| scholarly article | Q13442814 |
| P50 | author | Christie M. Ballantyne | Q98665268 |
| P2093 | author name string | Huaizhu Wu | |
| P2860 | cites work | Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101) | Q24303870 |
| Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance | Q24617743 | ||
| Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance | Q24629603 | ||
| The protein kinase IKKepsilon regulates energy balance in obese mice | Q24658201 | ||
| Implication of inflammatory signaling pathways in obesity-induced insulin resistance | Q27500365 | ||
| Inflammation and metabolic disorders | Q27860923 | ||
| Obesity is associated with macrophage accumulation in adipose tissue | Q27860976 | ||
| Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance | Q28167026 | ||
| Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta | Q28188643 | ||
| SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 | Q28201656 | ||
| JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity | Q28256254 | ||
| Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity | Q28274712 | ||
| Prevention of fat-induced insulin resistance by salicylate | Q28345600 | ||
| Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis | Q28511505 | ||
| Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase | Q28564620 | ||
| The expression of TNF alpha by human muscle. Relationship to insulin resistance | Q37352139 | ||
| Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. | Q37400702 | ||
| Contribution of the serine kinase c-Jun N-terminal kinase (JNK) to oxidant-induced insulin resistance in isolated rat skeletal muscle | Q37606197 | ||
| Skeletal muscle insulin resistance is the primary defect in type 2 diabetes | Q37624257 | ||
| The cellular and signaling networks linking the immune system and metabolism in disease | Q37991199 | ||
| Inflammation and lipid signaling in the etiology of insulin resistance | Q38007632 | ||
| The role of the renin-angiotensin system in the development of insulin resistance in skeletal muscle | Q38008070 | ||
| Are hypertriglyceridemia and low HDL causal factors in the development of insulin resistance? | Q38188133 | ||
| Myokines in insulin resistance and type 2 diabetes. | Q38199992 | ||
| Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. | Q54529003 | ||
| Signaling Specificity of Interleukin-6 Action on Glucose and Lipid Metabolism in Skeletal Muscle | Q61908396 | ||
| ICAM-1 expression in adipose tissue: effects of diet-induced obesity in mice | Q62710719 | ||
| Activation of human peripheral monocytes by angiotensin II | Q71634273 | ||
| Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat | Q72989982 | ||
| Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus | Q73580467 | ||
| Angiotensin II induces vascular cell adhesion molecule-1 expression in rat vasculature: A potential link between the renin-angiotensin system and atherosclerosis | Q78253256 | ||
| T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity | Q79765934 | ||
| Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes | Q79785476 | ||
| Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways | Q82705613 | ||
| Angiotensin II: a hormone that affects lipid metabolism in adipose tissue | Q83350934 | ||
| Angiotensin-converting enzyme inhibition reverses diet-induced obesity, insulin resistance and inflammation in C57BL/6J mice | Q84069787 | ||
| Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans | Q85754011 | ||
| Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects | Q36906306 | ||
| Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes. | Q36972844 | ||
| High sugar intake and development of skeletal muscle insulin resistance and inflammation in mice: a protective role for PPAR- δ agonism | Q36990467 | ||
| Increased secretion and expression of myostatin in skeletal muscle from extremely obese women. | Q37023094 | ||
| Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice | Q37031087 | ||
| Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species | Q37038026 | ||
| Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes. | Q37065529 | ||
| Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals | Q37072370 | ||
| Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women | Q37161799 | ||
| Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action. | Q37216733 | ||
| Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance | Q37224431 | ||
| Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia | Q37276351 | ||
| JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation | Q37330051 | ||
| Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner | Q28578147 | ||
| Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms | Q28586863 | ||
| A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis | Q28588558 | ||
| Palmitate-activated macrophages confer insulin resistance to muscle cells by a mechanism involving protein kinase C θ and ε | Q28743444 | ||
| Macrophage plasticity and polarization: in vivo veritas | Q29547620 | ||
| Obesity induces a phenotypic switch in adipose tissue macrophage polarization | Q29547686 | ||
| IKK-beta links inflammation to obesity-induced insulin resistance | Q29614285 | ||
| Macrophages, inflammation, and insulin resistance | Q29614351 | ||
| The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance | Q29616026 | ||
| TLR4 links innate immunity and fatty acid-induced insulin resistance | Q29617577 | ||
| A central role for JNK in obesity and insulin resistance | Q29619778 | ||
| Mechanisms for insulin resistance: common threads and missing links | Q29620447 | ||
| Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance | Q33558164 | ||
| Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling | Q33568954 | ||
| CD11c expression in adipose tissue and blood and its role in diet-induced obesity | Q33696840 | ||
| Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue | Q33766991 | ||
| FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases | Q33851027 | ||
| Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans | Q33854029 | ||
| Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes | Q33918445 | ||
| Overexpressing human lipoprotein lipase in mouse skeletal muscle is associated with insulin resistance | Q33945264 | ||
| Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance | Q34105654 | ||
| Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice | Q34178121 | ||
| Intensive lifestyle intervention or metformin on inflammation and coagulation in participants with impaired glucose tolerance | Q34225645 | ||
| Skeletal muscle triglyceride. An aspect of regional adiposity and insulin resistance | Q34248434 | ||
| Muscles, exercise and obesity: skeletal muscle as a secretory organ | Q34265667 | ||
| cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance | Q34285542 | ||
| An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice | Q34327061 | ||
| Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans | Q34388266 | ||
| Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans | Q34403054 | ||
| Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice | Q34562825 | ||
| Critical role of the transient activation of p38 MAPK in the etiology of skeletal muscle insulin resistance induced by low-level in vitro oxidant stress | Q34590505 | ||
| Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus | Q34856870 | ||
| Lipoprotein lipase: from gene to obesity | Q34968373 | ||
| Inflammatory links between obesity and metabolic disease | Q35015802 | ||
| Macrophage deletion of SOCS1 increases sensitivity to LPS and palmitic acid and results in systemic inflammation and hepatic insulin resistance. | Q35123484 | ||
| Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance | Q35227203 | ||
| Macrophages, immunity, and metabolic disease | Q38230879 | ||
| Obesity and cardiovascular disease: role of adipose tissue, inflammation, and the renin-angiotensin-aldosterone system | Q38273163 | ||
| A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways | Q38297619 | ||
| Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to reduced mobility and overweight in mice | Q38351484 | ||
| Renin-angiotensin system: an old player with novel functions in skeletal muscle | Q38375202 | ||
| Regulation of metabolism by the innate immune system | Q38629225 | ||
| Crosstalk between adipokines and myokines in fat browning | Q38797210 | ||
| PLIN2 inhibits insulin-induced glucose uptake in myoblasts through the activation of the NLRP3 inflammasome | Q38853897 | ||
| Foamy monocytes form early and contribute to nascent atherosclerosis in mice with hypercholesterolemia | Q38860053 | ||
| Characterization of the metabolic effects of irisin on skeletal muscle in vitro | Q39029293 | ||
| MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2. | Q39108850 | ||
| Treatment with IFN-gamma prevents insulin-dependent PKB, p70S6k phosphorylation and protein synthesis in mouse C2C12 myogenic cells. | Q39769334 | ||
| PKC-theta knockout mice are protected from fat-induced insulin resistance | Q39989111 | ||
| Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance | Q40177903 | ||
| Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase | Q40227253 | ||
| Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation | Q40362277 | ||
| IKKbeta/NF-kappaB activation causes severe muscle wasting in mice | Q40505119 | ||
| Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages | Q40657188 | ||
| Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex. | Q40701074 | ||
| TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells | Q40954084 | ||
| Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity | Q41834087 | ||
| Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation | Q41838863 | ||
| Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects. | Q42200706 | ||
| Associations of calf inter- and intra-muscular adipose tissue with cardiometabolic health and physical function in community-dwelling older adults | Q42246780 | ||
| ApoE and the role of very low density lipoproteins in adipose tissue inflammation | Q42261977 | ||
| Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle | Q42481769 | ||
| Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance | Q42825169 | ||
| IL-6 selectively stimulates fat metabolism in human skeletal muscle | Q42914691 | ||
| Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. | Q42924282 | ||
| JNK deficiency enhances fatty acid utilization and diverts glucose from oxidation to glycogen storage in cultured myotubes | Q43186387 | ||
| Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues | Q43224134 | ||
| Increased protein kinase C theta in skeletal muscle of diabetic patients | Q43586617 | ||
| Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation | Q43699235 | ||
| Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha | Q44043178 | ||
| Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo | Q44816750 | ||
| Inflammation and nitric oxide production in skeletal muscle of type 2 diabetic patients. | Q44916891 | ||
| Angiotensin II-induced effects on adipose and skeletal muscle tissue blood flow and lipolysis in normal-weight and obese subjects | Q44924291 | ||
| Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients | Q45032343 | ||
| Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice. | Q45877031 | ||
| Postprandial interleukin-6 release from skeletal muscle in men with impaired glucose tolerance can be reduced by weight loss | Q46609219 | ||
| Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone | Q46620643 | ||
| Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. | Q46849818 | ||
| Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle | Q46865480 | ||
| Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes. | Q48962187 | ||
| Energy-restricted high-fat diets only partially improve markers of systemic and adipose tissue inflammation. | Q51391047 | ||
| Diet induction of monocyte chemoattractant protein-1 and its impact on obesity. | Q52566078 | ||
| Effects of Changes in Regional Body Composition on Physical Function in Older Adults: A Pilot Randomized Controlled Trial. | Q53813051 | ||
| The contribution of skeletal muscle tumor necrosis factor-alpha to insulin resistance and hypertension in fructose-fed rats. | Q54029725 | ||
| Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques | Q35250952 | ||
| Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinase | Q35405108 | ||
| LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes | Q35600641 | ||
| Increased macrophage migration into adipose tissue in obese mice | Q35696560 | ||
| Overproduction of angiotensinogen from adipose tissue induces adipose inflammation, glucose intolerance, and insulin resistance | Q35736381 | ||
| IL-15 concentrations in skeletal muscle and subcutaneous adipose tissue in lean and obese humans: local effects of IL-15 on adipose tissue lipolysis | Q35749417 | ||
| Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice | Q35782183 | ||
| Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones | Q35794061 | ||
| The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome | Q35901803 | ||
| The effect of exercise on expression of myokine and angiogenesis mRNA in skeletal muscle of high fat diet induced obese rat. | Q35913175 | ||
| Knockout of STAT3 in skeletal muscle does not prevent high-fat diet-induced insulin resistance | Q35929484 | ||
| CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status | Q36047622 | ||
| Macrophage-mediated inflammation in metabolic disease | Q36060408 | ||
| Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 Diabetes | Q36084420 | ||
| Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism | Q36311581 | ||
| Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Ph | Q36354637 | ||
| Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase | Q36377312 | ||
| ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity | Q36392875 | ||
| Large adipocytes function as antigen-presenting cells to activate CD4(+) T cells via upregulating MHCII in obesity | Q36488875 | ||
| Muscle-specific inflammation induced by MCP-1 overexpression does not affect whole-body insulin sensitivity in mice | Q36547647 | ||
| The renin angiotensin aldosterone system and insulin resistance in humans | Q36550987 | ||
| Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes | Q36560528 | ||
| Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects | Q36580093 | ||
| Inflammation versus host defense in obesity | Q36585287 | ||
| Angiotensin II and inflammation: the effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade | Q36649671 | ||
| Interleukin-6 in acute exercise and training: what is the biological relevance? | Q36698351 | ||
| Angiotensin 1-7 as means to prevent the metabolic syndrome: lessons from the fructose-fed rat model | Q36720577 | ||
| Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation | Q36747890 | ||
| Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes | Q36756469 | ||
| Intermuscular adipose tissue is associated with monocyte chemoattractant protein-1, independent of visceral adipose tissue | Q36772396 | ||
| Chronic Angiotensin-(1-7) Improves Insulin Sensitivity in High-Fat Fed Mice Independent of Blood Pressure. | Q36803321 | ||
| Effect of protein, unsaturated fat, and carbohydrate intakes on plasma apolipoprotein B and VLDL and LDL containing apolipoprotein C-III: results from the OmniHeart Trial | Q36807147 | ||
| siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle | Q36807616 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | insulin resistance | Q1053470 |
| obesity | Q12174 | ||
| P304 | page(s) | 43-54 | |
| P577 | publication date | 2017-01-03 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Skeletal muscle inflammation and insulin resistance in obesity. | |
| P478 | volume | 127 |
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