| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1030316689 |
| P356 | DOI | 10.1038/NRC3984 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/nrc3984 |
| P698 | PubMed publication ID | 26383138 |
| P50 | author | Arianna Sabò | Q55168139 |
| Bruno Amati | Q43817846 | ||
| P2093 | author name string | Theresia R Kress | |
| P2860 | cites work | The chromodomain-containing histone acetyltransferase TIP60 acts as a code reader, recognizing the epigenetic codes for initiating transcription | Q86477616 |
| Connecting variability in global transcription rate to mitochondrial variability | Q21092717 | ||
| The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis | Q24293460 | ||
| Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc | Q24294647 | ||
| Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach | Q24297923 | ||
| Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
| Regulation of cyclin D1 RNA stability by SNIP1 | Q24312714 | ||
| Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc | Q24314313 | ||
| SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes | Q24323701 | ||
| MYC recruits the TIP60 histone acetyltransferase complex to chromatin | Q24535721 | ||
| Myc represses transcription through recruitment of DNA methyltransferase corepressor | Q24557458 | ||
| AREsite: a database for the comprehensive investigation of AU-rich elements | Q24607213 | ||
| Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs | Q24609086 | ||
| c-Myc regulates transcriptional pause release | Q24629119 | ||
| Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element | Q24629916 | ||
| RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo | Q24645367 | ||
| Widespread microRNA repression by Myc contributes to tumorigenesis | Q24647067 | ||
| c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL | Q24653312 | ||
| Genomic targets of the human c-Myc protein | Q24672480 | ||
| Global mapping of c-Myc binding sites and target gene networks in human B cells | Q24675083 | ||
| Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 | Q24681460 | ||
| An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets | Q24792966 | ||
| c-MYC-miRNA circuitry: a central regulator of aggressive B-cell malignancies | Q26851373 | ||
| Getting up to speed with transcription elongation by RNA polymerase II | Q27023288 | ||
| Miz-1 activates gene expression via a novel consensus DNA binding motif | Q35199251 | ||
| Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. | Q35204486 | ||
| Taming of the beast: shaping Myc-dependent amplification | Q35235723 | ||
| Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo | Q35260961 | ||
| Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. | Q35267304 | ||
| Premetazoan ancestry of the Myc-Max network | Q35468637 | ||
| MYC activation is a hallmark of cancer initiation and maintenance | Q27026026 | ||
| Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms. | Q27308751 | ||
| X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors | Q27640369 | ||
| c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis | Q28204153 | ||
| Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor | Q28209672 | ||
| Repression of p15INK4b expression by Myc through association with Miz-1 | Q28210023 | ||
| Negative regulation of the mammalian UV response by Myc through association with Miz-1 | Q28212421 | ||
| Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B) | Q28216177 | ||
| E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression | Q28216519 | ||
| c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I | Q28236082 | ||
| Context-dependent control of alternative splicing by RNA-binding proteins | Q28245737 | ||
| Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc | Q28257537 | ||
| Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC | Q28259591 | ||
| Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes | Q28265486 | ||
| An extended transcriptional network for pluripotency of embryonic stem cells | Q28273615 | ||
| An expansive human regulatory lexicon encoded in transcription factor footprints | Q28274429 | ||
| c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells | Q28275988 | ||
| Non-transcriptional control of DNA replication by c-Myc | Q28307758 | ||
| CpG islands and the regulation of transcription | Q28315762 | ||
| The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding | Q28567657 | ||
| A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism | Q28581419 | ||
| Myc deletion rescues Apc deficiency in the small intestine | Q28591197 | ||
| Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis | Q28593886 | ||
| Overexpression of the c-myc oncogene inhibits nonsense-mediated RNA decay in B lymphocytes | Q28742550 | ||
| Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma | Q28742928 | ||
| Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans | Q29394946 | ||
| Stat3 as an oncogene | Q29614606 | ||
| The many pathways of RNA degradation | Q29615760 | ||
| Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
| c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism | Q29617213 | ||
| MYC on the path to cancer | Q29619979 | ||
| Myc and its interactors take shape. | Q30363660 | ||
| Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1 | Q30480348 | ||
| Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc | Q30886084 | ||
| Global regulation of nucleotide biosynthetic genes by c-Myc | Q33352002 | ||
| Global target mRNA specification and regulation by the RNA-binding protein ZFP36. | Q33741987 | ||
| Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming | Q35486433 | ||
| The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements. | Q35573905 | ||
| myc function and regulation | Q35671084 | ||
| The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation | Q35736854 | ||
| Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells | Q35761146 | ||
| Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. | Q35882709 | ||
| Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network | Q35965143 | ||
| Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants | Q36142180 | ||
| Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state | Q36174961 | ||
| Transcriptional regulation and transformation by Myc proteins | Q36215755 | ||
| c-Myc transactivation of LDH-A: implications for tumor metabolism and growth | Q36238451 | ||
| Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition. | Q36288668 | ||
| MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression | Q36326252 | ||
| Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc | Q36398127 | ||
| MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase | Q36545376 | ||
| An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants | Q36550858 | ||
| An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc | Q36561988 | ||
| The Myc oncoprotein as a therapeutic target for human cancer | Q36578165 | ||
| Conditional transgenic models define how MYC initiates and maintains tumorigenesis | Q36578360 | ||
| c-Myc enhances protein synthesis and cell size during B lymphocyte development | Q36668198 | ||
| Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A | Q36850429 | ||
| Feedback regulation of c-Myc by ribosomal protein L11 | Q37011222 | ||
| The c-myc promoter: still MysterY and challenge | Q37013896 | ||
| MYC, metabolism, cell growth, and tumorigenesis. | Q37040243 | ||
| Cellular MYCro economics: Balancing MYC function with MYC expression | Q37256438 | ||
| Myc's broad reach | Q37299032 | ||
| Reflecting on 25 years with MYC. | Q37333643 | ||
| MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation | Q37485846 | ||
| c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation | Q37620912 | ||
| Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations | Q37638159 | ||
| Bim is a suppressor of Myc-induced mouse B cell leukemia | Q37647369 | ||
| The eukaryotic RNA exosome | Q37700949 | ||
| MYC as a regulator of ribosome biogenesis and protein synthesis | Q37718002 | ||
| Transcriptional repression: the dark side of myc. | Q37903692 | ||
| Medulloblastoma growth inhibition by hedgehog pathway blockade | Q44119270 | ||
| Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? | Q46090320 | ||
| Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation | Q46487258 | ||
| Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis | Q46843790 | ||
| Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. | Q50777362 | ||
| P-TEFb is a crucial co-factor for Myc transactivation. | Q51578626 | ||
| Drosophila myc regulates cellular growth during development. | Q52573250 | ||
| Myc function in Drosophila. | Q52760873 | ||
| Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis. | Q53346701 | ||
| Ras and Myc can drive oncogenic cell proliferation through individual D-cyclins. | Q53355278 | ||
| Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. | Q53399561 | ||
| Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis | Q53571550 | ||
| The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice | Q57338720 | ||
| Mammalian MYC Proteins and Cancer | Q59072385 | ||
| Immunologic competence of B cells subjected to constitutive c-myc oncogene expression in immunoglobulin heavy chain enhancer myc transgenic mice | Q59607111 | ||
| New cell cycle compartments identified by multiparameter flow cytometry | Q62590675 | ||
| Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes | Q73428241 | ||
| Myc requires distinct E2F activities to induce S phase and apoptosis | Q74394147 | ||
| Sustained loss of a neoplastic phenotype by brief inactivation of MYC | Q74413944 | ||
| Determination of copy number of c-Myc protein per cell by quantitative Western blotting | Q74644736 | ||
| A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition | Q79773933 | ||
| Miz1 is required to maintain autophagic flux. | Q33854521 | ||
| Reversible tumorigenesis by MYC in hematopoietic lineages | Q33874286 | ||
| The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance | Q33913197 | ||
| mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E | Q33938526 | ||
| Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. | Q33948902 | ||
| Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome | Q34034406 | ||
| Control of transcriptional elongation | Q34038245 | ||
| Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29 | Q34055226 | ||
| Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation | Q34062305 | ||
| c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells | Q34071196 | ||
| Endogenous Myc maintains the tumor microenvironment | Q34177033 | ||
| The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation | Q34242691 | ||
| Myc-dependent mitochondrial generation of acetyl-CoA contributes to fatty acid biosynthesis and histone acetylation during cell cycle entry | Q34298938 | ||
| Transcriptional amplification in tumor cells with elevated c-Myc. | Q34302542 | ||
| The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation | Q34308263 | ||
| Revisiting global gene expression analysis | Q34308389 | ||
| CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma | Q34342934 | ||
| MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer | Q34357796 | ||
| CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. | Q34449062 | ||
| The spliceosome is a therapeutic vulnerability in MYC-driven cancer | Q34492012 | ||
| Sequence specificity incompletely defines the genome-wide occupancy of Myc. | Q34565509 | ||
| NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth | Q34582832 | ||
| Myc influences global chromatin structure. | Q34766868 | ||
| Modelling Myc inhibition as a cancer therapy | Q34811008 | ||
| Drosophila Myc: A master regulator of cellular performance | Q34873737 | ||
| c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma | Q34958884 | ||
| Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. | Q35027765 | ||
| Emerging landscape of oncogenic signatures across human cancers | Q35058708 | ||
| Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis | Q35079601 | ||
| Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing. | Q35097988 | ||
| Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc | Q35131413 | ||
| MYC regulates the non-coding transcriptome. | Q35149681 | ||
| Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters | Q35158848 | ||
| Coordinating genome expression with cell size | Q38032012 | ||
| Nonsense-mediated mRNA decay - mechanisms of substrate mRNA recognition and degradation in mammalian cells | Q38084065 | ||
| Genome recognition by MYC. | Q38184910 | ||
| MicroRNAs as regulators and mediators of c-MYC function | Q38204153 | ||
| MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis | Q38299040 | ||
| The mechanism of discrimination between cognate and non-specific DNA by dimeric b/HLH/LZ transcription factors | Q38307590 | ||
| Myc-binding-site recognition in the human genome is determined by chromatin context | Q38312447 | ||
| Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. | Q38316206 | ||
| Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). | Q38319947 | ||
| Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis | Q38324237 | ||
| Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression | Q38354644 | ||
| Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction | Q38926653 | ||
| C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells | Q38929791 | ||
| Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles. | Q38973733 | ||
| Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer | Q38992372 | ||
| Transcriptional control of DNA replication licensing by Myc. | Q39048077 | ||
| Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors | Q39283917 | ||
| Oncogenic splicing factor SRSF1 is a critical transcriptional target of MYC. | Q39356444 | ||
| TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b | Q39420254 | ||
| Bax is a transcriptional target and mediator of c-myc-induced apoptosis. | Q39424255 | ||
| Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway. | Q39446946 | ||
| HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer | Q39763266 | ||
| S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation. | Q39791099 | ||
| Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins | Q39959273 | ||
| Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming | Q39960559 | ||
| Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells | Q39996434 | ||
| HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity | Q40136909 | ||
| A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation | Q40350288 | ||
| Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events | Q40387972 | ||
| c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. | Q40456137 | ||
| Direct activation of RNA polymerase III transcription by c-Myc | Q40677362 | ||
| Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. | Q40731052 | ||
| Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells | Q40871821 | ||
| Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency | Q40890351 | ||
| Control of cell growth by c-Myc in the absence of cell division | Q40919064 | ||
| Ras enhances Myc protein stability. | Q40967066 | ||
| c-myc protein expression in untransformed fibroblasts | Q41684755 | ||
| Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation | Q41871917 | ||
| Metabolic regulation of epigenetics | Q41942880 | ||
| c-MYC-induced genomic instability. | Q42127661 | ||
| Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors | Q42262226 | ||
| STAT3 is required for the gp130-mediated full activation of the c-myc gene | Q42753357 | ||
| Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter | Q42811398 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 593-607 | |
| P577 | publication date | 2015-09-18 | |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | MYC: connecting selective transcriptional control to global RNA production | |
| P478 | volume | 15 |
| Q58547071 | A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade |
| Q50905937 | A Time for MYC: Metabolism and Therapy. |
| Q89399700 | A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation |
| Q37419375 | ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC. |
| Q50027280 | AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress. |
| Q90482750 | Advances in targeted therapy for malignant lymphoma |
| Q92162437 | Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer |
| Q49791794 | An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers. |
| Q92114389 | An early Myc-dependent transcriptional program orchestrates cell growth during B-cell activation |
| Q54978916 | Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability. |
| Q36506766 | BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis. |
| Q51416712 | BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141. |
| Q89537434 | Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake |
| Q97906013 | Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis |
| Q56355644 | CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia |
| Q60907680 | CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer |
| Q99557336 | Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw |
| Q37688783 | Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells |
| Q48172655 | Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia |
| Q55000725 | Combination immuno-oncology therapy with immune checkpoint blockers targeting PD-L1, PD-1 or CTLA4 and epigenetic drugs targeting MYC and immune evasion for precision medicine. |
| Q61124716 | Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer |
| Q38756638 | Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors. |
| Q48103411 | Comprehensive network of miRNA-induced intergenic interactions and a biological role of its core in cancer. |
| Q37546242 | Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks |
| Q33608508 | Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling |
| Q41976612 | Correspondence: Reply to 'Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα'. |
| Q92218177 | DAXX in cancer: phenomena, processes, mechanisms and regulation |
| Q52714487 | De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. |
| Q52596648 | Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction. |
| Q54978768 | Developmental vascular regression is regulated by a Wnt/β-catenin, MYC, P21 (CDKN1A) pathway that controls cell proliferation and cell death. |
| Q37131368 | Different promoter affinities account for specificity in MYC-dependent gene regulation. |
| Q50421170 | Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis. |
| Q35873154 | Differentially Expressed Genes and Signature Pathways of Human Prostate Cancer |
| Q97890320 | Dissecting transcriptional amplification by MYC |
| Q36780139 | Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1. |
| Q55481081 | Downregulation of ribosome biogenesis during early forebrain development. |
| Q42320410 | Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis |
| Q36148000 | E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell Proliferation |
| Q59351258 | Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERαY537S and ERαD538G mutations |
| Q60300456 | Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells |
| Q58797685 | FBXW7: a critical tumor suppressor of human cancers |
| Q52714441 | FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome. |
| Q64111281 | Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation |
| Q58108213 | Focal adhesion kinase activation limits efficacy of Dasatinib in c-Myc driven hepatocellular carcinoma |
| Q36473639 | Functional divergence and convergence between the transcript network and gene network in lung adenocarcinoma |
| Q38778174 | Functionally diverse human T cells recognize non-microbial antigens presented by MR1. |
| Q58551710 | Gastric Cancer Cell Lines Have Different -Regulated Expression Patterns but Share a Common Core of Altered Genes |
| Q38808728 | Gene therapy as a potential tool for treating neuroblastoma-a focused review |
| Q64040347 | Gene-Specific Intron Retention Serves as Molecular Signature that Distinguishes Melanoma from Non-Melanoma Cancer Cells in Greek Patients |
| Q37435041 | Highly expressed ribosomal protein L34 indicates poor prognosis in osteosarcoma and its knockdown suppresses osteosarcoma proliferation probably through translational control |
| Q56335042 | Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer |
| Q64054212 | IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis |
| Q37746816 | In vivo Reprogramming of Cancer Metabolism by MYC. |
| Q36368265 | Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma. |
| Q40082486 | Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma |
| Q42275753 | Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation. |
| Q54111513 | Interleukin-1β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis. |
| Q64091307 | Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy |
| Q47099797 | LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells |
| Q93129629 | LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis |
| Q64060619 | Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm |
| Q89477862 | Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription |
| Q92743284 | Long non-coding RNA ARAP1-AS1 promotes tumorigenesis and metastasis through facilitating proto-oncogene c-Myc translation via dissociating PSF/PTB dimer in cervical cancer |
| Q38625813 | Lysine-52 stabilizes the MYC oncoprotein through an SCF(Fbxw7)-independent mechanism |
| Q33557724 | MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma |
| Q39147902 | MNT and Emerging Concepts of MNT-MYC Antagonism |
| Q67483657 | MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming. |
| Q37014197 | MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer |
| Q39406924 | MYC Modulation around the CDK2/p27/SKP2 Axis |
| Q64269432 | MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation |
| Q88330781 | MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition |
| Q48588758 | MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels. |
| Q39262984 | MYC and AMPK-Save Energy or Die! |
| Q64990074 | MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. |
| Q47414931 | MYC and tumor metabolism: chicken and egg. |
| Q58327191 | MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability |
| Q39306981 | MYC-Master Regulator of the Cancer Epigenome and Transcriptome |
| Q45742884 | MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21. |
| Q40065267 | Metabolism in Immune Cell Differentiation and Function. |
| Q38696414 | MiR-376a suppresses the proliferation and invasion of non-small-cell lung cancer by targeting c-Myc |
| Q92490663 | Mission Possible: Advances in MYC Therapeutic Targeting in Cancer |
| Q47134903 | Mnt modulates Myc-driven lymphomagenesis |
| Q39028088 | More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer. |
| Q37622098 | Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells. |
| Q64892789 | Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse. |
| Q45325110 | N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly |
| Q38674970 | N-myc regulates growth and fiber cell differentiation in lens development |
| Q39112756 | Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatment |
| Q27728475 | OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors |
| Q51049205 | Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis-A connection to licensing nodes. |
| Q38712433 | Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk |
| Q33688490 | Over-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancer |
| Q52723228 | Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. |
| Q40996455 | Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc |
| Q92691115 | Pluripotency and the origin of animal multicellularity |
| Q58114009 | Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals |
| Q36278557 | Potential effect of spliceosome inhibition in small cell lung cancer irrespective of the MYC status |
| Q91857984 | Primary transcripts: From the discovery of RNA processing to current concepts of gene expression - Review |
| Q88582153 | Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element |
| Q52731173 | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. |
| Q89720844 | RBP EIF2S2 Promotes Tumorigenesis and Progression by Regulating MYC-Mediated Inhibition via FHIT-Related Enhancers |
| Q47786398 | RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions |
| Q91891691 | Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity |
| Q59128687 | Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis |
| Q99616637 | Recent advances in the development of protein-protein interactions modulators: mechanisms and clinical trials |
| Q37188977 | SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells. |
| Q67199191 | SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis |
| Q57286305 | SUMO protease SENP1 deSUMOylates and stabilizes c-Myc |
| Q38696935 | Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs. |
| Q40340005 | Sox2-dependent inhibition of p21 is associated with poor prognosis of endometrial cancer. |
| Q31814812 | Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors |
| Q55177532 | Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma. |
| Q58170280 | Synthetic molecules for disruption of the MYC protein-protein interface |
| Q37317046 | TEAD activity is restrained by MYC and stratifies human breast cancer subtypes. |
| Q47370876 | TGF-β-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC. |
| Q58087056 | TXNDC9 promotes hepatocellular carcinoma progression by positive regulation of MYC-mediated transcriptional network |
| Q89767723 | Target gene-independent functions of MYC oncoproteins |
| Q91750656 | Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors |
| Q36762189 | Targeting MYC in cancer therapy: RNA processing offers new opportunities |
| Q87842402 | Targeting MYC in multiple myeloma |
| Q100750298 | Targeting c-Myc with a novel Peptide Nuclear Delivery Device |
| Q47337952 | Targeting oncoproteins for degradation by small molecules in myeloid leukemia. |
| Q55137359 | Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity. |
| Q89665733 | The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein |
| Q90320875 | The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number |
| Q93333197 | The MYC Enhancer-ome: Long-Range Transcriptional Regulation of MYC in Cancer |
| Q38707758 | The MYC mRNA 3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels. |
| Q90583377 | The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis |
| Q89944283 | The Role of MYC and PP2A in the Initiation and Progression of Myeloid Leukemias |
| Q41335662 | The cohesin complex prevents Myc-induced replication stress. |
| Q41612126 | The establishment of a growth-controllable orthotopic bladder cancer model through the down-regulation of c-myc expression |
| Q46275180 | The maternal-zygotic transition and zygotic activation of the Mnemiopsis leidyi genome occurs within the first three cleavage cycles |
| Q42124282 | The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas |
| Q64974084 | The role of circadian clock genes in tumors. |
| Q38882532 | The role of enhancers in cancer |
| Q90093670 | The role of ubiquitination in tumorigenesis and targeted drug discovery |
| Q91011024 | The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia |
| Q47104051 | Transcriptional integration of mitogenic and mechanical signals by Myc and YAP. |
| Q47408311 | Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals |
| Q37131341 | Tuning the MYC response. |
| Q90468288 | UHRF1-KAT7-mediated regulation of TUSC3 expression via histone methylation/acetylation is critical for the proliferation of colon cancer cells |
| Q33597902 | Upregulation of KIN17 is associated with non-small cell lung cancer invasiveness |
| Q90388631 | ZFP281 Recruits MYC to Active Promoters in Regulating Transcriptional Initiation and Elongation |
| Q88550992 | c-MYC amplification and c-myc protein expression in pancreatic acinar cell carcinomas. New insights into the molecular signature of these rare cancers |
| Q64965041 | c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism. |
| Q92380913 | c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma |
| Q41768979 | c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production |
| Q42316813 | c-Myc deregulation induces mRNA capping enzyme dependency. |
| Q90574835 | c-Myc transactivates GP73 and promotes metastasis of hepatocellular carcinoma cells through GP73-mediated MMP-7 trafficking in a mildly hypoxic microenvironment |
| Q52721285 | lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. |
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