for dimerization of the HIV restriction factor APOBEC3G |
| Q39015489 | CD4 and CCR5 constitutively interact at the plasma membrane of living cells: a confocal fluorescence resonance energy transfer-based approach |
| Q35750979 | CD4 and CD8 T cells require different membrane gangliosides for activation |
| Q33112679 | CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers |
| Q37593203 | Ceramide, a target for antiretroviral therapy |
| Q34077742 | Differential functions of phospholipid binding and palmitoylation of tumour suppressor EWI2/PGRL |
| Q45303209 | Dynamic reorganization of chemokine receptors, cholesterol, lipid rafts, and adhesion molecules to sites of CD4 engagement |
| Q33810598 | Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site. |
| Q24792862 | Early steps of retrovirus replicative cycle |
| Q28478341 | Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion |
| Q30397007 | From structure to redox: The diverse functional roles of disulfides and implications in disease |
| Q41367745 | G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning |
| Q57035772 | HHIV Associated Neurodegenerative Disorders: A New Perspective on the Role of Lipid Rafts in Gp120-Mediated Neurotoxicity |
| Q45357578 | HIV entry in macrophages is dependent on intact lipid rafts |
| Q36798434 | HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: implications for therapy and vaccine development |
| Q54634678 | HIV-1 infects macrophages by exploiting an endocytic route dependent on dynamin, Rac1 and Pak1. |
| Q35157442 | HIV-associated nephropathy: pathogenesis |
| Q38066785 | Heterogeneity of gangliosides among T cell subsets |
| Q40126806 | Human ClC-6 is a late endosomal glycoprotein that associates with detergent-resistant lipid domains |
| Q39779756 | Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains |
| Q36540164 | Hydrophobic inactivation of influenza viruses confers preservation of viral structure with enhanced immunogenicity |
| Q43125086 | Identification of a lysine-rich region of Fas as a raft nanodomain targeting signal necessary for Fas-mediated cell death. |
| Q37033417 | Identification of the LWYIK motif located in the human immunodeficiency virus type 1 transmembrane gp41 protein as a distinct determinant for viral infection |
| Q41788529 | Lipid rafts of primary endothelial cells are essential for Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8-induced phosphatidylinositol 3-kinase and RhoA-GTPases critical for microtubule dynamics and nuclear delivery of viral DNA but dis |
| Q36659985 | Lipid rafts, detergent-resistant membranes, and raft targeting signals |
| Q21245090 | Loss of Niemann Pick type C proteins 1 and 2 greatly enhances HIV infectivity and is associated with accumulation of HIV Gag and cholesterol in late endosomes/lysosomes |
| Q40308237 | Marked differences in the structures and protein associations of lymphocyte and monocyte CD4: resolution of a novel CD4 isoform. |
| Q53458726 | Membrane insertion of the three main membranotropic sequences from SARS-CoV S2 glycoprotein. |
| Q38001407 | Membrane microdomains in immunity: glycosphingolipid-enriched domain-mediated innate immune responses |
| Q38246407 | Membrane organization of virus and target cell plays a role in HIV entry. |
| Q33908866 | Nef induces multiple genes involved in cholesterol synthesis and uptake in human immunodeficiency virus type 1-infected T cells |
| Q42497415 | PGE2 /EP4 Signaling Controls the Transfer of the Mammary Stem Cell State by Lipid Rafts in Extracellular Vesicles |
| Q33628817 | PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection |
| Q45308847 | Palmitoylation and intracellular domain interactions both contribute to raft targeting of linker for activation of T cells |
| Q39983486 | Plasma membrane cholesterol is required for efficient pseudorabies virus entry |
| Q34182524 | Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells |
| Q36857096 | Properties, functions, and drug targeting of the multifunctional nucleocapsid protein of the human immunodeficiency virus. |
| Q37359997 | Protein acylation and localization in T cell signaling (Review). |
| Q47132132 | Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging. |
| Q39118166 | Raft localization of CXCR4 is primarily required for X4-tropic human immunodeficiency virus type 1 infection |
| Q39069264 | Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1. |
| Q50737955 | Recycling of MUC1 is dependent on its palmitoylation. |
| Q36303032 | Restricted lateral mobility of plasma membrane CD4 impairs HIV-1 envelope glycoprotein mediated fusion |
| Q45424163 | Role of lipid rafts in virus replication |
| Q40310460 | Role of protein disulfide isomerase and other thiol-reactive proteins in HIV-1 envelope protein-mediated fusion. |
| Q35857576 | Sphingomyelinase restricts the lateral diffusion of CD4 and inhibits human immunodeficiency virus fusion |
| Q30501199 | Targeting and imaging single biomolecules in living cells by complementation-activated light microscopy with split-fluorescent proteins |
| Q37827428 | Tetherin and its viral antagonists |
| Q30497822 | Tetherin restricts direct cell-to-cell infection of HIV-1. |
| Q36444082 | The Localization of Cytochrome P450s CYP1A1 and CYP1A2 into Different Lipid Microdomains Is Governed by Their N-terminal and Internal Protein Regions. |
| Q34080779 | The Role of Lipids in Retrovirus Replication |
| Q40558019 | The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts |
| Q39030295 | The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. |
| Q35585420 | The role of cholesterol and sphingolipids in chemokine receptor function and HIV-1 envelope glycoprotein-mediated fusion |
| Q34290889 | The transmembrane region is responsible for targeting of adaptor protein LAX into "heavy rafts" |
| Q36156531 | The trinity of the cortical actin in the initiation of HIV-1 infection |
| Q35741691 | The tyrosine kinase inhibitor genistein blocks HIV-1 infection in primary human macrophages |
| Q33718427 | Vaccinia virus penetration requires cholesterol and results in specific viral envelope proteins associated with lipid rafts |
| Q33924533 | Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection. |
| Q33990483 | Viral entry, lipid rafts and caveosomes |
| Q57372497 | θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation |
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