Medicinal Chemistry: Insights into the Development of Novel H2S Donors.

scientific article published on January 2015

Medicinal Chemistry: Insights into the Development of Novel H2S Donors. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/978-3-319-18144-8_18
P698PubMed publication ID26162844

P50authorYu ZhaoQ82804403
P2093author name stringMing Xian
Armando Pacheco
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Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in miceQ30497008
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S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditionsQ79419961
Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalationQ80809383
S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathwayQ80980892
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Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiolsQ34032571
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NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse modelQ34256975
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AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitroQ34477537
Hydrogen sulfide protects HUVECs against hydrogen peroxide induced mitochondrial dysfunction and oxidative stressQ34580841
Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms.Q34751757
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Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesisQ35048409
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H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal K(ATP) channelQ37730872
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Prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs), more than meets the eye: a critical reviewQ38068081
Chemical aspects of hydrogen sulfide measurements in physiological samplesQ38114680
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Effects of hydrogen sulfide-releasing L-DOPA derivatives on glial activation: potential for treating Parkinson disease.Q39718802
Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondriaQ39784182
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Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the ratQ42122753
Light-induced hydrogen sulfide release from "caged" gem-dithiols.Q42160193
Pharmacological profile of a novel H(2)S-releasing aspirinQ42804885
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Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats.Q42913506
Diallyl disulfide and diallyl trisulfide protect endothelial nitric oxide synthase against damage by oxidized low-density lipoproteinQ43129743
A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cellsQ44131370
The toxicity of hydrogen sulphide and other sulphidesQ44460706
Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivativeQ44706021
Hydrogen sulfide protects neurons from oxidative stressQ44904699
Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3.Q45061684
A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopaQ45087241
Hydrogen sulphide vasodilates human pulmonary arteries: a possible role in pulmonary hypertension?Q45104314
Role of hydrogen sulfide in acute pancreatitis and associated lung injuryQ45238727
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2.Q45947130
S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway.Q45957950
Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target.Q45970576
Hydrogen sulphide is pro-inflammatory in haemorrhagic shockQ46182818
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouseQ46465914
Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocagesQ46508139
The possible role of hydrogen sulfide as an endogenous neuromodulator.Q46606180
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfideQ46621665
Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injuryQ46626531
Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in miceQ46718598
P304page(s)365-388
P577publication date2015-01-01
P1433published inHandbook of experimental pharmacologyQ26841924
P1476titleMedicinal Chemistry: Insights into the Development of Novel H2S Donors
P478volume230

Reverse relations

cites work (P2860)
Q38658612A Novel Esterase-sensitive Prodrug Approach for Controllable Delivery of Persulfide Species
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Q38806800Hydrogen Sulfide Donors Activated by Reactive Oxygen Species
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Q39152370Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues.
Q39113984Vascular biology of hydrogen sulfide

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