Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

scientific article

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI28549
P932PMC publication ID1716202
P698PubMed publication ID17200718

P50authorNico van RooijenQ62569422
Gwendalyn J. RandolphQ88180808
P2093author name stringSergio A Lira
Frank Tacke
Matthias Mack
Jianhua Liu
Rainer Spanbroek
David Alvarez
Alexandre Garin
Claudia Jakubzick
Andreas J Habenicht
Jaime Llodra
Theodore J Kaplan
P2860cites workDefects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptorQ36380911
Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodesQ36399533
Dynamic imaging of the immune system: progress, pitfalls and promiseQ36518928
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaquesQ37416056
The fractalkine receptor CX3CR1 is a key mediator of atherogenesisQ39745003
The CC chemokine MCP-1 stimulates surface expression of CX3CR1 and enhances the adhesion of monocytes to fractalkine/CX3CL1 via p38 MAPK.Q40271786
Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applicationsQ40701479
Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery diseaseQ43777934
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.Q45025551
Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4.Q46754468
Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosisQ46897070
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.Q47914837
Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice.Q52549466
Mouse model of heterotopic aortic arch transplantationQ56971847
Role of Bone Marrow–Derived CC-Chemokine Receptor 5 in the Development of Atherosclerosis of Low-Density Lipoprotein Receptor Knockout MiceQ58149249
Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10Q61612313
Quantitative immunocytochemical characterization of mononuclear phagocytes. II. Monocytes and tissue macrophagesQ68204087
Differential chemokine receptor expression and function in human monocyte subpopulationsQ73792772
Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient miceQ77231603
Characterization of fractalkine (CX3CL1) and CX3CR1 in human coronary arteries with native atherosclerosis, diabetes mellitus, and transplant vascular diseaseQ78594580
Smooth muscle cells in human atherosclerotic plaques express the fractalkine receptor CX3CR1 and undergo chemotaxis to the CX3C chemokine fractalkine (CX3CL1)Q79214234
Expression and characterization of the chemokine receptors CCR2 and CCR5 in miceQ95721029
Langerhans cells arise from monocytes in vivoQ28294423
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout miceQ28585385
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.Q28590391
Blood monocytes consist of two principal subsets with distinct migratory propertiesQ29614286
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigensQ29615098
Visualizing dendritic cell networks in vivoQ29616233
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertionQ29618089
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearanceQ29620412
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2Q29622852
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endotheliumQ30308237
L-selectin: mechanisms and physiological significance of ectodomain cleavage.Q30437162
CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout miceQ30891436
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repairQ33565774
Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic rootQ33580505
Generation and analysis of mice lacking the chemokine fractalkineQ33941435
The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cellsQ34512207
Chemokine receptor CCR1 disruption in bone marrow cells enhances atherosclerotic lesion development and inflammation in miceQ34572318
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of diseaseQ34772143
Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesisQ34828549
Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humansQ34912596
Monocyte chemoattractant protein-1 (CCL2) in inflammatory disease and adaptive immunity: therapeutic opportunities and controversiesQ35173613
The role of chemokines in atherosclerosis: recent evidence from experimental models and population geneticsQ35689477
Chemokines in the pathogenesis of vascular diseaseQ35932790
Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the peripheryQ36228368
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodiesQ36351071
Fractalkine preferentially mediates arrest and migration of CD16+ monocytesQ36370923
Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissuesQ36376423
The CD16(+) (FcgammaRIII(+)) subset of human monocytes preferentially becomes migratory dendritic cells in a model tissue settingQ36376577
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)185-194
P577publication date2007-01-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMonocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
P478volume117

Reverse relations

cites work (P2860)
Q369415131,25(OH)2 vitamin D suppresses macrophage migration and reverses atherogenic cholesterol metabolism in type 2 diabetic patients
Q3671087611β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis
Q388887012014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.
Q30252768A MicroRNA93-Interferon Regulatory Factor-9-Immunoresponsive Gene-1-Itaconic Acid Pathway Modulates M2-Like Macrophage Polarization to Revascularize Ischemic Muscle
Q52684469A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.
Q55064059A Polecat's View of Patrolling Monocytes.
Q34776498A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation
Q42485407A novel flow cytometry-based assay to study leukocyte-endothelial cell interactions in vitro
Q36771337A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
Q42707351A novel type I IFN-producing cell subset in murine lupus
Q35901388AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-κB Pathway in RAW264.7 Macrophages
Q37153606ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression
Q41789790ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation
Q89876337Aberrant activation of bone marrow Ly6C high monocytes in diabetic mice contributes to impaired glucose tolerance
Q35565755Aberrant regulation of the integrin very late antigen-4 in systemic lupus erythematosus
Q42707203Absence of CCR2 results in an inflammaging environment in young mice with age-independent impairments in muscle regeneration
Q37635019Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization
Q41905308Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages
Q36661058Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.
Q42848637Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance.
Q33862296Adipose tissue macrophages in the development of obesity-induced inflammation, insulin resistance and type 2 diabetes
Q33724394Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity
Q44203361Adoptive cytotoxic T lymphocyte therapy triggers a counter-regulatory immunosuppressive mechanism via recruitment of myeloid-derived suppressor cells.
Q37066948Age-associated vascular inflammation promotes monocytosis during atherogenesis.
Q33611462Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults
Q34791186Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration
Q53657848Aged mice have increased inflammatory monocyte concentration and altered expression of cell-surface functional receptors.
Q50568735Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice.
Q92494933Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis
Q97074426Alterations of CCR2 and CX3CR1 on Three Monocyte Subsets During HIV-1/Treponema pallidum Coinfection
Q50695778Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.
Q24300694An oxidized lipid-peroxisome proliferator-activated receptor gamma-chemokine pathway in the regulation of macrophage-vascular smooth muscle cell adhesion
Q91689575Analysis of interleukin-17 and interleukin-18 levels in animal models of atherosclerosis
Q37093590Angiogenesis in eye disease: immunity gained or immunity lost?
Q43143507Angiogenic monocytes: another colorful blow to endothelial progenitors
Q37572203Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes
Q35903298Animal models of atherosclerosis
Q27012536Anti-atherogenic mechanisms of high density lipoprotein: effects on myeloid cells
Q39635867Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin
Q37045337Antigen presentation by monocytes and monocyte-derived cells
Q37439900Antiretroviral treatment interruptions and risk of non-opportunistic diseases
Q35370268ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice
Q35744441ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium
Q90367399Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation
Q42175264Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells.
Q58574858Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases
Q33624371Arterial and fat tissue inflammation are highly correlated: a prospective 18F-FDG PET/CT study.
Q30424809Arteriolar and venular remodeling are differentially regulated by bone marrow-derived cell-specific CX3CR1 and CCR2 expression
Q40784219Association of hydrogen sulfide with alterations of monocyte chemokine receptors, CCR2 and CX3CR1 in patients with coronary artery disease
Q42238390Associations between surface markers on blood monocytes and carotid atherosclerosis in HIV-positive individuals.
Q57132044Atherosclerosis
Q38217731Atherosclerosis--multiple pathways to lesional macrophages
Q37953777Atherosclerosis: current pathogenesis and therapeutic options
Q51105552Atractylenolide I restores HO-1 expression and inhibits Ox-LDL-induced VSMCs proliferation, migration and inflammatory responses in vitro.
Q35728941Balance of inflammatory pathways and interplay of immune cells in the liver during homeostasis and injury
Q36079808Beyond vascular inflammation--recent advances in understanding atherosclerosis
Q27693877Biomechanical factors and macrophages in plaque stability
Q55640686Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis.
Q41147790Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice
Q41484602Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.
Q45962394CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis.
Q30803044CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammation
Q33533950CCR2 and coronary artery disease: a woscops substudy
Q37249670CCR2 promotes hepatic fibrosis in mice
Q33816303CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells
Q41576199CCR5+T-bet+FoxP3+ Effector CD4 T Cells Drive Atherosclerosis
Q33696840CD11c expression in adipose tissue and blood and its role in diet-induced obesity
Q42629748CD11c/CD18 Signals Very Late Antigen-4 Activation To Initiate Foamy Monocyte Recruitment during the Onset of Hypercholesterolemia
Q35684739CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so
Q92717753CD146 deficiency promotes plaque formation in a mouse model of atherosclerosis by enhancing RANTES secretion and leukocyte recruitment
Q36629448CD40 controls CXCR5-induced recruitment of myeloid-derived suppressor cells to gastric cancer
Q36922514CX3CL1 and CX3CR1 in the GL261 murine model of glioma: CX3CR1 deficiency does not impact tumor growth or infiltration of microglia and lymphocytes
Q34163933CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice
Q33554073CX3CR1 deficiency does not influence trafficking of adipose tissue macrophages in mice with diet-induced obesity
Q36392588CX3CR1 deficiency promotes muscle repair and regeneration by enhancing macrophage ApoE production
Q35692948CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis
Q34627881CX3CR1 signaling on monocytes is dispensable after intracerebral hemorrhage
Q43290133CX3CR1-deficiency is associated with increased severity of disease in experimental autoimmune uveitis
Q34096557CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses
Q37346711CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
Q34501912CXCR6 deficiency attenuates pressure overload-induced monocytes migration and cardiac fibrosis through downregulating TNF-α-dependent MMP9 pathway.
Q37183722CYP450-derived oxylipins mediate inflammatory resolution.
Q37217500Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing
Q36160819Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction
Q35952700Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation.
Q35566342Cellular and 3D optical coherence tomography assessment during the initiation and progression of retinal degeneration in the Ccl2/Cx3cr1-deficient mouse
Q38811208Cellular recruitment in myocardial ischaemia/reperfusion injury.
Q36765892Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis.
Q42688383Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice
Q64262203Chemokine Receptor Redundancy and Specificity Are Context Dependent
Q26863520Chemokine contribution in stem cell engraftment into the infarcted myocardium
Q34672038Chemokine receptor CCR5: from AIDS to atherosclerosis
Q34248596Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis
Q37481304Chemokine receptor antagonists: part 2.
Q58758969Chemokine-Induced Macrophage Polarization in Inflammatory Conditions
Q37345875Chemokine-directed immune cell infiltration in acute and chronic liver disease
Q26801787Chemokines and their receptors in Atherosclerosis
Q27024341Chemokines as effector and target molecules in vascular biology
Q37849900Chemokines as targets for therapy
Q37652971Chemokines in the vascular inflammatory response of atherosclerosis
Q37950973Chemokines: established and novel targets in atherosclerosis
Q36016640Chimeric antigen receptor T cells shape myeloid cell function within the tumor microenvironment through IFN-γ and GM-CSF.
Q26861206Cholesterol efflux pathways regulate myelopoiesis: a potential link to altered macrophage function in atherosclerosis
Q54648069Cholesterol, CCR2, and monocyte phenotypes in atherosclerosis.
Q34903713Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways
Q30389726Circadian Influence on Metabolism and Inflammation in Atherosclerosis
Q90984773Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients
Q37151168Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.
Q38411099Clinical significance of monocyte heterogeneity
Q33608738Comparison of gene expression profiles between human and mouse monocyte subsets
Q92983083Constitutive and stimulated macropinocytosis in macrophages: roles in immunity and in the pathogenesis of atherosclerosis
Q30318502Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis
Q36879234Control of both myeloid cell infiltration and angiogenesis by CCR1 promotes liver cancer metastasis development in mice.
Q38025388Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis.
Q37150841Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype
Q35640438Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets.
Q52691045DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice.
Q91120596DNA methyltransferase 1 and Krüppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis
Q64958310Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic plaques of LDLR deficient mice.
Q97525815Deciphering Macrophage Phenotypes upon Lipid Uptake and Atherosclerosis
Q47132046Defective Protein Catabolism in Atherosclerotic Vascular Inflammation
Q89113492Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis
Q37033745Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice
Q35159004Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication
Q33656103Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile
Q38740877Dendritic Cell Trafficking and Function in Rare Lung Diseases
Q38310937Dendritic Cells and Macrophages: Sentinels in the Kidney
Q37624571Dendritic cells in atherosclerosis
Q33651897Dendritic cells in atherosclerotic disease
Q36490200Depletion of CD11c⁺ cells in the CD11c.DTR model drives expansion of unique CD64⁺ Ly6C⁺ monocytes that are poised to release TNF-α
Q38691116Development and Function of Arterial and Cardiac Macrophages
Q39271567Development and Functional Differentiation of Tissue-Resident Versus Monocyte-Derived Macrophages in Inflammatory Reactions
Q50125858Development of an inflammation imaging tracer, 111In-DOTA-DAPTA, targeting chemokine receptor CCR5 and preliminary evaluation in an ApoE-/- atherosclerosis mouse model.
Q50021708Diabetes-mediated myelopoiesis and the relationship to cardiovascular risk.
Q57468635Different phenotypes of non-classical monocytes associated with systemic inflammation, endothelial alteration and hepatic compromise in patients with dengue
Q52560150Differential Interaction of Platelet-Derived Extracellular Vesicles with Leukocyte Subsets in Human Whole Blood.
Q36414956Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
Q43083885Differential expression of the fractalkine chemokine receptor (CX3CR1) in human monocytes during differentiation
Q28742298Discrete derivative: a data slicing algorithm for exploration of sharing biological networks between rheumatoid arthritis and coronary heart disease
Q36773876Disordered haematopoiesis and athero-thrombosis.
Q36776429Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice
Q41106375Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes
Q27333694Divergent JAM-C Expression Accelerates Monocyte-Derived Cell Exit from Atherosclerotic Plaques
Q21285000Diverse roles of macrophages in atherosclerosis: from inflammatory biology to biomarker discovery
Q55236746Dual Affinity Heparin-Based Hydrogels Achieve Pro-Regenerative Immunomodulation and Microvascular Remodeling.
Q37723178Dual targeting of CCR2 and CCR5: therapeutic potential for immunologic and cardiovascular diseases
Q42134468Dynamic immune cell accumulation during flow-induced atherogenesis in mouse carotid artery: an expanded flow cytometry method
Q41781398Effects of Myeloperoxidase-Induced Oxidation on Antiatherogenic Functions of High-Density Lipoprotein.
Q38903993Effects of dyslipidaemia on monocyte production and function in cardiovascular disease
Q49891102Effects of n-3 fatty acid treatment on monocyte phenotypes in humans with hypertriglyceridemia.
Q35132366Effects of niacin on atherosclerosis and vascular function
Q39800370Efferocytosis as a regulator of macrophage chemokine receptor expression and polarization.
Q35391967Elevated atherosclerosis-related gene expression, monocyte activation and microparticle-release are related to increased lipoprotein-associated oxidative stress in familial hypercholesterolemia
Q90050698Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages
Q26739691Emerging role of chemokine CC motif ligand 4 related mechanisms in diabetes mellitus and cardiovascular disease: friends or foes?
Q37260168Emigration of monocyte-derived cells to lymph nodes during resolution of inflammation and its failure in atherosclerosis
Q89266988Endogenous Protection from Ischemic Brain Injury by Preconditioned Monocytes
Q30853668Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis
Q28744262Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis
Q37846143Epithelial-mesenchymal interactions in biliary diseases
Q38507723Equivalence testing in microarray analysis: similarities in the transcriptome of human atherosclerotic and nonatherosclerotic macrophages.
Q36862946Essential contribution of CCL3 to alkali-induced corneal neovascularization by regulating vascular endothelial growth factor production by macrophages
Q37200899Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progression
Q37078664Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice
Q35985220Expanding role of delta-like 4 mediated notch signaling in cardiovascular and metabolic diseases
Q51772184Expression of C-type lectin, SIGNR3, on subsets of dendritic cells, macrophages, and monocytes
Q35687871Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions
Q37082023Fasting glucose level modulates cell surface expression of CD11b and CD66b in granulocytes and monocytes of patients with type 2 diabetes
Q57169759Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease
Q38860053Foamy monocytes form early and contribute to nascent atherosclerosis in mice with hypercholesterolemia
Q36366267Folate receptor: a macrophage "achilles' heel"?
Q36660105Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis
Q34391705Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1.
Q38179249From proliferation to proliferation: monocyte lineage comes full circle
Q35889058Functional alterations of myeloid cell subsets in hyperlipidaemia: relevance for atherosclerosis
Q33604746Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis
Q47598616Functional diversity of macrophages in vascular biology and disease.
Q38217345Functional genomics of the 9p21.3 locus for atherosclerosis: clarity or confusion?
Q37276351Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia
Q39499494Functional role of intrahepatic monocyte subsets for the progression of liver inflammation and liver fibrosis in vivo
Q36331567Functional role of monocytes and macrophages for the inflammatory response in acute liver injury
Q38715488G protein-coupled receptors as targets for anti-diabetic therapeutics
Q64935464G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis.
Q42577780GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions
Q28287747GPR109A and vascular inflammation
Q37163430Gastrointestinal inflammation: lessons from metabolic modulators
Q27316270Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner
Q37165196Genetic polymorphisms in the CD14 gene are associated with monocyte activation and carotid intima-media thickness in HIV-infected patients on antiretroviral therapy
Q91559781Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
Q38258044Glycosyltransferases, glycosylation and atherosclerosis
Q27330751Graft-infiltrating host dendritic cells play a key role in organ transplant rejection
Q42288906Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis
Q46224865HDL Cholesterol Efflux Capacity in Newly Diagnosed HIV and Effects of Antiretroviral Therapy
Q33868782HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells
Q35949916Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility
Q39939397Hematopoietic stem/progenitor cells directly contribute to arteriosclerotic progression via integrin β2
Q58726638Hemodialysis-related changes in phenotypical features of monocytes
Q49524850Hepatic recruitment of CD11b+Ly6C+ inflammatory monocytes promotes hepatic ischemia/reperfusion injury.
Q62735118Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis
Q36512340Heterogeneity of human macrophages in culture and in atherosclerotic plaques
Q83393584Heterogeneity of human monocytes: an optimized four-color flow cytometry protocol for analysis of monocyte subsets
Q30409523Heterogeneity of lung mononuclear phagocytes during pneumonia: contribution of chemokine receptors
Q37446568Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis
Q36546975High-density lipoprotein inhibits human M1 macrophage polarization through redistribution of caveolin-1.
Q34555169Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer
Q91638984How Monocytes Contribute to Increased Risk of Atherosclerosis in Virologically-Suppressed HIV-Positive Individuals Receiving Combination Antiretroviral Therapy
Q58562247How toll-like receptors reveal monocyte plasticity: the cutting edge of antiinflammatory therapy
Q34318508Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo.
Q90724364Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry
Q36920492Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals.
Q27332432Hydrogen sulfide inhibits the development of atherosclerosis with suppressing CX3CR1 and CX3CL1 expression
Q36951483Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children
Q38066291Hypercholesterolemia links hematopoiesis with atherosclerosis.
Q37711215Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis
Q36140871IL1β induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-κB.
Q37234314Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
Q24649151Identification of splenic reservoir monocytes and their deployment to inflammatory sites
Q38064660Imaging macrophage development and fate in atherosclerosis and myocardial infarction
Q44183906Imaging monocytes with iron oxide nanoparticles targeted towards the monocyte integrin MAC-1 (CD11b/CD18) does not result in improved atherosclerotic plaque detection by in vivo MRI.
Q39636702Imaging of hypoxia in mouse atherosclerotic plaques with (64)Cu-ATSM.
Q30316648Imaging systemic inflammatory networks in ischemic heart disease
Q37325024Immune and inflammatory mechanisms of atherosclerosis (*)
Q64979483Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity.
Q37150605Immune effector mechanisms implicated in atherosclerosis: from mice to humans
Q57132246Immunological aspects of atherosclerosis: Figure 1
Q24595843Immunology. Dispensable but not irrelevant
Q36152926Impact of bariatric surgery on carotid artery inflammation and the metabolic activity in different adipose tissues.
Q84521080Impact of chemokine receptor CX3CR1 in human renal allograft rejection
Q31132267Impact of glutathione peroxidase-1 deficiency on macrophage foam cell formation and proliferation: implications for atherogenesis
Q39982049Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.
Q51345939In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice.
Q30543940In vivo imaging implicates CCR2(+) monocytes as regulators of neutrophil recruitment during arthritis
Q42379000In vivo imaging of lung inflammation with neutrophil-specific 68Ga nano-radiotracer
Q27315813Inactivation of Semicarbazide-Sensitive Amine Oxidase Stabilizes the Established Atherosclerotic Lesions via Inducing the Phenotypic Switch of Smooth Muscle Cells
Q57160461Increased ROS production and DNA damage in monocytes are biomarkers of aging and atherosclerosis
Q37310434Increased atherosclerotic lesions in LDL receptor deficient mice with hematopoietic nuclear receptor Rev-erbα knock- down
Q35696560Increased macrophage migration into adipose tissue in obese mice
Q37351980Induction of autoimmunity by pristane and other naturally occurring hydrocarbons.
Q59329436Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype
Q37255877Inflamed adipose tissue, insulin resistance and vascular injury
Q38077322Inflammation and atherosclerosis: direct versus indirect mechanisms
Q38083555Inflammation and immune system interactions in atherosclerosis
Q33834800Inflammation and its resolution as determinants of acute coronary syndromes
Q36174933Inflammation in atherosclerosis
Q33709505Inflammation in atherosclerosis: from pathophysiology to practice
Q36177467Inflammatory Ly-6C(hi) monocytes play an important role in the development of severe transplant arteriosclerosis in hyperlipidemic recipients
Q42644126Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression
Q52720539Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes.
Q28275259Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications
Q35688241Inflammatory monocyte effector mechanisms
Q26861256Inflammatory monocytes and the pathogenesis of viral encephalitis
Q47289858Inflammatory monocytes mediate control of acute alphavirus infection in mice.
Q29622851Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
Q37207091Inflammatory pathways in liver homeostasis and liver injury
Q38788685Inflammatory processes in cardiovascular disease: a route to targeted therapies
Q89838814Inhibition of JAK2 Suppresses Myelopoiesis and Atherosclerosis in Apoe-/- Mice
Q102142948Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis
Q24634492Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
Q33659705Innate and adaptive immunity in atherosclerosis
Q56961974Innate and adaptive immunity in atherosclerosis
Q34980214Innate immunity and monocyte-macrophage activation in atherosclerosis.
Q55253701Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression.
Q36984213Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice
Q51302492Integrin αMβ2 is differently expressed by subsets of human osteoclast precursors and mediates adhesion of classical monocytes to bone.
Q39150057Interaction of endothelial cells with macrophages-linking molecular and metabolic signaling
Q41874262Interleukin 17 receptor A modulates monocyte subsets and macrophage generation in vivo
Q36379539Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype
Q30421700Interleukin-1β modulates smooth muscle cell phenotype to a distinct inflammatory state relative to PDGF-DD via NF-κB-dependent mechanisms
Q33881232Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency
Q48575325Intermediate and nonclassical monocytes show heterogeneity in patients with different types of acute coronary syndrome.
Q37432097International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors
Q26852026Interplay of NK cells and monocytes in vascular inflammation and myocardial infarction
Q37522003Intestinal macrophages: differentiation and involvement in intestinal immunopathologies.
Q36204857Intimal pericytes as the second line of immune defence in atherosclerosis
Q92049193KLF2 in Myeloid Lineage Cells Regulates the Innate Immune Response during Skeletal Muscle Injury and Regeneration
Q38031130Kruppel-like factors and vascular inflammation: implications for atherosclerosis
Q40645397LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis
Q34360087LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression
Q64112194Lack of IκBNS promotes cholate-containing high-fat diet-induced inflammation and atherogenesis in low-density lipoprotein (LDL) receptor-deficient mice
Q33561481Leukocyte Trafficking in Cardiovascular Disease: Insights from Experimental Models
Q34322056Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
Q36654171Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum".
Q34668164Lifestyle effects on hematopoiesis and atherosclerosis
Q89107293Limited Macrophage Positional Dynamics in Progressing or Regressing Murine Atherosclerotic Plaques-Brief Report
Q53698113Linkage of Infection to Adverse Systemic Complications: Periodontal Disease, Toll-Like Receptors, and Other Pattern Recognition Systems.
Q37556042Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio.
Q35140825Lipids versus glucose in inflammation and the pathogenesis of macrovascular disease in diabetes
Q37156803Listeria monocytogenes: epidemiology, human disease, and mechanisms of brain invasion
Q28071784Live cell imaging to understand monocyte, macrophage, and dendritic cell function in atherosclerosis
Q43219972Liver fibrosis - pathogenesis and novel therapeutic approaches
Q34492178Local effects of human PCSK9 on the atherosclerotic lesion
Q47405015Local production of tenascin-C acts as a trigger for monocyte/macrophage recruitment that provokes cardiac dysfunction
Q37161176Local proliferation dominates lesional macrophage accumulation in atherosclerosis
Q26750473Long-term activation of the innate immune system in atherosclerosis
Q42987834Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis
Q36537611Longitudinal, Diet-induced Weight Gain is Associated with Increased Blood Monocytes and Reduced TLR4 Expression
Q39938314Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages
Q24628806Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependent
Q90131716Lung Transplantation Has a Strong Impact on the Distribution and Phenotype of Monocyte Subsets
Q43511144Ly-6C(hi) monocytes: a potential target for preventing transplant arteriosclerosis?
Q35644935Ly6C- Monocytes Regulate Parasite-Induced Liver Inflammation by Inducing the Differentiation of Pathogenic Ly6C+ Monocytes into Macrophages
Q27486985Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis
Q36979954Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes
Q38776911Lymphatic network in atherosclerosis: the underestimated path.
Q33399367Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice
Q54541923M1 macrophages act as LTβR-independent lymphoid tissue inducer cells during atherosclerosis-related lymphoid neogenesis.
Q64120737M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment
Q40414424MARCH1 E3 Ubiquitin Ligase Dampens the Innate Inflammatory Response by Modulating Monocyte Functions in Mice.
Q26800135MIF and CXCL12 in Cardiovascular Diseases: Functional Differences and Similarities
Q57185167MRI of inducible P-selectin expression in human activated platelets involved in the early stages of atherosclerosis
Q51736533MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Q36602809Macrophage Phenotype and Function in Different Stages of Atherosclerosis
Q58592678Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)
Q36584242Macrophage autophagy in atherosclerosis
Q36196806Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
Q38008842Macrophage differentiation and function in atherosclerosis: opportunities for therapeutic intervention?
Q36955562Macrophage diversity in renal injury and repair.
Q38893448Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases
Q42023507Macrophage heterogeneity and tissue lipids
Q37594434Macrophage heterogeneity in atherosclerotic plaques
Q26861223Macrophage heterogeneity in tissues: phenotypic diversity and functions
Q39867198Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species
Q42223802Macrophage migration inhibitory factor and CD74 regulate macrophage chemotactic responses via MAPK and Rho GTPase.
Q37624935Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-κB-mediated inflammation in macrophages.
Q38554081Macrophage polarization in pathology
Q37990243Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine
Q89463384Macrophage subsets in atherosclerosis as defined by single-cell technologies
Q40558304Macrophage/monocyte-specific deletion of Ras homolog gene family member A (RhoA) downregulates fractalkine receptor and inhibits chronic rejection of mouse cardiac allografts.
Q63915886Macrophages and Cardiovascular Health
Q39271676Macrophages and RhoA Pathway in Transplanted Organs.
Q38462573Macrophages and immune cells in atherosclerosis: recent advances and novel concepts
Q49026058Macrophages and lipid metabolism.
Q37294955Macrophages heterogeneity in atherosclerosis - implications for therapy.
Q34368005Macrophages in atherosclerosis: a dynamic balance.
Q30525251Macrophages in collateral arteriogenesis.
Q38965333Macrophages in neuroinflammation: role of the renin-angiotensin-system.
Q29617765Macrophages in the pathogenesis of atherosclerosis
Q39123553Macrophages in vascular inflammation and atherosclerosis
Q26825052Macrophages in vascular inflammation--From atherosclerosis to vasculitis
Q30432565Macrophages, dendritic cells, and kidney ischemia-reperfusion injury
Q64106073Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation
Q36218472Making a difference: monocyte heterogeneity in cardiovascular disease
Q37154824Matrine Inhibits Infiltration of the Inflammatory Gr1(hi) Monocyte Subset in Injured Mouse Liver through Inhibition of Monocyte Chemoattractant Protein-1
Q37272221Mechanisms and consequences of dendritic cell migration
Q37097322Mechanisms of failed apoptotic cell clearance by phagocyte subsets in cardiovascular disease
Q39294420Mechanisms of hepatic stellate cell activation
Q37096570Mechanisms of leukocyte migration across the blood-retina barrier
Q33761114Mechanisms that regulate macrophage burden in atherosclerosis
Q49190975Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E-/- Mice.
Q85945994Mesenchymal stem cells alleviate atherosclerosis by elevating number and function of CD4(+)CD25 (+)FOXP3 (+) regulatory T-cells and inhibiting macrophage foam cell formation
Q60961590Metabolism Plays a Key Role during Macrophage Activation
Q38771095Metalloproteinase production from macrophages - a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction
Q63560419Methods to Study Monocyte and Macrophage Trafficking in Atherosclerosis Progression and Resolution
Q55514960MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways.
Q36519806MicroRNA-33 deficiency reduces the progression of atherosclerotic plaque in ApoE-/- mice
Q57170593MicroRNAs and immunity in periodontal health and disease
Q37623996Microdomains, Inflammation, and Atherosclerosis.
Q35269888Microparticles from apoptotic platelets promote resident macrophage differentiation.
Q28083768Minireview: Emerging Concepts in Islet Macrophage Biology in Type 2 Diabetes
Q41824538Mobilization and margination of bone marrow Gr-1high monocytes during subclinical endotoxemia predisposes the lungs toward acute injury
Q47196473Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice.
Q35591762Modulation of recombinant antigenic constructs containing multi-epitopes towards effective reduction of atherosclerotic lesion in B6;129S-Ldlr(tm1Her)Apob(tm2Sgy)/J mice
Q64913160Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis.
Q87439859Molecular mechanisms regulating CD13-mediated adhesion
Q37992524Molecular pathways regulating macrophage polarization: implications for atherosclerosis
Q40959246Monocyte Adhesion and Plaque Recruitment During Atherosclerosis Development Is Regulated by the Adapter Protein Chat-H/SHEP1
Q92188890Monocyte Based Correlates of Immune Activation and Viremia in HIV-Infected Long-Term Non-Progressors
Q47598516Monocyte Recruitment Versus Macrophage Proliferation in Atherosclerosis
Q47854446Monocyte Subsets Are Differentially Lost from the Circulation during Acute Inflammation Induced by Human Experimental Endotoxemia.
Q37890185Monocyte and macrophage dynamics during atherogenesis
Q37122225Monocyte and macrophage heterogeneity in the heart
Q26991973Monocyte heterogeneity in cardiovascular disease
Q43143047Monocyte mayhem: do subtypes modulate distinct atherosclerosis phenotypes?
Q29620067Monocyte recruitment during infection and inflammation
Q37992796Monocyte subpopulations and cardiovascular risk in chronic kidney disease
Q33450605Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors
Q50065330Monocyte subsets and their phenotypes during treatment with BCR-ABL1 tyrosine kinase inhibitors for Philadelphia chromosome-positive leukemia.
Q35230750Monocyte trafficking in acute and chronic inflammation
Q34065838Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression
Q47632654Monocyte-Macrophages and T Cells in Atherosclerosis
Q37116502Monocyte-endothelial cell interactions in the development of atherosclerosis
Q38791792Monocyte-mediated defense against bacteria, fungi, and parasites
Q34065898Monocyte-mediated defense against microbial pathogens.
Q38079293Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration
Q89967822Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes
Q33949943Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease.
Q37028772Monocytes and macrophages in cancer: development and functions
Q36981636Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design
Q22251045Monocytes in atherosclerosis: subsets and functions
Q38199685Monocytes in health and disease - Minireview
Q34959012Monocytes in sterile inflammation: recruitment and functional consequences
Q28390589Monocytes link atherosclerosis and cancer
Q89929009Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism
Q64966156Monocytes, Macrophages, and Metabolic Disease in Atherosclerosis.
Q33942337Monocytes: protagonists of infarct inflammation and repair after myocardial infarction
Q38063587Mononuclear phagocyte system in kidney disease and repair.
Q39250977MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4.
Q33392688MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.
Q36043804Mycophenolate mofetil decreases atherosclerotic lesion size by depression of aortic T-lymphocyte and interleukin-17-mediated macrophage accumulation
Q43894319Myeloid Bmal1 deletion increases monocyte recruitment and worsens atherosclerosis.
Q36930766Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice
Q88985831Myeloid cell contributions to cardiovascular health and disease
Q34076117Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice
Q38134246Myeloid cells in atherosclerosis: a delicate balance of anti-inflammatory and proinflammatory mechanisms
Q37399947Myeloid cells in atherosclerosis: initiators and decision shapers
Q37242355Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
Q33968125Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice
Q35589891Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Q36106602Myocardial infarction accelerates atherosclerosis.
Q42573987NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis
Q39417189NR4A1-dependent Ly6Clow monocytes contribute to reducing joint inflammation in arthritic mice through Treg cells
Q38537648Nanoparticle uptake by macrophages in vulnerable plaques for atherosclerosis diagnosis
Q100455083Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
Q57817810Nature and nurture of tissue-specific macrophage phenotypes
Q27329117Nestin(+) cells direct inflammatory cell migration in atherosclerosis.
Q92714930Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity
Q37695058Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Q36104871Neutrophil secretion products pave the way for inflammatory monocytes
Q36984720Neutrophil-derived cathelicidin promotes adhesion of classical monocytes
Q42433273Neutrophils in atherosclerosis: alarmin evidence of a hit and run?
Q49531175New Insights into the Immunobiology of Mononuclear Phagocytic Cells and Their Relevance to the Pathogenesis of Cardiovascular Diseases.
Q36084389Niacin in cardiovascular disease: recent preclinical and clinical developments
Q35608570Niacin inhibits skin dendritic cell mobilization in a GPR109A independent manner but has no impact on monocyte trafficking in atherosclerosis
Q37476547Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling
Q30252830Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury.
Q28080570Nonclassical patrolling monocyte function in the vasculature
Q37328829Noninvasive MRI monitoring of the effect of interventions on endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent
Q36079508Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders
Q38032155Novel immune signals and atherosclerosis
Q37462172Obesity, inflammation, and atherosclerosis
Q36200739Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions
Q37571905Omega-3 fatty acids: mechanisms underlying 'protective effects' in atherosclerosis
Q37117925On-chip phenotypic analysis of inflammatory monocytes in atherogenesis and myocardial infarction
Q38763465Ontogeny of Tumor-associated Macrophages and Its Implication in Cancer Regulation
Q36750759Organ-specific features of natural killer cells
Q45159606Origin of monocytes and macrophages in a committed progenitor
Q59806954Origin, Differentiation, and Function of Intestinal Macrophages
Q40780259Orthodontic Force Induces Systemic Inflammatory Monocyte Responses
Q41166170P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice
Q37612342P-selectin glycoprotein ligand-1 plays a crucial role in the selective recruitment of leukocytes into the atherosclerotic arterial wall.
Q42101139P2Y₆ receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells
Q37383780PET/CT Imaging of Chemokine Receptors in Inflammatory Atherosclerosis Using Targeted Nanoparticles
Q34632459PET/CT imaging of chemokine receptor CCR5 in vascular injury model using targeted nanoparticle
Q37790384PPARs as therapeutic targets in cardiovascular disease
Q47193091Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation
Q37258449Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus
Q37760424Phagocyte partnership during the onset and resolution of inflammation.
Q91281532Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice
Q87203689Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C(+) macrophage infiltration in mice
Q30413906Phenotypic modulation of macrophages in response to plaque lipids
Q40675523Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy
Q36064574Plasmacytoid dendritic cells in atherosclerosis
Q37705023Platelet-derived chemokines: pathophysiology and therapeutic aspects
Q37869351Porphyromonas gingivalis-dendritic cell interactions: consequences for coronary artery disease
Q38646650Primed Polymorphonuclear Leukocytes (PMNLs) from Hemodialysis Patients Enhance Monocyte Transendothelial Migration
Q37639995Proatherogenic conditions promote autoimmune T helper 17 cell responses in vivo
Q29619982Progress and challenges in translating the biology of atherosclerosis
Q37108304Progression and disruption of advanced atherosclerotic plaques in murine models
Q42004933Proliferating macrophages populate established atherosclerotic lesions.
Q46617138Proliferating macrophages prevail in atherosclerosis
Q36862833Properties of human blood monocytes. II. Monocytes from healthy adults are highly heterogeneous within and among individuals
Q47098170Proportions of Proinflammatory Monocytes Are Important Predictors of Mortality Risk in Hemodialysis Patients.
Q41894347Prostaglandin E 2 Does Not Modulate CCR7 Expression and Functionality after Differentiation of Blood Monocytes into Macrophages
Q38991262Protective and pathogenic roles of CD8(+) T cells in atherosclerosis
Q47989935Protective role for CCR5 in murine lupus nephritis
Q38854845Protein Thiol Redox Signaling in Monocytes and Macrophages
Q27319442Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy
Q35218126RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling
Q36055706RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality
Q35171696Raised soluble P-selectin moderately accelerates atherosclerotic plaque progression
Q30300194Recent insights into the cellular biology of atherosclerosis
Q36449773Redefining Myeloid Cell Subsets in Murine Spleen
Q30525793Redox regulation of MAPK phosphatase 1 controls monocyte migration and macrophage recruitment
Q34625670Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling
Q38560870Regression of Atherosclerosis: The Journey From the Liver to the Plaque and Back
Q24631052Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses
Q34372534Regulation and consequences of monocytosis
Q26852339Regulation of an inflammatory disease: Krüppel-like factors and atherosclerosis
Q27003124Regulation of atherogenesis by chemokines and chemokine receptors
Q38396097Regulation of atherosclerotic plaque inflammation
Q28537905Regulation of diet-induced adipose tissue and systemic inflammation by salicylates and pioglitazone
Q27022667Regulation of macrophage and dendritic cell responses by their lineage precursors
Q35906690Regulation of monocyte functional heterogeneity by miR-146a and Relb
Q58148836Regulation of monocyte subset systemic levels by distinct chemokine receptors controls post-ischaemic neovascularization
Q37435783Regulation of the migration and survival of monocyte subsets by chemokine receptors and its relevance to atherosclerosis
Q26825806Repair after myocardial infarction, between fantasy and reality: the role of chemokines
Q90750489Replacing Saturated Fat With Unsaturated Fat in Western Diet Reduces Foamy Monocytes and Atherosclerosis in Male Ldlr-/- Mice
Q36775202Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors
Q42789505Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques
Q48888577Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2.
Q36138041Role of Inflammatory Monocytes in Vaccine-Induced Reduction of Helicobacter felis Infection
Q64937621Role of Macrophages in Cardioprotection.
Q50119083Role of Monocytes in Heart Failure and Atrial Fibrillation.
Q92613057Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity
Q92724115Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases
Q37493351Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Q37329566Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system
Q37704741Roles of the chemokine system in development of obesity, insulin resistance, and cardiovascular disease
Q27024450S100A8 and S100A9 in cardiovascular biology and disease
Q34965254SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction
Q38647432STAT1 and IRF8 in Vascular Inflammation and Cardiovascular Disease: Diagnostic and Therapeutic Potential.
Q90440175STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma
Q41932483Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis
Q38577701Selective Dependence of Kidney Dendritic Cells on CX3CR1--Implications for Glomerulonephritis Therapy
Q33742156Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice
Q50041053Selective recruitment of non-classical monocytes promotes skeletal muscle repair.
Q42520959Sequential staining improves detection of CCR2 and CX3CR1 on monocytes when simultaneously evaluating CCR5 by multicolor flow cytometry
Q36168719Serum Amyloid A Facilitates Early Lesion Development in Ldlr-/- Mice
Q58111873Shape Effects of Peptide Amphiphile Micelles for Targeting Monocytes
Q45740766Silencing CX3CR1 production modulates the interaction between dendritic and endothelial cells
Q63560426Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression
Q50308557Skeletal muscle inflammation and insulin resistance in obesity.
Q89013999Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome
Q83396655Soluble form of the endothelial adhesion molecule CD146 binds preferentially CD16+ monocytes
Q27309244Specific depletion of Ly6C(hi) inflammatory monocytes prevents immunopathology in experimental cerebral malaria
Q35167972Stage-specific remodeling of atherosclerotic lesions upon cholesterol lowering in LDL receptor knockout mice
Q28741815Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages
Q34876397Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression
Q92777021Synthesis, 3 H-labelling and in vitro evaluation of a substituted dipiperidine alcohol as a potential ligand for chemokine receptor 2
Q36509966Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity
Q36944695T Cell CX3CR1 Mediates Excess Atherosclerotic Inflammation in Renal Impairment
Q35894071TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity.
Q34787176TNF-alpha-dependent regulation of acute pancreatitis severity by Ly-6C(hi) monocytes in mice
Q37366497TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis.
Q91942438TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse
Q37476718Targeting Innate Immunity for CV Benefit
Q38207732Targeting monocyte and macrophage subpopulations for immunotherapy: a patent review (2009 - 2013).
Q49215161The Aging Risk and Atherosclerosis: A Fresh Look at Arterial Homeostasis.
Q52885440The Anti-Atherosclerotic Effect of Naringin Is Associated with Reduced Expressions of Cell Adhesion Molecules and Chemokines through NF-κB Pathway.
Q36320011The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice
Q49874464The CD300e molecule in mice is an immune-activating receptor.
Q91586251The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
Q35915712The IL-17A/IL-17RA axis plays a proatherogenic role via the regulation of aortic myeloid cell recruitment
Q88399458The Ins and Outs of Myeloid Cells in Atherosclerosis
Q55207637The Pharmacological Targets and Clinical Evidence of Natural Products With Anti-hepatic Inflammatory Properties.
Q26852646The Role of Different Monocyte Subsets in the Pathogenesis of Atherosclerosis and Acute Coronary Syndromes
Q64077128The Role of Monocytes and Macrophages in Human Atherosclerosis, Plaque Neoangiogenesis, and Atherothrombosis
Q64084413The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis
Q33838927The Therapeutic Potential of Anti-Inflammatory Exerkines in the Treatment of Atherosclerosis
Q38424659The chemokine CX3CL1 promotes trafficking of dendritic cells through inflamed lymphatics
Q30439547The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia-reperfusion injury
Q38097660The complexity of arterial classical monocyte recruitment.
Q91386670The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation
Q38195893The dynamic lives of macrophage and dendritic cell subsets in atherosclerosis
Q37774869The expression and functions of toll-like receptors in atherosclerosis
Q37561404The fate of monocytes in atherosclerosis
Q42840907The fractalkine receptor CX₃CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes
Q37029711The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
Q29615381The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
Q88873056The heparan sulfate proteoglycan grip on hyperlipidemia and atherosclerosis
Q33817936The journey from stem cell to macrophage
Q34898069The macrophage: the intersection between HIV infection and atherosclerosis.
Q37505820The monocyte to macrophage transition in the murine sterile wound
Q37282249The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models
Q37741022The multiple roles of monocyte subsets in steady state and inflammation
Q35685440The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques
Q59339809The physiology of foamy phagocytes in multiple sclerosis
Q38236315The plasticity of inflammatory monocyte responses to the inflamed central nervous system.
Q37939625The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis.
Q37350270The role of monocyte phenotype switching in peri-procedural myocardial injury and its involvement in statin therapy
Q37766875The role of monocytes in atherosclerotic coronary artery disease.
Q48175299The role of monocytosis and neutrophilia in atherosclerosis
Q39211384The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases
Q37890186The spatial and developmental relationships in the macrophage family
Q33615950The temporal dynamics of plasma fractalkine levels in ischemic stroke: association with clinical severity and outcome
Q36990612The trafficking of natural killer cells
Q35883418The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes
Q36677300The vessel wall and its interactions
Q28305924Therapeutic inflammatory monocyte modulation using immune-modifying microparticles
Q37684793Therapeutic targeting of chemokine interactions in atherosclerosis
Q50247794Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood.
Q39988367Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration
Q33660251Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling
Q37611168Tracking Monocyte Recruitment and Macrophage Accumulation in Atherosclerotic Plaque Progression Using a Novel hCD68GFP/ApoE-/- Reporter Mouse-Brief Report
Q38422828Transcriptional programming of human macrophages: on the way to systems immunology
Q37700335Transcriptional regulation of beta2-microglobulin demonstrated via a novel genomic and proteomic analysis of percutaneously collected peripheral atheroma
Q57784167Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models
Q35241188Transcriptome analysis in patients with chronic kidney disease on hemodialysis disclosing a key role for CD16+CX3CR1+ monocytes
Q37089723Translating molecular discoveries into new therapies for atherosclerosis
Q37810915Treating atherosclerosis: the potential of Toll-like receptors as therapeutic targets
Q36497238Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs.
Q36111469Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes
Q34076041Tumor progression locus 2 (Tpl2) kinase promotes chemokine receptor expression and macrophage migration during acute inflammation
Q36883079Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.
Q34155021Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites
Q37413679Type I interferon modulates monocyte recruitment and maturation in chronic inflammation
Q30826655Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment
Q92332751Unique primed status of microglia under the systemic autoimmune condition of lupus-prone mice
Q90541775Variety matters: Diverse functions of monocyte subtypes in vascular inflammation and atherogenesis
Q92314078Vascular Macrophages in Atherosclerosis
Q41839703Vascular calcification: harder than it looks
Q30319434Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms
Q42801094Vascular dendritic cells as gatekeepers of lipid accumulation within nascent atherosclerotic plaques
Q33813607Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers
Q52641915Visualization of Monocytic Cells in Regressing Atherosclerotic Plaques by Intravital 2-Photon and Positron Emission Tomography-Based Imaging-Brief Report.
Q36385767Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients
Q37170464Why targeting HDL should work as a therapeutic tool, but has not.
Q37764736Xanthogranulomatous pyelonephritis: critical analysis of 30 patients.
Q34324735miR33 inhibition overcomes deleterious effects of diabetes mellitus on atherosclerosis plaque regression in mice.
Q43172902wRAPping up early monocyte and neutrophil recruitment in atherogenesis via Annexin A1/FPR2 signaling

Search more.