| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S11095-015-1829-5 |
| P8608 | Fatcat ID | release_77ryn6k3gvhdrdqigeer27lqba |
| P698 | PubMed publication ID | 26597939 |
| P50 | author | Thomas Rades | Q37828574 |
| Ben J. Boyd | Q41608617 | ||
| P2093 | author name string | Jamal Khan | |
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| A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats | Q80235982 | ||
| Pharmaceutical co-crystals-an opportunity for drug product enhancement | Q83614628 | ||
| Real time evolution of liquid crystalline nanostructure during the digestion of formulation lipids using synchrotron small-angle X-ray scattering | Q84376066 | ||
| Study of drug concentration effects on in vitro lipolysis kinetics in medium-chain triglycerides by considering oil viscosity and surface tension | Q84872458 | ||
| In vivo dog intestinal precipitation of mebendazole: a basic BCS class II drug | Q84940584 | ||
| pH-driven colloidal transformations based on the vasoactive drug nicergoline | Q86022181 | ||
| Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation | Q86352456 | ||
| The potential for drug supersaturation during intestinal processing of lipid-based formulations may be enhanced for basic drugs | Q86839995 | ||
| Lipid absorption triggers drug supersaturation at the intestinal unstirred water layer and promotes drug absorption from mixed micelles | Q86993897 | ||
| Toward an improved understanding of the precipitation behavior of weakly basic drugs from oral lipid-based formulations | Q87269856 | ||
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| In Situ Lipolysis and Synchrotron Small-Angle X-ray Scattering for the Direct Determination of the Precipitation and Solid-State Form of a Poorly Water-Soluble Drug During Digestion of a Lipid-Based Formulation | Q38965116 | ||
| Bioavailability of phenytoin in lipid containing dosage forms in rats | Q39197020 | ||
| Effect of precipitation inhibitors on indomethacin supersaturation maintenance: mechanisms and modeling | Q39225919 | ||
| Drug precipitation-permeation interplay: supersaturation in an absorptive environment | Q39306982 | ||
| An in vitro methodology for forecasting luminal concentrations and precipitation of highly permeable lipophilic weak bases in the fasted upper small intestine | Q39569609 | ||
| Advancing in-vitro drug precipitation testing: new process monitoring tools and a kinetic nucleation and growth model | Q39729707 | ||
| Biopharmaceutical challenges associated with drugs with low aqueous solubility--the potential impact of lipid-based formulations. | Q40141200 | ||
| Structural aspects of digestion of medium chain triglycerides studied in real time using sSAXS and Cryo-TEM. | Q41610497 | ||
| Use of the Biopharmaceutical Classification System in early drug development | Q41822381 | ||
| Supersaturated self-nanoemulsifying drug delivery systems (Super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs | Q42507291 | ||
| Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate | Q43006891 | ||
| Evaluation of the structural determinants of polymeric precipitation inhibitors using solvent shift methods and principle component analysis. | Q43782639 | ||
| In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products. | Q43827542 | ||
| USP dissolution IV: comparison of methods | Q43849949 | ||
| Insights into drug precipitation kinetics during in vitro digestion of a lipid-based drug delivery system using in-line raman spectroscopy and mathematical modeling | Q43852623 | ||
| Amorphous compositions using concentration enhancing polymers for improved bioavailability of itraconazole. | Q44037008 | ||
| Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations. | Q44630513 | ||
| Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine | Q44773921 | ||
| Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations | Q44806110 | ||
| Raman mapping for kinetic analysis of crystallization of amorphous drug based on distributional images. | Q44813529 | ||
| Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation. | Q44890935 | ||
| A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs. | Q45068539 | ||
| Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug. | Q45201690 | ||
| Supersaturating drug delivery systems: fast is not necessarily good enough. | Q45220756 | ||
| Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir | Q45397786 | ||
| Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug delivery systems. | Q45899316 | ||
| Lipid-based formulations to enhance oral bioavailability of the poorly water-soluble drug anethol trithione: effects of lipid composition and formulation. | Q45976343 | ||
| Characterization and optimization of AMG 517 supersaturatable self-emulsifying drug delivery system (S-SEDDS) for improved oral absorption | Q46098972 | ||
| Design of lipid-based formulations for oral administration of poorly water-soluble drugs: precipitation of drug after dispersion of formulations in aqueous solution. | Q46171170 | ||
| Drug-excipient complexation in lipid based delivery systems: an investigation of the Tipranavir-1,3-dioctanolyglycerol complex | Q46378498 | ||
| Better understanding of dissolution behaviour of amorphous drugs by in situ solid-state analysis using Raman spectroscopy | Q46509855 | ||
| Bile increases intestinal lymphatic drug transport in the fasted rat. | Q46678360 | ||
| Formation of highly organized nanostructures during the digestion of milk | Q46974949 | ||
| pH-Induced precipitation behavior of weakly basic compounds: determination of extent and duration of supersaturation using potentiometric titration and correlation to solid state properties. | Q51369136 | ||
| Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults. | Q51372033 | ||
| Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen. | Q51542358 | ||
| Upper gastrointestinal (GI) pH in young, healthy men and women. | Q51615125 | ||
| Forms and applications of the nucleation theorem. | Q51936830 | ||
| Assessing the impact of polymers on the pH-induced precipitation behavior of poorly water soluble compounds using synchrotron wide angle X-ray scattering. | Q53624978 | ||
| Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion | Q58199067 | ||
| Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations | Q58199070 | ||
| P433 | issue | 3 | |
| P304 | page(s) | 548-562 | |
| P577 | publication date | 2015-11-23 | |
| P1433 | published in | Pharmaceutical Research | Q7180737 |
| P1476 | title | The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations | |
| P478 | volume | 33 |
| Q42392490 | A Mixed Micelle Formulation for Oral Delivery of Vitamin K |
| Q64097304 | Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion |
| Q38808298 | Application of UV Imaging in Formulation Development |
| Q101216405 | Applying Computational Predictions of Biorelevant Solubility Ratio upon Self-Emulsifying Lipid-Based Formulations Dispersion to Predict Dose Number |
| Q91603964 | Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension |
| Q57129432 | Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations |
| Q38926514 | Lipid-associated oral delivery: Mechanisms and analysis of oral absorption enhancement |
| Q92306249 | Mechanisms of increased bioavailability through amorphous solid dispersions: a review |
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