MCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells

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MCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1086248645
P356DOI10.1038/ONC.2017.167
P698PubMed publication ID28650465

P2093author name stringH Yang
J Wang
H Zhang
Q Huang
X Guo
L Ji
Y Wu
J Zhu
M Jin
J Xing
T Ren
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The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunitQ28591017
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Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survivalQ33573447
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Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinomaQ36109796
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Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25Q36518486
The signaling mechanism of ROS in tumor progressionQ36679538
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The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α.Q36895350
Probing novel roles of the mitochondrial uniporter in ovarian cancer cells using nanoparticlesQ36929055
Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cellsQ36973744
NAD+ and NADH in ischemic brain injuryQ36992054
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathwaysQ37041562
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen speciesQ37107583
Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and -independent mannersQ37472766
Signal integration by JNK and p38 MAPK pathways in cancer developmentQ37560607
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P577publication date2017-06-26
P1433published inOncogeneQ1568657
P1476titleMCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells

Reverse relations

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