scholarly article | Q13442814 |
P50 | author | Chaochu Cui | Q89025723 |
Liwu Fu | Q91884275 | ||
P2093 | author name string | Jianbo Yang | |
Xianwei Wang | |||
Mingyong Wang | |||
P2860 | cites work | X-ray and cryo-EM structures of the mitochondrial calcium uniporter | Q57181877 |
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Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria | Q72593109 | ||
Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells | Q74372693 | ||
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Targeting Orai1-mediated store-operated calcium entry by RP4010 for anti-tumor activity in esophagus squamous cell carcinoma | Q89125272 | ||
Cryo-EM structure of a mitochondrial calcium uniporter | Q89324271 | ||
MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+ | Q90785236 | ||
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MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake | Q24294670 | ||
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival | Q24301822 | ||
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism | Q24304898 | ||
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter | Q24306825 | ||
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter | Q24306850 | ||
MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity | Q24338031 | ||
EMRE is an essential component of the mitochondrial calcium uniporter complex | Q24339589 | ||
Mitochondrial calcium signalling and cell death: approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis | Q24649875 | ||
A mitochondrial protein compendium elucidates complex I disease biology | Q24655079 | ||
The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications | Q26824036 | ||
Targeting mitochondria metabolism for cancer therapy | Q27027219 | ||
CCDC90A (MCUR1) is a cytochrome c oxidase assembly factor and not a regulator of the mitochondrial calcium uniporter | Q27938400 | ||
Metabolic pathways promoting cancer cell survival and growth | Q28086940 | ||
Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex | Q28115674 | ||
MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics | Q28116180 | ||
MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter | Q28116907 | ||
The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake | Q28118964 | ||
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis | Q28240946 | ||
Mitochondrial fusion and fission in cell life and death | Q28299119 | ||
Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons | Q28482116 | ||
MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling | Q28486060 | ||
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia | Q28585666 | ||
The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit | Q28591017 | ||
CaMKII determines mitochondrial stress responses in heart | Q28591986 | ||
MCU encodes the pore conducting mitochondrial calcium currents | Q29347552 | ||
Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses | Q29616076 | ||
Mitochondria and cancer | Q29616610 | ||
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity | Q29616651 | ||
Calcium signaling | Q29617338 | ||
Mitochondrial control of cell death | Q29617739 | ||
Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter | Q33974822 | ||
Mitochondrial calcium transport: mechanisms and functions | Q34104032 | ||
Mitochondria and calcium signaling | Q34441267 | ||
After half a century mitochondrial calcium in- and efflux machineries reveal themselves | Q35422412 | ||
Calcium uptake by rat kidney mitochondria | Q36441249 | ||
Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25 | Q36518486 | ||
Effective killing of leukemia cells by the natural product OSW-1 through disruption of cellular calcium homeostasis | Q36579514 | ||
Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming | Q36702104 | ||
Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition | Q36770526 | ||
Cloning of two isoforms of the rat brain Na(+)-Ca2+ exchanger gene and their functional expression in HeLa cells | Q36778221 | ||
Ion channels in death and differentiation of prostate cancer cells. | Q36811138 | ||
Minocycline: far beyond an antibiotic | Q36836358 | ||
Calcium and cancer: targeting Ca2+ transport | Q36856463 | ||
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α. | Q36895350 | ||
Probing novel roles of the mitochondrial uniporter in ovarian cancer cells using nanoparticles | Q36929055 | ||
Mitochondrial complex III regulates hypoxic activation of HIF. | Q37064874 | ||
Mitochondria: the hub of cellular Ca2+ signaling | Q37133622 | ||
Mitochondrial control of calcium-channel gating: a mechanism for sustained signaling and transcriptional activation in T lymphocytes | Q37253977 | ||
Activity of the mitochondrial calcium uniporter varies greatly between tissues | Q37281674 | ||
The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria | Q37294307 | ||
Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis | Q37878020 | ||
Mitochondrial Ca(2+) and apoptosis | Q38000429 | ||
Mitochondria as sensors and regulators of calcium signalling | Q38031124 | ||
MCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells | Q38709048 | ||
Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter | Q38888678 | ||
Mitochondrial Ca²⁺ uniporter is critical for store-operated Ca²⁺ entry-dependent breast cancer cell migration. | Q38914237 | ||
Targeting calcium signaling in cancer therapy | Q39101957 | ||
Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells. | Q39163399 | ||
Mitochondrial modulation decreases the bortezomib-resistance in multiple myeloma cells | Q39184945 | ||
Interplay of reactive oxygen species, intracellular Ca2+ and mitochondrial homeostasis in the apoptosis of prostate cancer cells by deoxypodophyllotoxin | Q39236166 | ||
PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells | Q39376053 | ||
Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations | Q39445564 | ||
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. | Q39676476 | ||
Store-operated Ca2+ entry depends on mitochondrial Ca2+ uptake | Q39693203 | ||
The in vivo inhibition of tumor growth by ruthenium red: its relationship with the metabolism of calcium in the tumor | Q39737590 | ||
Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. | Q39764384 | ||
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis | Q39888627 | ||
The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter. | Q40217577 | ||
Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/bortezomib) cytotoxicity in myeloma cell lines | Q40427680 | ||
Mitochondrial calcium uniporter, MiRNA and cancer: Live and let die. | Q40768860 | ||
DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter | Q41024258 | ||
ER-mitochondria signaling regulates autophagy | Q41138057 | ||
KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I. | Q41539954 | ||
Mitofusin-2 triggers mitochondria Ca2+ influx from the endoplasmic reticulum to induce apoptosis in hepatocellular carcinoma cells | Q41581462 | ||
MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter | Q41976396 | ||
HINT2 triggers mitochondrial Ca2+ influx by regulating the mitochondrial Ca2+ uniporter (MCU) complex and enhances gemcitabine apoptotic effect in pancreatic cancer | Q41994387 | ||
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters | Q42660436 | ||
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes | Q42660454 | ||
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview | Q42660459 | ||
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Other ion channels | Q42660466 | ||
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels. | Q42660492 | ||
The mitochondrial calcium uniporter is a highly selective ion channel. | Q44737530 | ||
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation | Q46302560 | ||
Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity. | Q46408932 | ||
Doxycycline as Potential Anti-Cancer Agent. | Q46510547 | ||
Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells. | Q46952740 | ||
MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU. | Q47118758 | ||
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY. | Q47139831 | ||
Mitochondrial calcium uniporter as a target of microRNA-340 and promoter of metastasis via enhancing the Warburg effect. | Q47143083 | ||
Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening | Q47935016 | ||
Ca2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition | Q48061561 | ||
High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter. | Q48276594 | ||
Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy | Q50089772 | ||
Dynamics of mitochondrial Ca2+ uptake in MICU1-knockdown cells. | Q50482635 | ||
Therapeutic advantage of combining calcium channel blockers and TRAIL in prostate cancer. | Q52573066 | ||
Calcium orchestrates apoptosis. | Q54055382 | ||
RIPK1 binds MCU to mediate induction of mitochondrial Ca2+ uptake and promote colorectal oncogenesis. | Q54121779 | ||
P433 | issue | 9 | |
P304 | page(s) | 1190-1205 | |
P577 | publication date | 2019-04-03 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Progress in understanding mitochondrial calcium uniporter complex-mediated calcium signalling: A potential target for cancer treatment | |
P478 | volume | 176 |