Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.

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Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. is …
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scholarly articleQ13442814

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P356DOI10.7554/ELIFE.25100
P932PMC publication ID5526668
P698PubMed publication ID28738969

P50authorMagdalena SteinrueckQ88592311
Călin C GuetQ88592314
P2093author name stringMagdalena Steinrueck
P2860cites workOrganised genome dynamics in the Escherichia coli species results in highly diverse adaptive pathsQ21090212
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collectionQ22122301
Effect of chromosomal position on amplification of transfected genes in animal cellsQ22122413
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell lineQ24338329
Selfish operons: horizontal transfer may drive the evolution of gene clustersQ24533213
Q&A;: Evolutionary capacitanceQ24632731
Genomic analysis of a key innovation in an experimental Escherichia coli populationQ24632912
Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loadingQ27641676
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Endless FormsQ28111897
The evolutionary significance of cis-regulatory mutationsQ28288545
Copy number change: evolving views on gene amplification.Q38120560
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinomaQ38273214
Selective silencing of foreign DNA with low GC content by the H-NS protein in SalmonellaQ38312504
Genome position and gene amplificationQ38606305
Experimental evolution reveals hidden diversity in evolutionary pathways.Q39025569
Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genesQ39476891
A Mu gin complementing function and an invertible DNA region in Escherichia coli K-12 are situated on the genetic element e14Q39968409
Termination factor Rho and its cofactors NusA and NusG silence foreign DNA in E. coliQ40752052
Gene2Oligo: oligonucleotide design for in vitro gene synthesis.Q41010791
Target site selection in transpositionQ41550231
Gene amplification and genomic plasticity in prokaryotesQ41689429
Chromosome position effects on gene expression in Escherichia coli K-12.Q41744412
Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS.Q42557087
Evolutionary rescue in a changing worldQ43688807
A retrotransposon-mediated gene duplication underlies morphological variation of tomato fruitQ44685385
Evolutionary changes in cis and trans gene regulationQ47259060
Chromatin position effects assayed by thousands of reporters integrated in parallelQ47762535
Effect of chromosome location on bacterial mutation ratesQ50111958
Evidence that gene amplification underlies adaptive mutability of the bacterial lac operonQ50128814
High fitness costs and instability of gene duplications reduce rates of evolution of new genes by duplication-divergence mechanismsQ51100202
Effects of genomic position on the expression of transduced copies of the white gene of Drosophila.Q52457429
Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphomaQ70449918
Nonrandom location of IS1 elements in the genomes of natural isolates of Escherichia coliQ73492558
Genome-wide selection for increased copy number in Acinetobacter baylyi ADP1: locus and context-dependent variation in gene amplificationQ83161264
Recombineering: genetic engineering in bacteria using homologous recombinationQ87682799
Recombineering: a homologous recombination-based method of genetic engineeringQ28307909
The probability of evolutionary rescue: towards a quantitative comparison between theory and evolution experimentsQ28710078
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elementsQ29615996
REPuter: the manifold applications of repeat analysis on a genomic scaleQ29617500
Insertion sequencesQ29617579
Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies of bacteriaQ30731601
Exact and Asymptotic Weighted Logrank Tests for Interval Censored Data: The interval R package.Q30857508
Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseqQ30872404
Cooperation is fleeting in the world of transposable elementsQ33265216
A novel mechanism of transposon-mediated gene activationQ33510907
Site-specific chromosomal integration of large synthetic constructsQ33760274
Dosage compensation via transposable element mediated rewiring of a regulatory networkQ33861803
Mutation frequencies and antibiotic resistanceQ33945503
Distribution and abundance of insertion sequences among natural isolates of Escherichia coli.Q33952758
Rho-dependent terminators and transcription terminationQ33999162
Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coliQ34025067
Network-level architecture and the evolutionary potential of underground metabolism.Q34060771
Unprecedented high-resolution view of bacterial operon architecture revealed by RNA sequencingQ34165431
Fitness landscape transformation through a single amino acid change in the rho terminatorQ34302180
Emergent properties of reduced-genome Escherichia coli.Q34518764
Microbial laboratory evolution in the era of genome-scale scienceQ35176401
Spontaneous tandem genetic duplications in Salmonella typhimurium arise by unequal recombination between rRNA (rrn) cistronsQ35364956
The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteriaQ35482558
Opposing effects of target overexpression reveal drug mechanismsQ35535319
Rapid, accurate, computational discovery of Rho-independent transcription terminators illuminates their relationship to DNA uptakeQ35751629
Genomic islands in pathogenic and environmental microorganismsQ35752419
Selection for gene clustering by tandem duplicationQ35919829
Distribution of DNA insertion element IS5 in natural isolates of Escherichia coliQ36273205
Drug resistance gene amplification of plasmid NR1 derivatives with various amounts of resistance determinant DNAQ36292008
On the mutational topology of the bacterial genomeQ36642223
Gene amplification and adaptive evolution in bacteria.Q37580926
Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropicaQ37608616
The predictability of molecular evolution during functional innovation.Q37612743
Gene amplification and insecticide resistanceQ37672953
P407language of work or nameEnglishQ1860
P577publication date2017-07-25
P1433published ineLifeQ2000008
P1476titleComplex chromosomal neighborhood effects determine the adaptive potential of a gene under selection
P478volume6

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cites work (P2860)
Q90171629Gene amplification as a form of population-level gene expression regulation
Q58773305Leaky resistance and the conditions for the existence of lytic bacteriophage
Q46246927Living Organisms Author Their Read-Write Genomes in Evolution
Q60916118Predicting mutational routes to new adaptive phenotypes
Q60301258Single-cell copy number variant detection reveals the dynamics and diversity of adaptation

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