Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules.

scientific article published on 15 May 2017

Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.24490
P932PMC publication ID5459574
P698PubMed publication ID28504639

P50authorCharles V SindelarQ88063660
P2093author name stringXueqi Liu
Zhiguo Shang
Daifei Liu
P2860cites workCrystal structure of the kinesin motor domain reveals a structural similarity to myosinQ24601210
An atomic-level mechanism for activation of the kinesin molecular motorsQ24625687
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High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformationsQ24676249
Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopyQ27639750
The beginning of kinesin's force-generating cycle visualized at 9-A resolutionQ27644653
Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesinQ27652263
The Ndc80 kinetochore complex forms oligomeric arrays along microtubulesQ27665013
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.Q27677990
Structure of a kinesin-tubulin complex and implications for kinesin motilityQ27685260
The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movementQ27696177
The crystal structure of dimeric kinesin and implications for microtubule-dependent motilityQ27748779
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The way things move: looking under the hood of molecular motor proteinsQ29617532
A structural change in the kinesin motor protein that drives motilityQ29617533
FREALIGN: high-resolution refinement of single particle structuresQ30080020
Three-dimensional reconstruction of helical polymersQ30300082
Kinesin processivity is gated by phosphate releaseQ30591033
Nucleotide-dependent single- to double-headed binding of kinesinQ31832889
New data on the microtubule surface latticeQ33398304
Equilibrium and transition between single- and double-headed binding of kinesin as revealed by single-molecule mechanicsQ34180438
Thermodynamic properties of the kinesin neck-region docking to the catalytic coreQ34180642
Kinesins and cancer.Q34289839
Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strainQ34650081
Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head-Nkin neck chimera with conventional kinesin.Q35116683
Large conformational changes in a kinesin motor catalyzed by interaction with microtubulesQ35128890
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins.Q35173188
A universal pathway for kinesin steppingQ35199246
High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generationQ35247680
X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon bindingQ35590409
Examining kinesin processivity within a general gating framework.Q35676931
Kinetics of nucleotide-dependent structural transitions in the kinesin-1 hydrolysis cycleQ36435280
Avoiding the pitfalls of single particle cryo-electron microscopy: Einstein from noiseQ37318148
Walking the walk: how kinesin and dynein coordinate their stepsQ37380209
A new look at the microtubule binding patterns of dimeric kinesinsQ39534405
Configuration of the two kinesin motor domains during ATP hydrolysisQ44582779
Crystal structure of the motor domain of the kinesin-related motor ncd.Q46107252
Direct observation of intermediate states during the stepping motion of kinesin-1.Q51480372
Least Median of Squares RegressionQ57380603
Microtubule structure at 8 A resolutionQ78364964
P407language of work or nameEnglishQ1860
P921main subject3D reconstructionQ4464732
P577publication date2017-05-15
P1433published ineLifeQ2000008
P1476titleStructural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules
P478volume6

Reverse relations

cites work (P2860)
Q90695741A microtubule RELION-based pipeline for cryo-EM image processing
Q88909331An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules
Q48047394Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity
Q53690747KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics.
Q52695054Kinesin-2 motors: Kinetics and biophysics.
Q64280797Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity
Q49790893The actin filament twist changes abruptly at boundaries between bare and cofilin-decorated segments

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