Stem cell transplantation before birth - a realistic option for treatment of osteogenesis imperfecta?

scientific article published on 11 May 2015

Stem cell transplantation before birth - a realistic option for treatment of osteogenesis imperfecta? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/PD.4611
P698PubMed publication ID25962526

P50authorCecilia GötherströmQ47159961
P2093author name stringMagnus Westgren
P2860cites workBisphosphonate therapy for osteogenesis imperfectaQ24194821
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Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration.Q51210701
Immunologic properties of human fetal mesenchymal stem cells.Q51718048
Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse.Q51998594
Human first-trimester fetal MSC express pluripotency markers and grow faster and have longer telomeres than adult MSC.Q52001009
Transplantation of human fetal blood stem cells in the osteogenesis imperfecta mouse leads to improvement in multiscale tissue properties.Q53101655
Analysis of tissues following mesenchymal stromal cell therapy in humans indicates limited long-term engraftment and no ectopic tissue formation.Q53171235
Angulated femurs and the skeletal dysplasias: experience of the International Skeletal Dysplasia Registry (1988-2006).Q53236734
Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.Q53328521
First-trimester diagnosis of osteogenesis imperfecta associated with encephalocele by conventional and three-dimensional ultrasound.Q54591302
Fetal therapy: 2020 and beyondQ58009820
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Fetal Mesenchymal Stem-Cell Engraftment in Bone after In Utero Transplantation in a Patient with Severe Osteogenesis ImperfectaQ58789209
Homozygosity for a missense mutation in SERPINH1, which encodes the collagen chaperone protein HSP47, results in severe recessive osteogenesis imperfectaQ24632692
Osteogenesis imperfecta due to mutations in non-collagenous genes: lessons in the biology of bone formationQ26824200
New genes in bone development: what's new in osteogenesis imperfectaQ26864752
Osteogenesis imperfecta: clinical diagnosis, nomenclature and severity assessmentQ27025005
Multilineage potential of adult human mesenchymal stem cellsQ27860737
Osteogenesis imperfecta: prospects for molecular therapeuticsQ28139390
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II studyQ29617267
Mutations in the gene encoding the RER protein FKBP65 cause autosomal-recessive osteogenesis imperfectaQ33772970
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfectaQ33855709
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of boneQ34066339
Cyclic administration of pamidronate in children with severe osteogenesis imperfectaQ34067536
Immunomodulatory effects of fetal and adult mesenchymal stem cellsQ35601901
Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfectaQ35796570
Procollagen trafficking, processing and fibrillogenesis.Q36078993
Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms.Q36206449
Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs).Q36372136
Fetal stem-cell transplantationQ37012798
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfectaQ37271063
Potential of human fetal chorionic stem cells for the treatment of osteogenesis imperfectaQ37523900
Prenatal sonographic diagnosis of skeletal dysplasiasQ37528232
Pre- and postnatal transplantation of fetal mesenchymal stem cells in osteogenesis imperfecta: a two-center experienceQ37585445
Classification of Osteogenesis Imperfecta revisitedQ37624972
Early prenatal diagnosis of skeletal anomaliesQ37826401
New perspectives on osteogenesis imperfectaQ37889113
Procedure-related complications and perinatal outcome after intrauterine transfusions in red cell alloimmunization in Stockholm.Q37949199
The potential of human fetal mesenchymal stem cells for off-the-shelf bone tissue engineering applicationQ37973181
Recessive osteogenesis imperfecta: clinical, radiological, and molecular findingsQ38025998
Prenatal diagnosis of osteogenesis imperfecta type II by three-dimensional computed tomography: the current state of fetal computed tomographyQ38062559
Intrauterine blood transfusion: current indications and associated risksQ38218054
What is new in genetics and osteogenesis imperfecta classification?Q38232156
Superior osteogenic capacity for bone tissue engineering of fetal compared with perinatal and adult mesenchymal stem cellsQ38512406
EMQN best practice guidelines for the laboratory diagnosis of osteogenesis imperfecta.Q39701074
Non-invasive prenatal diagnosis of osteogenesis imperfectaQ40888768
Mutation Analysis of COL1A1 and COL1A2 in Fetuses with Osteogenesis Imperfecta Type II/III.Q41509333
Comparative osteogenic transcription profiling of various fetal and adult mesenchymal stem cell sourcesQ42437471
Characterising and treating osteogenesis imperfectaQ42905532
Biochemical screening of type I collagen in osteogenesis imperfecta: detection of glycine substitutions in the amino end of the alpha chains requires supplementation by molecular analysisQ43169907
Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfectaQ45875073
Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta miceQ46925534
P433issue9
P921main subjectosteogenesis imperfectaQ749409
P304page(s)827-832
P577publication date2015-05-11
P1433published inPrenatal DiagnosisQ15760059
P1476titleStem cell transplantation before birth - a realistic option for treatment of osteogenesis imperfecta?
P478volume35

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cites work (P2860)
Q64039618Current and Emerging Therapeutic Options for the Management of Rare Skeletal Diseases
Q57839567Exome sequencing for prenatal diagnosis of fetuses with sonographic abnormalities
Q38998578Pharmacological and biological therapeutic strategies for osteogenesis imperfecta.
Q34558273Promises, pitfalls and practicalities of prenatal whole exome sequencing
Q88212766Rapid prenatal diagnosis using targeted exome sequencing: a cohort study to assess feasibility and potential impact on prenatal counseling and pregnancy management
Q91688583Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches
Q36183143Transcription factor ZNF25 is associated with osteoblast differentiation of human skeletal stem cells

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