Balancing the risks and benefits of biologic therapy in inflammatory bowel diseases.

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Balancing the risks and benefits of biologic therapy in inflammatory bowel diseases. is …
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P356DOI10.1517/14740338.2015.1108961
P698PubMed publication ID26559664

P50authorItishree TrivediQ59703376
P2093author name stringStephen B Hanauer
P2860cites workNatalizumab Induction and Maintenance Therapy for Crohn's DiseaseQ22250890
Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic ReviewQ22250934
Adverse effects of biologics: a network meta-analysis and Cochrane overviewQ24234197
Update on PML and PML-IRIS occurring in multiple sclerosis patients treated with natalizumabQ26851341
Liver injury from tumor necrosis factor-α antagonists: analysis of thirty-four casesQ26864098
Review article: anti-adhesion therapies for inflammatory bowel diseaseQ26999705
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agentQ28191546
Natalizumab for active Crohn's diseaseQ28201431
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trialQ28202504
Differential expression of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in ulcerative colitis and Crohn's diseaseQ28213091
Golimumab for the treatment of ulcerative colitisQ28236322
Certolizumab pegol for the treatment of Crohn's diseaseQ28236746
Infliximab maintenance therapy for fistulizing Crohn's diseaseQ28246982
Adalimumab for the induction and maintenance of clinical remission in Japanese patients with Crohn's diseaseQ48484232
Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trialQ49167560
Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study.Q50898166
Severe infusion reactions to infliximab: aetiology, immunogenicity and risk factors in patients with inflammatory bowel disease.Q51036254
Serum adalimumab concentration and clinical remission in patients with Crohn's disease.Q51069789
Characterization of patients with infliximab-induced lupus erythematosus and outcomes after retreatment with a second anti-TNF agent.Q51553118
Formation, distribution, and elimination of infliximab and anti-infliximab immune complexes in cynomolgus monkeys.Q51554698
Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease.Q51739537
Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial.Q53122367
A randomized placebo-controlled trial of a humanized monoclonal antibody to alpha4 integrin in active Crohn's disease.Q53477555
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.Q53964227
Autoimmune Diseases Induced by TNF-Targeted TherapiesQ56907567
Infliximab, azathioprine, or combination therapy for Crohn's diseaseQ56988763
Infliximab prevents Crohn's disease recurrence after ileal resectionQ57130823
Influence of Trough Serum Levels and Immunogenicity on Long-term Outcome of Adalimumab Therapy in Crohn's DiseaseQ57265393
Comparative Effectiveness of Immunosuppressants and Biologics for Inducing and Maintaining Remission in Crohn's Disease: A Network Meta-analysisQ57910344
Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trialQ59120396
Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitisQ46990369
Work losses related to inflammatory bowel disease in the United States: results from the National Health Interview Survey.Q47827799
Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart FailuQ47849023
Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease: a randomized controlled trial.Q48172806
Costs of care for Crohn's disease following the introduction of infliximab: a single-centre UK experienceQ48314202
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's diseaseQ28255557
Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapiesQ28256960
A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's diseaseQ28270722
Infliximab for induction and maintenance therapy for ulcerative colitisQ28285876
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trialQ28296771
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosisQ29616119
The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and deathQ29620519
Adalimumab maintains remission of Crohn's disease after up to 4 years of treatment: data from CHARM and ADHERE.Q30679247
Review article: non-malignant haematological complications of anti-tumour necrosis factor alpha therapyQ33401933
Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters CommitteeQ33523446
Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysisQ33756929
Infliximab for the treatment of fistulas in patients with Crohn's diseaseQ33860666
The clinical features of PML.Q34085230
Risk of natalizumab-associated progressive multifocal leukoencephalopathyQ34275329
Vedolizumab as induction and maintenance therapy for ulcerative colitisQ34365566
Vedolizumab as induction and maintenance therapy for Crohn's diseaseQ34365574
Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trialQ34431219
A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's diseaseQ34520640
The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patientsQ34544307
Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trialQ34574245
Management of Crohn's disease in adults.Q34931424
Biological agents for moderately to severely active ulcerative colitis: a systematic review and network meta-analysisQ35171236
Efficacy and safety of adalimumab for the Crohn's disease: a systematic review and meta-analysis of published randomized placebo-controlled trialsQ35177220
Ulcerative colitis in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survivalQ35359125
A pooled analysis of infections, malignancy, and mortality in infliximab- and immunomodulator-treated adult patients with inflammatory bowel diseaseQ36078334
Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT™ registryQ36223905
Role of neutrophil-derived oxidants in the pathogenesis of intestinal inflammationQ36465773
A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitisQ36720362
Psoriasis and pustular dermatitis triggered by TNF-{alpha} inhibitors in patients with rheumatologic conditionsQ36740090
Biologics in Crohn's disease: searching indicators for outcomeQ36909385
Direct health care costs of Crohn's disease and ulcerative colitis in US children and adultsQ37035957
Tumor necrosis factor antagonist mechanisms of action: a comprehensive reviewQ37043901
Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial.Q37240622
Comparative effectiveness of infliximab and adalimumab for Crohn's diseaseQ37445629
Anti-TNF-induced lupusQ37471071
Cutaneous side effects of anti-tumor necrosis factor biologic therapy: a clinical reviewQ37560336
Clinical implications of mucosal healing for the management of IBD.Q37641754
A Systematic Review of Factors That Contribute to Hepatosplenic T-Cell Lymphoma in Patients With Inflammatory Bowel DiseaseQ37796190
Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysisQ37853359
Risk stratification for progressive multifocal leukoencephalopathy in patients treated with natalizumabQ37982013
Anti-TNF monoclonal antibodies in inflammatory bowel disease: pharmacokinetics-based dosing paradigmsQ37987352
Impact of antibodies to infliximab on clinical outcomes and serum infliximab levels in patients with inflammatory bowel disease (IBD): a meta-analysisQ38059422
Progressive multifocal leukoencephalopathy in patients with multiple sclerosisQ38089536
Vedolizumab for the treatment of IBD: a selective therapeutic approach targeting pathogenic a4b7 cells.Q38131826
Demyelination and other neurological adverse events after anti-TNF therapyQ38137583
Treat to target: a proposed new paradigm for the management of Crohn's diseaseQ38137614
Pegylation of biological molecules and potential benefits: pharmacological properties of certolizumab pegolQ38200926
Update on anti-tumor necrosis factor agents in Crohn diseaseQ38238708
Converging goals of treatment of inflammatory bowel disease from clinical trials and practiceQ38240237
Long-term safety and efficacy of certolizumab pegol in the treatment of Crohn's disease: 7-year results from the PRECiSE 3 studyQ38425063
Vedolizumab: An integrin-receptor antagonist for treatment of Crohn's disease and ulcerative colitisQ38551323
Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trialQ39742714
Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohortQ40186159
Increased risk for demyelinating diseases in patients with inflammatory bowel disease.Q40391419
Outside-to-inside signal through the membrane TNF-alpha induces E-selectin (CD62E) expression on activated human CD4+ T cellsQ40836468
Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophagesQ40875345
Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative ColitisQ43553836
Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort studyQ43731459
Drug therapies and the risk of malignancy in Crohn's disease: results from the TREAT™ Restaurantmanhaj'sQ43778384
Rising incidence of inflammatory bowel disease among children: a 12-year studyQ44075741
Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trialQ44151825
Crohn's disease in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survivalQ44671543
Association between pharmacokinetics of adalimumab and mucosal healing in patients with inflammatory bowel diseases.Q44702374
Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximabQ44742543
Severe skin lesions cause patients with inflammatory bowel disease to discontinue anti-tumor necrosis factor therapyQ44771716
The incidence and predictors of lupus-like reaction in patients with IBD treated with anti-TNF therapiesQ44803722
Still in pursuitQ45194269
High prevalence of inflammatory bowel disease in United States residents of Indian ancestryQ45326837
Dual therapy with infliximab and immunomodulator reduces one-year rates of hospitalization and surgery among veterans with inflammatory bowel diseaseQ45329439
Length of hospital stay and associated hospital costs with infliximab versus cyclosporine in severe ulcerative colitisQ45734256
Adalimumab-induced autoimmune hepatitis.Q45932142
A histopathologic scoring system as a tool for standardized reporting of chronic (ileo)colitis and independent risk assessment for inflammatory bowel diseaseQ46230892
Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitisQ46286038
Meta-analysis: pre-operative infliximab treatment and short-term post-operative complications in patients with ulcerative colitisQ46400709
Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment: a randomised, controlled trialQ46533213
Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrinQ46549276
Natalizumab for the treatment of active Crohn's disease: results of the ENCORE TrialQ46688826
Ten years of infliximab for Crohn's disease: outcome in 469 patients from 2 tertiary referral centersQ46763092
Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failedQ46835906
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectinflammatory bowel diseasesQ917447
P304page(s)1915-1934
P577publication date2015-11-11
P1433published inExpert Opinion on Drug SafetyQ5421206
P1476titleBalancing the risks and benefits of biologic therapy in inflammatory bowel diseases
P478volume14

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