| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Magali Cucchiarini | Q64731259 |
| P2093 | author name string | Henning Madry | |
| Patrick Orth | |||
| P2860 | cites work | Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis | Q24308841 |
| Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee | Q71129544 | ||
| Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis | Q71503443 | ||
| Gene targeting in stem cells from individuals with osteogenesis imperfecta | Q24310539 | ||
| Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice | Q24321587 | ||
| Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair | Q24558762 | ||
| Fibrochondrogenesis of hESCs: growth factor combinations and cocultures | Q24594539 | ||
| Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure | Q24634002 | ||
| Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function | Q24642759 | ||
| Born to run; the story of the PEPCK-Cmus mouse | Q24652743 | ||
| The menisci: basic science and advances in treatment | Q24672794 | ||
| Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4 | Q24792474 | ||
| A new technique for the assay of infectivity of human adenovirus 5 DNA | Q27860797 | ||
| Allograft meniscal transplantation: background, techniques, and results | Q28190412 | ||
| Stem cell therapy in a caprine model of osteoarthritis | Q28191365 | ||
| Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects | Q28203658 | ||
| Meniscal allografts: indications and outcomes | Q28240916 | ||
| Regeneration of meniscal cartilage with use of a collagen scaffold. Analysis of preliminary data | Q28257582 | ||
| Effect of lateral meniscal allograft sizing on contact mechanics of the lateral tibial plateau: an experimental study in human cadaveric knee joints | Q28259196 | ||
| The microvasculature of the meniscus and its response to injury. An experimental study in the dog | Q28272005 | ||
| Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein | Q28281538 | ||
| The healing and regeneration of articular cartilage | Q28292890 | ||
| PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth | Q28506149 | ||
| Maturational disturbance of chondrocytes in Cbfa1-deficient mice | Q28506259 | ||
| Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis | Q28564933 | ||
| Sox9 is required for cartilage formation | Q28588649 | ||
| Tissue engineering | Q29617288 | ||
| Chondrocyte transplantation into articular cartilage defects with use of calcium alginate: the fate of the cells. | Q30311192 | ||
| Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA. | Q30453928 | ||
| Adalimumab for long-term treatment of psoriatic arthritis: forty-eight week data from the adalimumab effectiveness in psoriatic arthritis trial | Q31096607 | ||
| BMP-2 induction and TGF-beta 1 modulation of rat periosteal cell chondrogenesis | Q32162727 | ||
| Characterisation of human knee meniscus cell phenotype | Q33217922 | ||
| Neural and vascular anatomy of the menisci of the human knee | Q33547404 | ||
| Disease-inducible transgene expression from a recombinant adeno-associated virus vector in a rat arthritis model | Q33645324 | ||
| Meniscal substitutes--animal experience | Q33668951 | ||
| Suppression of intra-articular responses to interleukin-1 by transfer of the interleukin-1 receptor antagonist gene to synovium | Q45867108 | ||
| Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1. | Q45867720 | ||
| IL-1ra/IGF-1 gene therapy modulates repair of microfractured chondral defects | Q45868494 | ||
| Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model | Q45868543 | ||
| Gene therapy for meniscal injury: enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGFbeta(1)gene | Q45869372 | ||
| Clinical research. Death prompts a review of gene therapy vector | Q45869963 | ||
| Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-kappaBp65-specific siRNA. | Q45870090 | ||
| Cartilage and bone regeneration using gene-enhanced tissue engineering | Q45871754 | ||
| Clinical trials in the gene therapy of arthritis | Q45871812 | ||
| In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament | Q45873283 | ||
| Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function | Q45874375 | ||
| NIH recombinant DNA Advisory Committee continues to ponder adverse event associated with AAV gene therapy trial | Q45875459 | ||
| High-efficiency non-viral transfection of primary chondrocytes and perichondrial cells for ex-vivo gene therapy to repair articular cartilage defects | Q45876295 | ||
| Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy. | Q45876579 | ||
| Repair of full-thickness articular cartilage defects by cultured mesenchymal stem cells transfected with the transforming growth factor beta1 gene | Q45877293 | ||
| Gene transfer to the rabbit patellar tendon: potential for genetic enhancement of tendon and ligament healing | Q45880238 | ||
| Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation | Q45880338 | ||
| Continuous transforming growth factor beta1 secretion by cell-mediated gene therapy maintains chondrocyte redifferentiation | Q45881603 | ||
| Gene therapy may be up to speed for cheats at 2008 Olympics | Q45881984 | ||
| In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy | Q45882179 | ||
| Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). | Q45882616 | ||
| Direct retrovirus-mediated gene transfer to the synovium of the rabbit knee: implications for arthritis gene therapy | Q45884087 | ||
| Formation of vascularized meniscal tissue by combining gene therapy with tissue engineering | Q45884142 | ||
| Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis | Q45884566 | ||
| Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. | Q45885266 | ||
| Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia | Q45886388 | ||
| rAAV-mediated overexpression of FGF-2 promotes cell proliferation, survival, and alpha-SMA expression in human meniscal lesions | Q45887301 | ||
| Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats. | Q45887560 | ||
| Adenovirus mediated gene delivery to the joints of guinea pigs. | Q45889116 | ||
| Application of tissue-engineered cartilage with BMP-7 gene to repair knee joint cartilage injury in rabbits | Q45889212 | ||
| Liver-directed gene transfer: a linear polyethlenimine derivative mediates highly efficient DNA delivery to primary hepatocytes in vitro and in vivo | Q45890367 | ||
| Platelet derived growth factor-AB enhances knee meniscal cell activity in vitro | Q46270288 | ||
| Meniscal repair supplemented with exogenous fibrin clot and autogenous cultured marrow cells in the goat model | Q46334309 | ||
| Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo. | Q46383994 | ||
| Different behavior of meniscal cells in collagen II/I,III and Hyaff-11 scaffolds in vitro | Q46636695 | ||
| Development and characterization of an acellular porcine medial meniscus for use in tissue engineering | Q46679423 | ||
| Effects of growth factors on meniscal fibrochondrocytes | Q46688943 | ||
| Towards tissue engineering of meniscus substitutes: selection of cell source and culture environment | Q46942506 | ||
| Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow. | Q47370664 | ||
| Effect on tissue differentiation and articular cartilage degradation of a polymer meniscus implant: A 2-year follow-up study in dogs | Q47422681 | ||
| Transplantation of meniscus regenerated by tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow | Q47444654 | ||
| Comparison of the collagen meniscus implant with partial meniscectomy. A prospective randomized trial | Q47600882 | ||
| Effects of selected growth factors on porcine meniscus in chemically defined medium. | Q47665934 | ||
| Tissue engineering for total meniscal substitution: animal study in sheep model | Q47685574 | ||
| Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. | Q48032598 | ||
| The influence of the stable expression of BMP2 in fibrin clots on the remodelling and repair of osteochondral defects. | Q50454505 | ||
| Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes. | Q50486810 | ||
| Transfer of lacZ marker gene to the meniscus. | Q50517557 | ||
| Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-beta 1 complementary deoxyribonucleic acid. | Q50677733 | ||
| Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells. | Q50752953 | ||
| Meniscal regeneration or meniscal transplantation? | Q33668964 | ||
| Building a meniscus. Biologic considerations | Q33765036 | ||
| Biomechanical factors in tissue engineered meniscal repair | Q33765042 | ||
| Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis | Q33791993 | ||
| Gene transfer to human joints: progress toward a gene therapy of arthritis | Q33853972 | ||
| Gene transfer and athletics- an impending problem | Q33951542 | ||
| Tissue engineering meniscus: cells and matrix | Q33959534 | ||
| Growth factor effects on costal chondrocytes for tissue engineering fibrocartilage | Q33993954 | ||
| Chondrogenitor cells and gene therapy. | Q34064864 | ||
| Using gene therapy to protect and restore cartilage | Q34064867 | ||
| Gene therapy for autoimmune disorders | Q34070348 | ||
| Ethics. Gene doping and sport | Q34097012 | ||
| Adenoviral-mediated gene transfer to rabbit synovium in vivo. | Q34172735 | ||
| Meniscal allografts--where do we stand? | Q34211563 | ||
| Toward tissue engineering of the knee meniscus | Q34220260 | ||
| Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. | Q34345061 | ||
| Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer | Q34345395 | ||
| Matrices for cartilage repair. | Q34403198 | ||
| Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB. | Q34474493 | ||
| Gene therapy in rheumatic diseases | Q34506549 | ||
| Cell-based resurfacing of large cartilage defects: long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis | Q34587806 | ||
| Meniscal injury: II. Management | Q34664038 | ||
| Meniscal transplantation. | Q34672008 | ||
| Meniscus transplantation: current concepts. | Q34781423 | ||
| Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage. | Q34809992 | ||
| Gene therapy and tissue engineering for sports medicine | Q35049984 | ||
| Stem cells as platforms for delivery of genes to enhance cartilage repair. | Q35117290 | ||
| Gene therapy for arthritis | Q35122176 | ||
| Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage | Q35240986 | ||
| Patellofemoral osteoarthritis coexistent with tibiofemoral osteoarthritis in a meniscectomy population | Q35555082 | ||
| Human, viral or mutant human IL-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis | Q35605628 | ||
| Tissue engineering of the meniscus | Q35617353 | ||
| Osteoarthritis gene therapy | Q35629588 | ||
| Mesenchymal stem cells: clinical applications and biological characterization. | Q35686355 | ||
| Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation | Q35766628 | ||
| The strength of the menisci of the knee as it relates to their fine structure | Q71567312 | ||
| Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate | Q71715053 | ||
| Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus | Q71800768 | ||
| Regional mitogenic response of the meniscus to platelet-derived growth factor (PDGF-AB) | Q72170461 | ||
| Transcriptional suppression by interleukin-1 and interferon-gamma of type II collagen gene expression in human chondrocytes | Q72288076 | ||
| Meniscal repair enhanced by an interpositional free synovial autograft: an experimental study in rabbits | Q72606115 | ||
| Induction of meniscal regeneration in dogs using a novel biomaterial | Q73017759 | ||
| Free synovium promotes meniscal healing. Synovium, muscle and synthetic mesh compared in dogs | Q73125876 | ||
| Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study | Q73307734 | ||
| Meniscal tissue regeneration using a collagenous biomaterial derived from porcine small intestine submucosa | Q73427236 | ||
| Delamination rates of tissue flaps used in articular cartilage repair | Q73472322 | ||
| On the mechanism of protection of distal joints after local gene transfer in collagen-induced arthritis | Q73657661 | ||
| The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage | Q73899667 | ||
| Histological analysis of human meniscal allografts. A preliminary report | Q74210963 | ||
| Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer | Q74384610 | ||
| Articular cartilage repair. Rabbit experiments with a collagen gel-biomatrix and chondrocytes cultured in it | Q74387473 | ||
| Gene therapy for rheumatoid arthritis | Q74431392 | ||
| Osteogenic protein (OP-1, BMP-7) stimulates cartilage differentiation of human and goat perichondrium tissue in vitro | Q74583069 | ||
| Transplantation of allograft chondrocytes embedded in agarose gel into cartilage defects of rabbits | Q74620998 | ||
| The menisci of the knee joint. Anatomical and functional characteristics, and a rationale for clinical treatment | Q77596753 | ||
| Genetic engineering of meniscal allografts | Q77748618 | ||
| Beneficial effect of basic fibroblast growth factor on the repair of full-thickness defects in rabbit articular cartilage | Q77957320 | ||
| [In vitro transduction of human osteoblast cell populations with retroviral vectors] | Q78006431 | ||
| Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites | Q78165069 | ||
| Intraarticular gene transfer of TNFR:Fc suppresses experimental arthritis with reduced systemic distribution of the gene product | Q78709124 | ||
| [Gene therapy in orthopaedic surgery] | Q79295118 | ||
| Gene doping | Q80344404 | ||
| [Meniscus replacement: current aspects in the field of tissue engineering] | Q80838370 | ||
| Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2 | Q80931371 | ||
| Stimulation of chondrocytes in vitro by gene transfer with plasmids coding for epidermal growth factor (hEGF) and basic fibroblast growth factor (bFGF) | Q81007882 | ||
| Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo | Q81051748 | ||
| Long-term outcome for large meniscal defects treated with small intestinal submucosa in a dog model | Q81203322 | ||
| Co-transfection with the osteogenic protein (OP)-1 gene and the insulin-like growth factor (IGF)-I gene enhanced osteoblastic cell differentiation | Q81644399 | ||
| Effects of hepatocyte growth factor and platelet-derived growth factor on the repair of meniscal defects in vitro | Q82246995 | ||
| Cartilage repair using bone morphogenetic protein 4 and muscle-derived stem cells | Q82424413 | ||
| Blocking VEGF as a potential approach to improve cartilage healing after osteoarthritis | Q83194937 | ||
| Meniscal allograft transplantation | Q83519984 | ||
| Effects of growth factors on equine synovial fibroblasts seeded on synthetic scaffolds for avascular meniscal tissue engineering | Q84498634 | ||
| Enhanced meniscal repair by overexpression of hIGF-1 in a full-thickness model | Q37411140 | ||
| Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. | Q37453892 | ||
| Meniscal allograft transplantation: a review of the current literature | Q37466792 | ||
| Clinical practice guidelines for the management of meniscal lesions and isolated lesions of the anterior cruciate ligament of the knee in adults | Q37595824 | ||
| Anatomy and physical examination of the knee menisci: a narrative review of the orthopedic literature | Q37663589 | ||
| The basic science of the subchondral bone | Q37684848 | ||
| Disease-specific clinical problems associated with the subchondral bone. | Q37691291 | ||
| The ultrastructure and biochemistry of meniscal cartilage | Q38141491 | ||
| Joint resurfacing using allograft chondrocytes and synthetic biodegradable polymer scaffolds. | Q38570593 | ||
| A system for grading articular cartilage lesions at arthroscopy | Q38693215 | ||
| Meniscal allograft transplantation: long-term clinical results with radiological and magnetic resonance imaging correlations | Q39355329 | ||
| Adeno-associated virus-2-mediated bFGF gene transfer to digital flexor tendons significantly increases healing strength. an in vivo study | Q39844988 | ||
| An acellular, allograft-derived meniscus scaffold in an ovine model | Q39858476 | ||
| Development of serum-free, chemically defined conditions for human embryonic stem cell-derived fibrochondrogenesis | Q39881549 | ||
| Generation and characterization of a human acellular meniscus scaffold for tissue engineering. | Q40029940 | ||
| Tendon healing in vitro: bFGF gene transfer to tenocytes by adeno-associated viral vectors promotes expression of collagen genes | Q40365915 | ||
| Tenascin in connective tissue development and pathogenesis | Q40396759 | ||
| The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage | Q40495139 | ||
| Promoting the proliferative and synthetic activity of knee meniscal fibrochondrocytes using basic fibroblast growth factor in vitro | Q40509590 | ||
| The cryptic life style of adeno-associated virus | Q40524042 | ||
| Growth factor actions on articular cartilage | Q40526506 | ||
| Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene | Q40659435 | ||
| Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapy | Q40698997 | ||
| Light-activated gene transduction enhances adeno-associated virus vector-mediated gene expression in human articular chondrocytes | Q40707011 | ||
| Spontaneous repair of full-thickness defects of articular cartilage in a goat model. A preliminary study | Q40724069 | ||
| Increased life span of human osteoarthritic chondrocytes by exogenous expression of telomerase | Q40741724 | ||
| Evaluation of gene therapy as a treatment for equine traumatic arthritis and osteoarthritis. | Q40742837 | ||
| Functional genomic analysis of type II IL-1beta decoy receptor: potential for gene therapy in human arthritis and inflammation | Q40753102 | ||
| In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression | Q40814456 | ||
| Adeno-associated virus production of soluble tumor necrosis factor receptor neutralizes tumor necrosis factor alpha and reduces arthritis | Q40839721 | ||
| Meniscal allografts. | Q40868416 | ||
| Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis | Q40923547 | ||
| Porous polymer implant for repair of meniscal lesions: a preliminary study in dogs | Q41139644 | ||
| Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector | Q41364483 | ||
| Ultrastructure of adult human articular cartilage matrix after cryotechnical processing | Q41499360 | ||
| Meniscal regeneration with copolymeric collagen scaffolds. In vitro and in vivo studies evaluated clinically, histologically, and biochemically | Q41839965 | ||
| Extraction techniques for the decellularization of tissue engineered articular cartilage constructs | Q42082267 | ||
| Chondrocyte apoptosis induced by nitric oxide | Q42192844 | ||
| Cell culture of rabbit meniscal fibrochondrocytes: proliferative and synthetic response to growth factors and ascorbate | Q42435177 | ||
| Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach | Q42438194 | ||
| Presence of cartilage-derived morphogenetic proteins in articular cartilage and enhancement of matrix replacement in vitro | Q42451491 | ||
| Stable transfection of human fetal chondrocytes with a type II procollagen minigene: expression of the mutant protein and alterations in the structure of the extracellular matrix in vitro | Q42813414 | ||
| Analysis of novel nonviral gene transfer systems for gene delivery to cells of the musculoskeletal system | Q42817730 | ||
| Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts | Q42825494 | ||
| Acceleration of articular cartilage repair by combined gene transfer of human insulin-like growth factor I and fibroblast growth factor-2 in vivo | Q42826063 | ||
| Inducible nonviral gene expression in the treatment of osteochondral defects. | Q42826214 | ||
| Safety, tolerability, and clinical outcomes after intraarticular injection of a recombinant adeno-associated vector containing a tumor necrosis factor antagonist gene: results of a phase 1/2 Study | Q43209177 | ||
| Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study. | Q43632894 | ||
| Gene mediated insulin-like growth factor-I delivery to the synovium | Q43741092 | ||
| Evaluation of small-intestinal submucosa implants for repair of meniscal defects in dogs | Q43930359 | ||
| Menisci are efficiently transduced by recombinant adeno-associated virus vectors in vitro and in vivo | Q44019074 | ||
| Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system | Q44036702 | ||
| Suppression of early experimental osteoarthritis by gene transfer of interleukin-1 receptor antagonist and interleukin-10. | Q44073722 | ||
| Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy | Q44213356 | ||
| Regeneration of whole meniscus using meniscal cells and polymer scaffolds in a rabbit total meniscectomy model | Q44248405 | ||
| Articular cartilage repair by genetically modified bone marrow aspirate in sheep. | Q44292310 | ||
| RAC reviews serious adverse event associated with AAV therapy trial | Q44304216 | ||
| Development of an artificial meniscus using polyvinyl alcohol-hydrogel for early return to, and continuance of, athletic life in sportspersons with severe meniscus injury. II: animal experiments | Q44370020 | ||
| Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer | Q44606527 | ||
| Insulinlike growth factor-I gene therapy applications for cartilage repair. | Q44681640 | ||
| Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation | Q44773219 | ||
| Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation | Q44869190 | ||
| Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9. | Q44912353 | ||
| Meniscus reconstruction through coculturing meniscus cells with synovium-derived stem cells on small intestine submucosa--a pilot study to engineer meniscus tissue constructs | Q44949225 | ||
| Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium. | Q44956168 | ||
| Maturation and integration of tissue-engineered cartilages within an in vitro defect repair model. | Q44986770 | ||
| Combined effects of growth factors and static mechanical compression on meniscus explant biosynthesis | Q45027555 | ||
| Human skeletal muscle cells in ex vivo gene therapy to deliver bone morphogenetic protein-2. | Q45058349 | ||
| Regional regenerative potential of meniscal cartilage exposed to recombinant insulin-like growth factor-I in vitro | Q45077204 | ||
| Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo | Q45127736 | ||
| Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model | Q45193468 | ||
| Gene delivery to cartilage defects using coagulated bone marrow aspirate | Q45252422 | ||
| Meniscal replacement using a cryopreserved allograft. An experimental study in the dog. | Q45355244 | ||
| Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector | Q45421093 | ||
| Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector | Q45527212 | ||
| Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells | Q45703658 | ||
| Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage | Q45728584 | ||
| Gene marking in adeno-associated virus vector infected periosteum derived cells for cartilage repair | Q45730503 | ||
| Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis | Q45731652 | ||
| Gene delivery to human chondrocytes by an adeno associated virus vector | Q45742821 | ||
| Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist | Q45744151 | ||
| Molecular lysis of synovial lining cells by in vivo herpes simplex virus-thymidine kinase gene transfer | Q45752073 | ||
| Adeno-associated virus-mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primates | Q45753061 | ||
| In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes | Q45762980 | ||
| Muscle derived, cell based ex vivo gene therapy for treatment of full thickness articular cartilage defects | Q45854941 | ||
| Gene therapy for rheumatic diseases | Q45855770 | ||
| Ex vivo gene delivery of IL-1Ra and soluble TNF receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis | Q45855957 | ||
| Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: the use of different viral vectors and the effects of injury | Q45856858 | ||
| Co-expression of insulin-like growth factor-1 and interleukin-4 in an in vitro inflammatory model | Q45857253 | ||
| Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix | Q45857330 | ||
| Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair | Q45858190 | ||
| Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection | Q45858296 | ||
| Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells | Q45858313 | ||
| Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells | Q45858451 | ||
| Adenovirus-mediated gene therapy of osteoblasts in vitro and in vivo | Q45861695 | ||
| Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency | Q45861880 | ||
| Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium | Q45862612 | ||
| Anti-apoptotic Bcl-2 gene transfection of human articular chondrocytes protects against nitric oxide-induced apoptosis | Q45864334 | ||
| Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair | Q45866522 | ||
| Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis. | Q45867090 | ||
| The effect of locally applied vascular endothelial growth factor on meniscus healing: gross and histological findings. | Q51149465 | ||
| Regeneration of whole meniscus using meniscal cells and polymer scaffolds in a rabbit total meniscectomy model. | Q51254294 | ||
| Replacement of the knee meniscus by a porous polymer implant: a study in dogs. | Q51327611 | ||
| Growth factors and fibrochondrocytes in scaffolds. | Q51360853 | ||
| Tissue-engineered collagen meniscus implants: 5- to 6-year feasibility study results. | Q51468104 | ||
| Healing of a chondral fragment of the knee in an adolescent after internal fixation. A case report. | Q51568773 | ||
| Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study. | Q51761544 | ||
| Effects of co-cultures of meniscus cells and articular chondrocytes on PLLA scaffolds. | Q51775506 | ||
| Recombinant human growth/differentiation factor 5 stimulates mesenchyme aggregation and chondrogenesis responsible for the skeletal development of limbs. | Q52203438 | ||
| The gene for the homeodomain-containing protein Cart-1 is expressed in cells that have a chondrogenic potential during embryonic development. | Q52212566 | ||
| The influence of transforming growth factor beta1 on mesenchymal cell repair of full-thickness cartilage defects. | Q52969270 | ||
| Tissue engineered cartilage repair using cryopreserved and noncryopreserved chondrocytes. | Q52969700 | ||
| Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapy | Q53528538 | ||
| Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells. | Q53614868 | ||
| Vital marking of articular chondrocytes by retroviral infection using green fluorescence protein. | Q53878084 | ||
| In vivo gene delivery to synovium by lentiviral vectors. | Q53974167 | ||
| Use of porous polyurethanes for meniscal reconstruction and meniscal prostheses. | Q54154115 | ||
| [Role of synovial inflammation, cytokines and IGF-1 in the physiopathology of osteoarthritis] | Q54191153 | ||
| Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7. | Q54523709 | ||
| Transplantation of adenovirally transduced allogeneic chondrocytes into articular cartilage defects in vivo. | Q54562484 | ||
| Basic fibroblast growth factor stimulates articular cartilage enlargement in young rats in vivo. | Q54596442 | ||
| Meniscal transplantation in the human knee: A preliminary report | Q56805853 | ||
| Articular cartilage repair in rabbits by using suspensions of allogenic chondrocytes in alginate | Q57188808 | ||
| Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent | Q57539923 | ||
| Tissue-engineered composites for the repair of large osteochondral defects | Q59125446 | ||
| Vascular endothelial growth factor (VEGF) gene transfer enhances surgical revascularization of necrotic bone | Q59703709 | ||
| Intraarticular gene transfer of thrombospondin-1 suppresses the disease progression of experimental osteoarthritis | Q64374958 | ||
| Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis | Q64377272 | ||
| Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9 | Q64377343 | ||
| Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4 | Q64380123 | ||
| Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints | Q64380286 | ||
| Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes | Q64380332 | ||
| Ex vivo gene delivery using an adenovirus vector in treatment for cartilage defects | Q64380810 | ||
| Viral IL-10 and soluble TNF receptor act synergistically to inhibit collagen-induced arthritis following adenovirus-mediated gene transfer | Q64381028 | ||
| Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees | Q64381356 | ||
| In vivo gene transfer and overexpression of focal adhesion kinase (pp125 FAK) mediated by recombinant adenovirus-induced tendon adhesion formation and epitenon cell change | Q64382168 | ||
| [Virally mediated gene transfer in the patellar tendon. An experimental study in rabbits] | Q64382420 | ||
| Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo | Q64382873 | ||
| Characterization of a Specific Somatomedin-C Receptor on Isolated Bovine Growth Plate Chondrocytes* | Q67294034 | ||
| [Significance of shape differences between medial and lateral knee joint menisci for functional change of position] | Q67818205 | ||
| Cellular repopulation of deep-frozen meniscal autografts: an experimental study in the dog | Q67967538 | ||
| Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide | Q68261503 | ||
| Meniscal repair using an exogenous fibrin clot. An experimental study in dogs | Q68506663 | ||
| Microvasculature of the human meniscus | Q70363118 | ||
| Regulation of growth-plate chondrocytes by insulin-like growth-factor I and basic fibroblast growth factor | Q70536378 | ||
| Cell origin and differentiation in the repair of full-thickness defects of articular cartilage | Q70671226 | ||
| A bovine brain fraction with fibroblast growth factor activity inducing articular cartilage regeneration in vivo | Q70929481 | ||
| Nanoparticle-mediated gene delivery: state of the art. | Q35842597 | ||
| The 2003 Nicolas Andry Award. Orthopaedic gene therapy. | Q35970992 | ||
| Gene therapy: what have we accomplished and where do we go from here? | Q36014551 | ||
| Tissue engineering for meniscus repair. | Q36059550 | ||
| Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur | Q36223123 | ||
| Gene therapy for the treatment of musculoskeletal diseases. | Q36236529 | ||
| Gene therapy for cartilage defects | Q36249170 | ||
| Locally applied angiogenic factors--a new therapeutic tool for meniscal repair | Q36328008 | ||
| Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects | Q36477567 | ||
| Gene therapy for arthritis: what next? | Q36490241 | ||
| Current concepts in gene therapy of the musculoskeletal system. | Q36492611 | ||
| Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation | Q36535001 | ||
| Application of cellular gene therapy for rheumatoid arthritis | Q36622653 | ||
| Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector | Q36663364 | ||
| Cellular engineering | Q36784250 | ||
| Arthritis gene therapy's first death | Q36790320 | ||
| Potential use of gene transfer in athletic performance enhancement. | Q36902844 | ||
| Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1. | Q36934659 | ||
| Developing strategies for detection of gene doping. | Q37032504 | ||
| Liposomes in biology and medicine | Q37064167 | ||
| Meniscal repair | Q37237322 | ||
| Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery | Q37249023 | ||
| Meniscus replacement using synthetic materials | Q37343803 | ||
| Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: The Multicenter Osteoarthritis Study | Q37378387 | ||
| Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model | Q37383110 | ||
| Meniscus tissue engineering on the nanoscale: from basic principles to clinical application | Q37392718 | ||
| Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome | Q37411118 | ||
| P433 | issue | 3 | |
| P921 | main subject | gene therapy | Q213901 |
| cartilage | Q502730 | ||
| P304 | page(s) | 201-225 | |
| P577 | publication date | 2011-07-01 | |
| P1433 | published in | Cartilage | Q5047348 |
| P1476 | title | Gene Therapy for Cartilage Repair | |
| P478 | volume | 2 |
| Q92994177 | A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues |
| Q38134331 | Advances and challenges in gene-based approaches for osteoarthritis |
| Q34225355 | Biological aspects of early osteoarthritis |
| Q42413507 | Cartilage constructs engineered from chondrocytes overexpressing IGF-I improve the repair of osteochondral defects in a rabbit model. |
| Q37960493 | Cartilage repair and joint preservation: medical and surgical treatment options |
| Q40479463 | Comparison of Efficacy of Endogenous and Exogenous IGF-I in Stimulating Matrix Production in Neonatal and Mature Chondrocytes. |
| Q38707730 | Current clinical evidence for the use of mesenchymal stem cells in articular cartilage repair |
| Q38187403 | Current perspectives in stem cell research for knee cartilage repair |
| Q58701313 | Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part II: treatment options |
| Q33754990 | Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 Pathway |
| Q47817077 | Enamel matrix derivative inhibits proteoglycan production and articular cartilage repair, delays the restoration of the subchondral bone and induces changes of the synovial membrane in a lapine osteochondral defect model in vivo |
| Q38642703 | Gene therapy for human osteoarthritis: principles and clinical translation |
| Q38958292 | Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair |
| Q35981335 | New trends in articular cartilage repair |
| Q45866308 | Nonviral gene transfer to human meniscal cells. Part I: transfection analyses and cell transplantation to meniscus explants |
| Q89746127 | Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery |
| Q38702471 | Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer |
| Q38245621 | Tissue-engineering strategies to repair joint tissue in osteoarthritis: nonviral gene-transfer approaches |
| Q57787477 | Treatment of Articular Cartilage Defects: Focus on Tissue Engineering |
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