| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0898-6568(97)00179-4 |
| P698 | PubMed publication ID | 9720760 |
| P2093 | author name string | Y C Liu | |
| A Altman | |||
| P2860 | cites work | C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins | Q24305258 |
| Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G | Q24309656 | ||
| The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner | Q24310761 | ||
| Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif | Q24311683 | ||
| Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation | Q24313100 | ||
| Activation-modulated association of 14-3-3 proteins with Cbl in T cells | Q24321362 | ||
| Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine | Q24322674 | ||
| 14-3-3 proteins associate with cdc25 phosphatases | Q24324041 | ||
| Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation | Q24336399 | ||
| Identification and preliminary characterization of a protein motif related to the zinc finger | Q24563322 | ||
| Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells | Q24563675 | ||
| v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas | Q24624849 | ||
| Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity | Q24645473 | ||
| Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function | Q24648178 | ||
| Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G | Q24651040 | ||
| Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways | Q27729753 | ||
| Crystal structure of the zeta isoform of the 14-3-3 protein | Q27729754 | ||
| Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling | Q28268458 | ||
| Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors | Q28277651 | ||
| A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells | Q28289338 | ||
| Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl | Q28294930 | ||
| B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins | Q28298373 | ||
| Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL) | Q28307140 | ||
| Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases | Q28507413 | ||
| Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells | Q28575312 | ||
| Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes | Q28585310 | ||
| The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells | Q28609032 | ||
| Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase | Q28609041 | ||
| p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase | Q28610005 | ||
| Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice | Q29547898 | ||
| Signal transduction by lymphocyte antigen receptors | Q29619894 | ||
| D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites. | Q30176514 | ||
| EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene | Q30176545 | ||
| Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development. | Q30176591 | ||
| Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins | Q30176934 | ||
| Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation | Q30177028 | ||
| p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells | Q30192709 | ||
| Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells | Q30192771 | ||
| c-Cbl is inducibly tyrosine-phosphorylated by epidermal growth factor stimulation in fibroblasts, and constitutively tyrosine-phosphorylated and associated with v-Src in v-src-transformed fibroblasts | Q30192884 | ||
| Coupling of the Proto-oncogene Product c-Cbl to the Epidermal Growth Factor Receptor | Q30192999 | ||
| Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia | Q30193124 | ||
| Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl | Q30193172 | ||
| The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase | Q30193184 | ||
| The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase | Q30193228 | ||
| Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells | Q30193317 | ||
| Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors | Q30193495 | ||
| Crk interacts with tyrosine-phosphorylated p116 upon T cell activation | Q30193645 | ||
| The GRB2/Sem-5 adaptor protein | Q30194559 | ||
| ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling | Q33886341 | ||
| Interaction of the c-cbl proto-oncogene product with the Tyk-2 protein tyrosine kinase | Q34063147 | ||
| Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling | Q36366183 | ||
| The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein | Q36832426 | ||
| Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter | Q38289112 | ||
| Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation | Q38352135 | ||
| c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption. | Q38352423 | ||
| Dimerization of cell surface receptors in signal transduction | Q40579106 | ||
| NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes | Q40693171 | ||
| Bcr and Raf form a complex in vivo via 14-3-3 proteins | Q40789573 | ||
| LET-23-mediated signal transduction during Caenorhabditis elegans development | Q40974398 | ||
| Multiple p21ras effector pathways regulate nuclear factor of activated T cells. | Q41076338 | ||
| The cbl oncogene: a novel substrate of protein tyrosine kinases | Q41082091 | ||
| Complex complexes: signaling at the TCR. | Q41113361 | ||
| Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL. | Q41119063 | ||
| Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages | Q41150880 | ||
| Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism | Q41168715 | ||
| Induction of CD38/NADase and its monoclonal antibody-induced tyrosine phosphorylation in human leukemia cell lines | Q41198363 | ||
| Specific association of phosphatidylinositol 3-kinase with the protooncogene product Cbl in Fc gamma receptor signaling | Q41216978 | ||
| TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules | Q41272946 | ||
| Views on Vav. | Q41472325 | ||
| Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation | Q41514671 | ||
| p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells | Q41517120 | ||
| p21ras mediates control of IL-2 gene promoter function in T cell activation. | Q41545934 | ||
| Relationship of the human protooncogene CBL2 on 11q23 to the t(4;11), t(11;22), and t(11;14) breakpoints | Q41701344 | ||
| Regulation of the association of p120cbl with Grb2 in Jurkat T cells | Q42523856 | ||
| Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells. | Q42528757 | ||
| Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling | Q42802564 | ||
| The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway. | Q45989111 | ||
| Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. | Q52516078 | ||
| Does this have a familiar RING? | Q55920907 | ||
| The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway | Q56602500 | ||
| Thrombopoietin induces activation of at least two distinct signaling pathways | Q70869083 | ||
| Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells | Q71742747 | ||
| Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice | Q71800467 | ||
| Association of phosphatidylinositol 3-kinase with the proto-oncogene product Cbl upon CD38 ligation by a specific monoclonal antibody in THP-1 cells | Q71830078 | ||
| 14-3-3 proteins on the MAP | Q72139467 | ||
| Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways | Q72315745 | ||
| Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation | Q73174651 | ||
| The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase | Q73224118 | ||
| P433 | issue | 6 | |
| P1104 | number of pages | 9 | |
| P304 | page(s) | 377-385 | |
| P577 | publication date | 1998-06-01 | |
| P1433 | published in | Cellular Signalling | Q1524097 |
| P1476 | title | Cbl: complex formation and functional implications | |
| P478 | volume | 10 |
| Q30164758 | 70Z/3 Cbl induces PLCγ1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism |
| Q35179402 | A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis |
| Q24537413 | APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes |
| Q34044528 | Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase |
| Q38316067 | Association of Cbl with Fms and p85 in response to macrophage colony-stimulating factor. |
| Q24304461 | CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases |
| Q30840928 | Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding |
| Q38112644 | Cbl-family proteins as regulators of cytoskeleton-dependent phenomena |
| Q42815138 | Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain |
| Q22253208 | Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl |
| Q28679173 | Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers |
| Q33911148 | Directing traffic in neural cells: determinants of receptor tyrosine kinase localization and cellular responses |
| Q42467870 | Dual regulation of T cell receptor-mediated signaling by oncogenic Cbl mutant 70Z. |
| Q28586578 | Essential role for Gab2 in the allergic response |
| Q28142352 | Evidence for direct interaction between Sprouty and Cbl |
| Q44389555 | Expression and function of Cbl-b in T cells from patients with systemic lupus erythematosus, and detection of the 2126 A/G Cblb gene polymorphism in the Mexican mestizo population. |
| Q36375943 | Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. |
| Q33309487 | Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells |
| Q77649221 | Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 |
| Q33940377 | Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells |
| Q43982351 | Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor |
| Q28574498 | Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk |
| Q40729416 | Isolation and characterization of a novel, transforming allele of the c-Cbl proto-oncogene from a murine macrophage cell line |
| Q28207560 | Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation |
| Q30175408 | Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins |
| Q35014319 | Molecular recognition by SH2 domains |
| Q34242706 | Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways |
| Q35901705 | Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia |
| Q42909224 | Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk. |
| Q42829140 | Potentiation of insulin-related signal transduction by a novel protein-tyrosine phosphatase inhibitor, Et-3,4-dephostatin, on cultured 3T3-L1 adipocytes |
| Q95780651 | Primate evolution--in and out of Africa |
| Q33588931 | Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance |
| Q32138771 | RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation |
| Q47577112 | Reciprocal regulation of MelCAM and AKT in human melanoma |
| Q28140642 | Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells |
| Q33784061 | Regulation of integrin function by T cell activation: points of convergence and divergence |
| Q34317446 | Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations |
| Q38363901 | Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation |
| Q22009910 | SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity |
| Q34331449 | Signal transduction via the growth hormone receptor |
| Q27617539 | Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase |
| Q30168090 | T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein |
| Q45263240 | TGF-beta, c-Cbl, and PDGFR-alpha the in mammary stroma |
| Q33702164 | The Cbl protooncoprotein: a negative regulator of immune receptor signal transduction |
| Q30167736 | The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl |
| Q58179986 | The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase |
| Q33292565 | The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function |
| Q33653644 | The function of small GTPases in signaling by immune recognition and other leukocyte receptors |
| Q22009088 | The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase |
| Q42169339 | The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport |
| Q43877176 | Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor |
| Q22008757 | Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation |
| Q28206048 | Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte |
| Q28213787 | c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPases |
| Q37377645 | c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest |
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