Inflammation-induced foam cell formation in chronic inflammatory disease.

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Inflammation-induced foam cell formation in chronic inflammatory disease. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/ICB.2015.26
P698PubMed publication ID25753272

P50authorAnthony JaworowskiQ99597122
Thomas A AngelovichQ56986249
P2093author name stringAnna C Hearps
P2860cites workAgeing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosisQ59326346
Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via Reduced Macrophage Activation, Foam Cell Formation, and MigrationQ63915472
Peripheral blood mononuclear phagocyte subpopulations as cellular markers in hypercholesterolemiaQ71930679
Association of endotoxemia with carotid atherosclerosis and cardiovascular disease: prospective results from the Bruneck StudyQ73250259
Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activationQ77753940
Characterization of the expression of TLR2 (toll-like receptor 2) and TLR4 on circulating monocytes in coronary artery diseaseQ81429037
Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaqueQ81444765
Cardiovascular death in rheumatoid arthritis: a population-based studyQ81484761
The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell populationQ82065955
Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Krüppel-like factor 2Q82937913
HIV infection induces age-related changes to monocytes and innate immune activation in young men that persist despite combination antiretroviral therapyQ83399154
HMG-CoA reductase inhibitor simvastatin suppresses Toll-like receptor 2 ligand-induced activation of nuclear factor kappa B by preventing RhoA activation in monocytes from rheumatoid arthritis patientsQ84232214
CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney diseaseQ85189304
Prediction of Coronary Heart Disease Using Risk Factor CategoriesQ22241923
Microbial translocation is a cause of systemic immune activation in chronic HIV infectionQ22251054
Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophagesQ24310677
The response-to-retention hypothesis of early atherogenesisQ24629974
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responsesQ24631052
HIV infection and the risk of acute myocardial infarctionQ27347231
Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathwayQ28198343
Reciprocal regulation of inflammation and lipid metabolism by liver X receptorsQ28202771
Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formationQ28260494
Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesisQ28509382
The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAsQ28538471
HIV-derived ssRNA binds to TLR8 to induce inflammation-driven macrophage foam cell formationQ28541572
Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart diseaseQ33234397
Human immunodeficiency virus impairs reverse cholesterol transport from macrophagesQ33262244
Association of HIV infection, demographic and cardiovascular risk factors with all-cause mortality in the recent HAART era.Q33563357
Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activationQ33597485
Bacteria and bacterial DNA in atherosclerotic plaque and aneurysmal wall biopsies from patients with and without periodontitisQ33624352
Dendritic cells in atherosclerotic diseaseQ33651897
MicroRNA-155 deficiency results in decreased macrophage inflammation and attenuated atherogenesis in apolipoprotein E-deficient mice.Q33675241
Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic miceQ33905765
Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosusQ33974679
Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemiaQ33997331
ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced toleranceQ34053118
Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cellsQ34123258
MicroRNA-155 silencing enhances inflammatory response and lipid uptake in oxidized low-density lipoprotein-stimulated human THP-1 macrophagesQ34146738
Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritisQ34182804
Inflammatory markers and onset of cardiovascular events: results from the Health ABC studyQ34271279
The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patientsQ34306860
Role of toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein E-deficient miceQ34555906
Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected womenQ34568436
Sex differences in monocyte activation in systemic lupus erythematosus (SLE).Q34653871
Hepatitis C virus infection and the risk of coronary diseaseQ34802706
Circulating markers of inflammation and atherosclerosisQ35201144
Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromataQ35251005
Endothelial cell activation promotes foam cell formation by monocytes following transendothelial migration in an in vitro model.Q36129306
Biomarkers of microbial translocation and macrophage activation: association with progression of subclinical atherosclerosis in HIV-1 infectionQ36330954
HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitroQ36352592
MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophagesQ36357815
Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndromeQ36440077
Endotoxemia is related to systemic inflammation and atherosclerosis in peritoneal dialysis patientsQ36666840
Increased responsiveness to toll-like receptor 4 stimulation in peripheral blood mononuclear cells from patients with recent onset rheumatoid arthritisQ36731722
Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein EQ36986664
Inflammation impairs reverse cholesterol transport in vivo.Q37077796
Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic miceQ37151524
TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosisQ37196471
Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptakeQ37340933
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men.Q37363683
Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus diseaseQ37390635
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaquesQ37416056
Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology studyQ37457772
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activationQ37856309
Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2.Q37860795
Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr-/- miceQ37864162
Infections, immunity, and atherosclerosis: associations of antibodies to Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus with immune reactions to heat-shock protein 60 and carotid or femoral atherosclerosisQ37875835
A Chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharideQ37879971
Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit modelQ37881464
Chlamydia pneumoniae, cytomegalovirus, and herpes simplex virus in atherosclerosis of the carotid arteryQ37882074
Monocyte and macrophage dynamics during atherogenesisQ37890185
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndromeQ38307931
MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways.Q39144268
Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formationQ39207512
TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice.Q39260793
CD14++CD16+ monocytes independently predict cardiovascular events: a cohort study of 951 patients referred for elective coronary angiographyQ39549158
Interferon-α priming promotes lipid uptake and macrophage-derived foam cell formation: a novel link between interferon-α and atherosclerosis in lupusQ39600465
Inflammatory stress increases unmodified LDL uptake via LDL receptor: an alternative pathway for macrophage foam-cell formationQ39837080
TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formationQ39887996
Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL.Q40255872
Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol MetabolismQ40622775
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cellsQ40691206
Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formationQ41579091
Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptorsQ42101285
Cytomegalovirus coinfection is associated with an increased risk of severe non-AIDS-defining events in a large cohort of HIV-infected patientsQ42202541
Associations between surface markers on blood monocytes and carotid atherosclerosis in HIV-positive individuals.Q42238390
Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophagesQ42396896
Expression of miR-146a/b is associated with the Toll-like receptor 4 signal in coronary artery disease: effect of renin-angiotensin system blockade and statins on miRNA-146a/b and Toll-like receptor 4 levelsQ43044147
Activation profile of Toll-like receptors of peripheral blood lymphocytes in patients with systemic lupus erythematosus.Q43258243
Cytomegalovirus infection increases development of atherosclerosis in Apolipoprotein-E knockout miceQ43614826
Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational studyQ43865213
Accumulation of foam cells in liver X receptor-deficient miceQ44114728
Impact of HIV infection and HAART on serum lipids in men.Q44473694
The expression of cholesterol metabolism genes in monocytes from HIV-infected subjects suggests intracellular cholesterol accumulation.Q44482690
Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathwaysQ44807760
Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages.Q45966541
Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndromeQ46481417
Antiinflammatory and antiatherogenic effects of the NF-kappaB inhibitor acetyl-11-keto-beta-boswellic acid in LPS-challenged ApoE-/- miceQ46886406
Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritisQ47596885
Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.Q47608596
Toll-like receptor 4 mediates oxidized LDL-induced macrophage differentiation to foam cells.Q50526173
Cohort study of cytomegalovirus infection as a risk factor for carotid intimal-medial thickening, a measure of subclinical atherosclerosis.Q51012002
Diverse bacteria promote macrophage foam cell formation via Toll-like receptor-dependent lipid body biosynthesis.Q54336706
Toll-like receptor-4 and mitogen-activated protein kinase signal system are involved in activation of dendritic cells in patients with acute coronary syndrome.Q54539959
Human Atherosclerotic Plaque Contains Viable Invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalisQ56626010
Pivotal role of M-DC8+ monocytes from viremic HIV-infected patients in TNF overproduction in response to microbial productsQ57095873
Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage ActivationQ57315829
Toll-like Receptor 4 Polymorphisms and AtherogenesisQ59273869
P433issue8
P921main subjectinflammationQ101991
P304page(s)683-693
P577publication date2015-03-10
P1433published inImmunology & Cell BiologyQ13731918
P1476titleInflammation-induced foam cell formation in chronic inflammatory disease
P478volume93

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cites work (P2860)
Q58559667Anti-inflammatory and Antioxidant Activities of the Extracts from Leaves and Stems of Polygonum odoratum Lour
Q92670725Arterial Hypertension and Interleukins: Potential Therapeutic Target or Future Diagnostic Marker?
Q91991590FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation
Q35902378Gene-Diet Interaction between SIRT6 and Soybean Intake for Different Levels of Pulse Wave Velocity
Q91693184Ginkgolide B Mediated Alleviation of Inflammatory Cascades and Altered Lipid Metabolism in HUVECs via Targeting PCSK-9 Expression and Functionality
Q91638984How Monocytes Contribute to Increased Risk of Atherosclerosis in Virologically-Suppressed HIV-Positive Individuals Receiving Combination Antiretroviral Therapy
Q55446683Inflammation, not Cholesterol, Is a Cause of Chronic Disease.
Q37690728LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies
Q37017196MicroRNA: A new therapeutic strategy for cardiovascular diseases
Q50082613Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.
Q37378957Monocytes from HIV-infected individuals show impaired cholesterol efflux and increased foam cell formation after transendothelial migration
Q57177277Preeclampsia and Related Cardiovascular Risk: Common Genetic Background
Q46472418Quantification of Monocyte Transmigration and Foam Cell Formation from Individuals with Chronic Inflammatory Conditions
Q37622040Quercetin Inhibits LPS-Induced Inflammation and ox-LDL-Induced Lipid Deposition
Q36719371Salusin-β induces foam cell formation and monocyte adhesion in human vascular smooth muscle cells via miR155/NOX2/NFκB pathway
Q57922196Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific
Q27313354The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance
Q48223389The phosphatase PPM1A controls monocyte-to-macrophage differentiation

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