Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma

scientific article published on 26 May 2016

Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.9640
P932PMC publication ID5386642
P698PubMed publication ID27244893

P50authorRalph WeichselbaumQ19668192
Everett E VokesQ73567428
Ravi SalgiaQ73567837
Tanguy Y SeiwertQ89776148
Mark W. LingenQ113027272
Rifat HasinaQ113027582
Rajani KantetiQ113027596
P2093author name stringCleo E Rolle
Mosmi Surati
Sapana Vora
Yi-Hung Carol Tan
George B Carey
P2860cites workStructural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-bQ27646953
Cancer statistics, 2014Q27861018
c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitinationQ28203098
The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-MetQ28207199
p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-CblQ28280007
The Cbl family of ubiquitin ligases: critical negative regulators of tyrosine kinase signaling in the immune systemQ28634501
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neckQ29619277
The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.Q30177048
The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinomaQ30494514
Platinum-based chemotherapy plus cetuximab in head and neck cancerQ33381094
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survivalQ33515519
CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinasesQ33528991
Epidermal growth factor receptor inhibitor gefitinib added to chemoradiotherapy in locally advanced head and neck cancerQ33990915
Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylationQ34097397
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neckQ34533587
Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patientsQ35600799
The Cbl family proteins: ring leaders in regulation of cell signalingQ36495318
Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathwayQ36565319
c-Met and hepatocyte growth factor: potential as novel targets in cancer therapyQ36731520
The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear proteinQ36832426
Expression and mutational analysis of MET in human solid cancersQ36975055
Head and neck cancer: changing epidemiology, diagnosis, and treatmentQ37125036
Cytogenetic evidence of the multistep origin of head and neck squamous cell carcinomasQ41117144
Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapyQ41725449
Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasmsQ42795736
Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the HeadQ56688854
Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-BaseQ57949385
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectmutational analysisQ1955810
P304page(s)18726-18734
P577publication date2016-05-26
P1433published inOncotargetQ1573155
P1476titleExpression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma
P478volume8

Reverse relations

Q89739717Two miRNA prognostic signatures of head and neck squamous cell carcinoma: A bioinformatic analysis based on the TCGA datasetcites workP2860

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