A polyvalent hybrid protein elicits antibodies against the diverse allelic types of block 2 in Plasmodium falciparum merozoite surface protein 1.

scientific article published on 04 August 2011

A polyvalent hybrid protein elicits antibodies against the diverse allelic types of block 2 in Plasmodium falciparum merozoite surface protein 1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2011.07.106
P932PMC publication ID3195258
P698PubMed publication ID21820475
P5875ResearchGate publication ID51550973

P50authorDavid J. ConwayQ30347162
P2093author name stringKevin K A Tetteh
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Extensive antigenic polymorphism within the repeat sequence of the Plasmodium falciparum merozoite surface protein 1 block 2 is incorporated in a minimal polyvalent immunogenQ39518664
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Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1.Q48036521
In vivo induction of type 1 and 2 immune responses against protein antigensQ73312323
Molecular identification of a malaria merozoite surface sheddaseQ24811597
Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1Q28743564
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RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infectionQ33251913
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Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasionQ33761687
Characterization of conserved T- and B-cell epitopes in plasmodium falciparum major merozoite surface protein 1Q34004267
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Regulated maturation of malaria merozoite surface protein‐1 is essential for parasite growthQ34369560
Repeat sequences in block 2 of Plasmodium falciparum merozoite surface protein 1 are targets of antibodies associated with protection from malariaQ34855814
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Genetic diversity in the Block 2 region of the merozoite surface protein 1 (MSP-1) of Plasmodium falciparum: additional complexity and selection and convergence in fragment size polymorphismQ35754182
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Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1Q36313955
A new rodent model to assess blood stage immunity to the Plasmodium falciparum antigen merozoite surface protein 119 reveals a protective role for invasion inhibitory antibodiesQ36371697
Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malariaQ36594057
A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbitsQ36710710
The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria.Q37559892
The malaria merozoite, forty years on.Q37568142
Antibodies to the N-terminal block 2 of plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malariaQ37582802
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectPlasmodium falciparumQ311383
P304page(s)7811-7817
P577publication date2011-08-04
P1433published inVaccineQ7907941
P1476titleA polyvalent hybrid protein elicits antibodies against the diverse allelic types of block 2 in Plasmodium falciparum merozoite surface protein 1.
P478volume29

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cites work (P2860)
Q57059017An expanded global inventory of allelic variation in the most extremely polymorphic region of Plasmodium falciparum merozoite surface protein 1 provided by short read sequence data
Q37264614Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity
Q59795795Diversity analysis of MSP1 identifies conserved epitope organization in block 2 amidst high sequence variability in Indian Plasmodium falciparum isolates
Q37704962Genetic diversity of MSP1 Block 2 of Plasmodium vivax isolates from Manaus (central Brazilian Amazon).
Q90435715Genetic diversity of Plasmodium falciparum and genetic profile in children affected by uncomplicated malaria in Cameroon
Q37352099High levels of IgG3 anti ICB2-5 in Plasmodium vivax-infected individuals who did not develop symptoms
Q38159694N-terminal Plasmodium vivax merozoite surface protein-1, a potential subunit for malaria vivax vaccine
Q26853267Paths to a malaria vaccine illuminated by parasite genomics

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