| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/0014-5793(96)01047-2 |
| P8608 | Fatcat ID | release_xd64texkxjbgngqblz3ctv5yxa |
| P698 | PubMed publication ID | 8898102 |
| P5875 | ResearchGate publication ID | 14309114 |
| P2093 | author name string | Matsumoto A | |
| Ohashi H | |||
| Kato T | |||
| Miyazaki H | |||
| Morita H | |||
| Tahara T | |||
| P2860 | cites work | Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways | Q72315745 |
| Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin | Q24316187 | ||
| Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily | Q24564819 | ||
| The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase | Q24567715 | ||
| Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells | Q24615593 | ||
| Functional regions of the mouse interleukin-10 receptor cytoplasmic domain | Q24651335 | ||
| Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors | Q28235378 | ||
| Cytokine signal transduction | Q28258951 | ||
| The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl | Q28287528 | ||
| Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways | Q28287538 | ||
| The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells | Q28609032 | ||
| Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells | Q29614545 | ||
| Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases | Q29618331 | ||
| Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes | Q30193572 | ||
| Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation | Q34207417 | ||
| Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission | Q34229092 | ||
| Ligand-induced activation of chimeric receptors between the erythropoietin receptor and receptor tyrosine kinases | Q34912136 | ||
| Growth of factor-dependent hemopoietic precursor cell lines | Q36344083 | ||
| Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis | Q36551756 | ||
| Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin | Q36559653 | ||
| Distinct Regions of the Human Granulocyte-Colony-Stimulating Factor Receptor Cytoplasmic Domain Are Required for Proliferation and Gene Induction | Q36678736 | ||
| Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation | Q36756480 | ||
| Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3. | Q38292693 | ||
| Cytokine receptor signalling | Q40416594 | ||
| Dimerization of cell surface receptors in signal transduction | Q40579106 | ||
| Thrombopoietin induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in a human thrombopoietin-dependent cell line | Q41260590 | ||
| TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules | Q41272946 | ||
| Thrombopoietin Induces Megakaryocyte Differentiation in Hematopoietic Progenitor FDC-P2 Cells | Q41308518 | ||
| Purification and characterization of thrombopoietin | Q41328061 | ||
| Distinct cytoplasmic regions of the growth hormone receptor are required for activation of JAK2, mitogen-activated protein kinase, and transcription | Q41438563 | ||
| Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. | Q41457316 | ||
| Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo | Q41460916 | ||
| Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. | Q41460921 | ||
| The c-kit receptor transduces the stem cell factor-triggered growth signal in murine interleukin-3-dependent cell line. | Q41506573 | ||
| Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor | Q41526771 | ||
| SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases | Q41566173 | ||
| Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines | Q41579098 | ||
| Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation | Q70685515 | ||
| Thrombopoietin induces activation of at least two distinct signaling pathways | Q70869083 | ||
| P433 | issue | 2-3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 228-234 | |
| P577 | publication date | 1996-10-01 | |
| P1433 | published in | FEBS Letters | Q1388051 |
| P1476 | title | Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation | |
| P478 | volume | 395 |
| Q42802190 | A new feature of Mpl receptor: ligand-induced transforming activity in FRE rat fibroblasts |
| Q33344045 | Autoantibody to c-Mpl (thrombopoietin receptor) in systemic lupus erythematosus: relationship to thrombocytopenia with megakaryocytic hypoplasia |
| Q60043951 | C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation |
| Q40844906 | Cbl: complex formation and functional implications |
| Q36571164 | Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway |
| Q39445261 | Design of conditionally active STATs: insights into STAT activation and gene regulatory function |
| Q40729360 | Dissection of the cytoplasmic domains of cytokine receptors involved in STAT and Ras dependent proliferation |
| Q35005652 | Enu mutagenesis identifies a novel platelet phenotype in a loss-of-function Jak2 allele |
| Q73680625 | Functional analysis of the C-terminal region of recombinant human thrombopoietin. C-terminal region of thrombopoietin is a "shuttle" peptide to help secretion |
| Q33775054 | Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line |
| Q40420997 | Janus kinases affect thrombopoietin receptor cell surface localization and stability |
| Q28115996 | Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions |
| Q43166825 | Peptide immobilized on gold particles enhances cell growth |
| Q33504684 | Plasma thrombopoietin (TPO) levels and expression of TPO receptor on platelets in patients with myelodysplastic syndromes |
| Q48012306 | Quantitative analysis of thrombopoietin receptors on human megakaryocytes. |
| Q24554307 | Regulatory and signaling properties of the Vav family |
| Q39450334 | Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo |
| Q40735322 | Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation |
| Q33440994 | The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin |
| Q34658539 | The molecular and cellular biology of thrombopoietin: the primary regulator of platelet production |
| Q36144586 | Thrombin cleaves recombinant human thrombopoietin: one of the proteolytic events that generates truncated forms of thrombopoietin |
| Q33330090 | Thrombopoietin |
| Q33392695 | Thrombopoietin Factors |
| Q28145736 | Thrombopoietin induces an SH2-containing protein, CIS1, which binds to Mpl: involvement of the ubiquitin proteosome pathway |
| Q38314398 | Thrombopoietin induces the generation of distinct Stat1, Stat3, Stat5a and Stat5b homo- and heterodimeric complexes with different kinetics in human platelets |
| Q47735575 | Thrombopoietin level is inversely related to blast count, not platelet number, in Down syndrome neonates with transient myeloproliferative disorder |
| Q28142867 | Thrombopoietin signal transduction requires functional JAK2, not TYK2 |
| Q41047876 | Thrombopoietin stimulates proliferation and megakaryocytic differentiation of mouse pro-B cell line BF-TE22 |
| Q40970057 | Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e |
| Q33967880 | Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways |
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