scholarly article | Q13442814 |
P356 | DOI | 10.3109/08830185.2015.1087519 |
P698 | PubMed publication ID | 26606328 |
P50 | author | Bluyssen H | Q72285833 |
Joanna Wesoły | Q95835476 | ||
P2093 | author name string | Stefan Chmielewski | |
Anna Piaszyk-Borychowska | |||
P2860 | cites work | Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in L-NAME-induced hypertension. | Q43797072 |
Evidence for a role of toll-like receptor 4 in development of chronic allograft rejection after cardiac transplantation | Q45153732 | ||
Pravastatin attenuates interferon-gamma action via modulation of STAT1 to prevent aortic atherosclerosis in apolipoprotein E-knockout mice | Q46238735 | ||
Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome | Q46481417 | ||
Increased CD74 expression in human atherosclerotic plaques: contribution to inflammatory responses in vascular cells | Q47858881 | ||
Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis. | Q50479986 | ||
High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice. | Q50554632 | ||
Modulation of vascular smooth muscle cell phenotype by STAT-1 and STAT-3. | Q51519556 | ||
SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNγ. | Q54367716 | ||
Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. | Q54596085 | ||
In silico simulations of STAT1 and STAT3 inhibitors predict SH2 domain cross-binding specificity. | Q54630289 | ||
Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice | Q57574582 | ||
Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice | Q58149069 | ||
Interferon-γ elicits arteriosclerosis in the absence of leukocytes | Q59064332 | ||
Projections of global mortality and burden of disease from 2002 to 2030 | Q21144688 | ||
Structural bases of unphosphorylated STAT1 association and receptor binding | Q24298555 | ||
ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells | Q24672345 | ||
Atherosclerosis — An Inflammatory Disease | Q26776972 | ||
The influence of innate and adaptive immune responses on atherosclerosis | Q27000370 | ||
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors | Q27860900 | ||
Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome | Q28138857 | ||
Mechanisms of type-I- and type-II-interferon-mediated signalling | Q28247893 | ||
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation | Q28288257 | ||
Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants | Q28290376 | ||
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways | Q28297876 | ||
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes | Q28508859 | ||
Identification of STAT1 and STAT3 specific inhibitors using comparative virtual screening and docking validation | Q28543632 | ||
Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation | Q28576748 | ||
Compensatory dendritic cell development mediated by BATF-IRF interactions | Q28586184 | ||
BATF-JUN is critical for IRF4-mediated transcription in T cells | Q28590152 | ||
Metabolic endotoxemia initiates obesity and insulin resistance | Q29547720 | ||
Stats: transcriptional control and biological impact | Q29547776 | ||
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling | Q29615457 | ||
Toll-like receptors and innate immunity | Q29615458 | ||
Phenotypic modulation of macrophages in response to plaque lipids | Q30413906 | ||
Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. | Q30481584 | ||
Data mining of atherosclerotic plaque transcriptomes predicts STAT1-dependent inflammatory signal integration in vascular disease. | Q30848049 | ||
Inducible nitric oxide synthase deficiency does not affect the susceptibility of mice to atherosclerosis but increases collagen content in lesions | Q32061834 | ||
NO-independent regulatory site on soluble guanylate cyclase | Q32165040 | ||
AP-1 and STAT-1 decoy oligodeoxynucleotides attenuate transplant vasculopathy in rat cardiac allografts | Q33338764 | ||
Therapeutic modulators of STAT signalling for human diseases | Q33684732 | ||
Loss of STAT1 is associated with increased aortic rupture in an experimental model of aortic dissection and aneurysm formation | Q33761769 | ||
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses | Q33819043 | ||
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle | Q33932725 | ||
Immunological and cardiometabolic risk factors in the prediction of type 2 diabetes and coronary events: MONICA/KORA Augsburg case-cohort study | Q33932928 | ||
A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells | Q33935165 | ||
Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E | Q33962949 | ||
Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells | Q33967700 | ||
The immune system in atherosclerosis | Q34164644 | ||
Macrophages in atherosclerosis: a dynamic balance. | Q34368005 | ||
A20 regulates atherogenic interferon (IFN)-γ signaling in vascular cells by modulating basal IFNβ levels. | Q34467421 | ||
Inflammation, immunity, and hypertension | Q34528283 | ||
Role of toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein E-deficient mice | Q34555906 | ||
Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. | Q34629986 | ||
STAT1 signaling is not regulated by a phosphorylation-acetylation switch | Q35096677 | ||
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis | Q35144610 | ||
Comparative screening and validation as a novel tool to identify STAT-specific inhibitors | Q35237252 | ||
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques | Q35250952 | ||
STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic responses in human atherosclerosis | Q35493777 | ||
The interferon in TLR signaling: more than just antiviral | Q35557279 | ||
Role of endothelial dysfunction in atherosclerosis | Q35806066 | ||
Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages. | Q35847894 | ||
Regulation of STAT signaling by acetylation | Q35998100 | ||
The yin and yang of type I interferon activity in bacterial infection | Q36234715 | ||
Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex | Q36351968 | ||
The immune response in atherosclerosis: a double-edged sword | Q36508676 | ||
Signal integration between IFNgamma and TLR signalling pathways in macrophages | Q36571648 | ||
Small-molecule inhibitors of signal transducer and activator of transcription 3 protect against angiotensin II-induced vascular dysfunction and hypertension | Q36660171 | ||
Endotoxemia is related to systemic inflammation and atherosclerosis in peritoneal dialysis patients | Q36666840 | ||
Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation | Q36821740 | ||
STAT1 as a central mediator of IFNγ and TLR4 signal integration in vascular dysfunction | Q36895444 | ||
STAT transcription in the ischemic heart | Q36895468 | ||
Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E | Q36986664 | ||
Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms | Q37071983 | ||
New and recurrent gain-of-function STAT1 mutations in patients with chronic mucocutaneous candidiasis from Eastern and Central Europe. | Q37130222 | ||
Biology and significance of the JAK/STAT signalling pathways | Q37146441 | ||
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity | Q37164859 | ||
A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation | Q37246506 | ||
Inteferons pen the JAK-STAT pathway | Q37259013 | ||
Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene | Q37284465 | ||
The role of adaptive T cell immunity in atherosclerosis | Q37339539 | ||
IFN-gamma potentiates atherosclerosis in ApoE knock-out mice | Q37368296 | ||
Interferon-gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts | Q37370287 | ||
Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture | Q37394705 | ||
Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases | Q37414046 | ||
Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin. | Q37546984 | ||
IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling | Q37594217 | ||
Phosphorylation-acetylation switch in the regulation of STAT1 signaling | Q37625138 | ||
The roles of Toll-like receptors in atherosclerosis. | Q37726729 | ||
Complex links between dietary lipids, endogenous endotoxins and metabolic inflammation. | Q37740254 | ||
The expression and functions of toll-like receptors in atherosclerosis | Q37774869 | ||
The JAK-STAT pathway at twenty | Q38004201 | ||
The HAT/HDAC interplay: multilevel control of STAT signaling | Q38044539 | ||
Recent advances in the role of immunity in atherosclerosis | Q38169131 | ||
Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells | Q38340967 | ||
STATs dimerize in the absence of phosphorylation | Q38353169 | ||
Oncotype DX(®) colon cancer assay for prediction of recurrence risk in patients with stage II and III colon cancer: A review of the evidence | Q38377402 | ||
TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice. | Q39260793 | ||
STAT1-mediated signal integration between IFNγ and LPS leads to increased EC and SMC activation and monocyte adhesion. | Q39586956 | ||
Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development | Q40126964 | ||
Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells | Q40677997 | ||
Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain | Q41073163 | ||
HMEC-1: establishment of an immortalized human microvascular endothelial cell line | Q41592068 | ||
Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia | Q41814200 | ||
Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity | Q41834087 | ||
Interferon regulatory factors in heart: stress response beyond inflammation | Q42637206 | ||
Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice | Q42757050 | ||
CD11c(+) dendritic cells maintain antigen processing, presentation capabilities, and CD4(+) T-cell priming efficacy under hypercholesterolemic conditions associated with atherosclerosis | Q43145952 | ||
Jak/STAT signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells | Q43260469 | ||
Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice. | Q43653260 | ||
P433 | issue | 5 | |
P921 | main subject | inflammation | Q101991 |
cardiovascular disease | Q389735 | ||
P304 | page(s) | 434-454 | |
P577 | publication date | 2015-11-25 | |
P1433 | published in | International Reviews of Immunology | Q6052764 |
P1476 | title | STAT1 and IRF8 in Vascular Inflammation and Cardiovascular Disease: Diagnostic and Therapeutic Potential | |
P478 | volume | 35 |
Q58721602 | CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity |
Q64969424 | Direct Inhibition of IRF-Dependent Transcriptional Regulatory Mechanisms Associated With Disease. |
Q37709209 | Dysregulated expression of microRNAs and mRNAs in pulmonary artery remodeling in ascites syndrome in broiler chickens |
Q57798751 | Genome-wide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide |
Q40420570 | In This Issue: Cellular and Molecular Mechanisms Orchestrating the Innate Immunity During Infectious and Non-infectious Disease |
Q51425290 | Inhibition of IRF8 Negatively Regulates Macrophage Function and Impairs Cutaneous Wound Healing. |
Q46290278 | Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model |
Q92617376 | MiR-499a suppresses LPS-induced human vascular endothelial cell inflammatory response and apoptosis by regulating STAT1 |
Q28804081 | RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation |
Q28075782 | San-Huang-Xie-Xin-Tang Constituents Exert Drug-Drug Interaction of Mutual Reinforcement at Both Pharmacodynamics and Pharmacokinetic Level: A Review |
Search more.