Icarisid II inhibits the proliferation of human osteosarcoma cells by inducing apoptosis and cell cycle arrest

scientific article published on June 2017

Icarisid II inhibits the proliferation of human osteosarcoma cells by inducing apoptosis and cell cycle arrest is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1010428317705745
P698PubMed publication ID28621234

P2093author name stringXiao Zhang
Yun Liu
Neng Jiang
Feifei Huang
Mao Xie
Jingjing Lu
Yuanyuan Tang
Ruishan Li
Shijie Liao
P2860cites workCancer Therapy with Natural Products and Medicinal PlantsQ58596478
Targeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer CellsQ26798203
Apoptosis: mechanisms and relevance in cancerQ28263388
CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45Q28469491
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosisQ29617776
Natural products as antimitotic agents.Q35461124
α-Carboline derivative TJY-16 inhibits tumor growth by inducing G2/M cell cycle arrest in glioma cellsQ35898306
Novel mechanism of harmaline on inducing G2/M cell cycle arrest and apoptosis by up-regulating Fas/FasL in SGC-7901 cellsQ36382753
Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line.Q36489832
Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cellsQ36520319
Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cellsQ37317409
Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell lineQ37478131
The role of physical therapy and occupational therapy in the rehabilitation of pediatric and adolescent patients with osteosarcomaQ37705074
Icariin: does it have an osteoinductive potential for bone tissue engineering?Q38119188
Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba EpimediiQ38336997
Tumor-suppressor Genes, Cell Cycle Regulatory Checkpoints, and the SkinQ38537584
Icariin regulates the proliferation and apoptosis of human ovarian cancer cells through microRNA-21 by targeting PTEN, RECK and Bcl-2.Q38890575
Icariin enhances cytotoxicity of doxorubicin in human multidrug-resistant osteosarcoma cells by inhibition of ABCB1 and down-regulation of the PI3K/Akt pathwayQ38902645
Comparative Pharmacokinetics Study of Icariin and Icariside II in RatsQ38935755
Synergistic Anti-Cancer Effects of Icariin and Temozolomide in GlioblastomaQ38941438
Icariside II inhibits cell proliferation and induces cell cycle arrest through the ROS-p38-p53 signaling pathway in A375 human melanoma cellsQ38946323
Blockade of epidermal growth factor receptor/mammalian target of rapamycin pathway by Icariside II results in reduced cell proliferation of osteosarcoma cellsQ38966459
MART-10, a novel vitamin D analog, inhibits head and neck squamous carcinoma cells growth through cell cycle arrest at G0/G1 with upregulation of p21 and p27 and downregulation of telomerase.Q39094656
Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cellsQ39133977
Icariside II induces apoptosis of melanoma cells through the downregulation of survival pathwaysQ39201613
Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosisQ39314663
Icariside II-induced mitochondrion and lysosome mediated apoptosis is counterbalanced by an autophagic salvage response in hepatoblastomaQ40789386
Activation of the Mitochondrial Apoptotic Signaling Platform during Rubella Virus InfectionQ40857658
Evasion of p53 and G2/M checkpoints are characteristic of Hh-driven basal cell carcinoma.Q42439705
The influence of arsenic trioxide on the cell cycle, apoptosis and expression of cyclin D1 in the Jurkat cell line.Q44556200
Osteoblastic proliferative activity of Epimedium brevicornum MaximQ46438063
Icariin Acts as a Potential Agent for Preventing Cardiac Ischemia/Reperfusion Injury.Q54291807
Osteosarcoma: better treatment through better trial design.Q54293495
P433issue6
P304page(s)1010428317705745
P577publication date2017-06-01
P1433published inTumor BiologyQ15757842
P1476titleIcarisid II inhibits the proliferation of human osteosarcoma cells by inducing apoptosis and cell cycle arrest
P478volume39

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cites work (P2860)
Q52656052Anti-Cancer Activity of Lobaric Acid and Lobarstin Extracted from the Antarctic Lichen Stereocaulon alpnum.
Q92237924Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese Medicines
Q58699818Circular RNAs hsa_circ_0032462, hsa_circ_0028173, hsa_circ_0005909 are predicted to promote CADM1 expression by functioning as miRNAs sponge in human osteosarcoma
Q64250036Improved Pharmacokinetics of Icariin (ICA) within Formulation of PEG-PLLA/PDLA-PNIPAM Polymeric Micelles
Q58696470Synthesis and Biological Evaluation of Novel Alkyl Amine Substituted Icariside II Derivatives as Potential Anticancer Agents
Q92573018Vitamin C promotes the proliferation and effector functions of human γδ T cells