scholarly article | Q13442814 |
P50 | author | Michael J Blackman | Q56786712 |
Chrislaine Withers-Martinez | Q87837775 | ||
Fiona Hackett | Q107404870 | ||
P2093 | author name string | Sharon Yeoh | |
Anton R Dluzewski | |||
Graham H Mitchell | |||
Lawrence H Bannister | |||
Rebecca A O'Donnell | |||
Philippa K Harris | |||
P2860 | cites work | Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments. | Q52455490 |
Cytochalasin D does not produce net depolymerization of actin filaments in HEp-2 cells. | Q52503934 | ||
Functional analysis of the propeptide of subtilisin E as an intramolecular chaperone for protein folding. Refolding and inhibitory abilities of propeptide mutants. | Q54601480 | ||
Expression of the 19-kilodalton carboxy-terminal fragment of the Plasmodium falciparum merozoite surface protein-1 in Escherichia coli as a correctly folded protein. | Q54638975 | ||
Actin Microfilaments Facilitate the Retrograde Transport from the Golgi Complex to the Endoplasmic Reticulum in Mammalian Cells | Q58493556 | ||
Processing of thePlasmodium falciparum major merozoite surface protein-1: identification of a 33-kilodalton secondary processing product which is shed prior to erythrocyte invasion | Q59394239 | ||
Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondii | Q63409196 | ||
The synthesis and analytical use of a highly sensitive and convenient substrate of elastase | Q68827466 | ||
Secretion of micronemal proteins is associated with toxoplasma invasion of host cells | Q73510453 | ||
Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development | Q73764830 | ||
A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies. | Q36352078 | ||
Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling | Q38288459 | ||
Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite | Q39600996 | ||
Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii | Q39647004 | ||
Purification of Plasmodium falciparum merozoites for analysis of the processing of merozoite surface protein-1. | Q40501263 | ||
Apical membrane antigen 1, a major malaria vaccine candidate, mediates the close attachment of invasive merozoites to host red blood cells | Q40582637 | ||
Induction of secretion and surface capping of microneme proteins in Eimeria tenella | Q40843439 | ||
Proprotein convertase PC1/3-related peptides are potent slow tight-binding inhibitors of murine PC1/3 and Hfurin | Q42059728 | ||
Inhibition of actin polymerization by latrunculin A. | Q42217562 | ||
Vectors for the expression of tagged proteins in Schizosaccharomyces pombe. | Q42543117 | ||
Mode of action of invasion-inhibitory antibodies directed against apical membrane antigen 1 of Plasmodium falciparum | Q42727356 | ||
1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase | Q43016000 | ||
A sensitive new substrate for chymotrypsin | Q44163410 | ||
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage | Q44397889 | ||
Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum | Q44588579 | ||
Active intranuclear movement of herpesvirus capsids | Q46415497 | ||
Malaria parasite actin filaments are very short | Q46474283 | ||
PfSUB-2: a second subtilisin-like protein in Plasmodium falciparum merozoites | Q47855436 | ||
PCR-based gene synthesis as an efficient approach for expression of the A+T-rich malaria genome. | Q47857173 | ||
Functional conservation of the malaria vaccine antigen MSP-119across distantly related Plasmodium species | Q47857319 | ||
Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species | Q47874885 | ||
Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. | Q47884690 | ||
Gene targeting demonstrates that the Plasmodium berghei subtilisin PbSUB2 is essential for red cell invasion and reveals spontaneous genetic recombination events. | Q47971767 | ||
Crystal structure of the malaria vaccine candidate apical membrane antigen 1. | Q48004368 | ||
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens | Q48013866 | ||
A conserved parasite serine protease processes the Plasmodium falciparum merozoite surface protein-1. | Q48014494 | ||
Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray | Q24804829 | ||
Latrunculin alters the actin-monomer subunit interface to prevent polymerization | Q27624918 | ||
Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus | Q27639322 | ||
Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin | Q27642831 | ||
The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 A resolution | Q27766005 | ||
How to measure and predict the molar absorption coefficient of a protein | Q27860551 | ||
Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites | Q27973516 | ||
Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase | Q27973702 | ||
A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle | Q27974188 | ||
Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment | Q28640526 | ||
Discovery of gene function by expression profiling of the malaria parasite life cycle | Q29547840 | ||
Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set | Q29616463 | ||
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil | Q29619882 | ||
Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1 | Q30043446 | ||
Actin filament polymerization regulates gliding motility by apicomplexan parasites | Q30477554 | ||
Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii | Q30765884 | ||
Inhibitory potency and specificity of subtilase-like pro-protein convertase (SPC) prodomains | Q30769503 | ||
Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex | Q31050217 | ||
Structure and invasive behaviour ofPlasmodium knowlesimerozoitesin vitro | Q31060680 | ||
A co-ligand complex anchors Plasmodium falciparum merozoites to the erythrocyte invasion receptor band 3. | Q33195225 | ||
A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma | Q33932480 | ||
Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasion | Q33938442 | ||
Antibodies against thrombospondin-related anonymous protein do not inhibit Plasmodium sporozoite infectivity in vivo | Q34004839 | ||
Mix and match modules: structure and function of microneme proteins in apicomplexan parasites. | Q34167780 | ||
Proteases involved in erythrocyte invasion by the malaria parasite: function and potential as chemotherapeutic targets | Q34320843 | ||
The global distribution and population at risk of malaria: past, present, and future | Q34548302 | ||
Band 3 is a host receptor binding merozoite surface protein 1 during thePlasmodium falciparuminvasion of erythrocytes | Q34982236 | ||
Proteolysis within the membrane: rhomboids revealed | Q35678316 | ||
Role of proteases in host cell invasion by Toxoplasma gondii and other Apicomplexa | Q35781639 | ||
Subtilisin-like proteases of the malaria parasite. | Q35822049 | ||
Molecular and functional aspects of parasite invasion | Q35937482 | ||
A new release on life: emerging concepts in proteolysis and parasite invasion | Q36063959 | ||
Dense granules: are they key organelles to help understand the parasitophorous vacuole of all apicomplexa parasites? | Q36174886 | ||
Interaction between cytochalasin B-treated malarial parasites and erythrocytes. Attachment and junction formation | Q36341089 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | malaria | Q12156 |
merozoite | Q2296434 | ||
subtilisin-like protease 2 | Q56576371 | ||
subtilisin-like protease 2, putative | Q56734511 | ||
subtilisin-like protease 2, putative | Q59744999 | ||
subtilisin-like protease 2, putative | Q59879520 | ||
subtilisin-like protease 2 | Q59913444 | ||
subtilisin-like protease 2, putative | Q59959982 | ||
subtilisin-like protease 2, putative | Q59972382 | ||
subtilisin-like protease 2, putative | Q59985821 | ||
subtilisin-like protease 2, putative | Q59992683 | ||
subtilisin-like protease 2, putative | Q59999538 | ||
subtilisin-like protease 2, putative | Q61614328 | ||
P304 | page(s) | 241-51 | |
P577 | publication date | 2005-11-01 | |
P1433 | published in | PLOS Pathogens | Q283209 |
P1476 | title | Molecular identification of a malaria merozoite surface sheddase | |
P478 | volume | 1 |
Q59985821 | subtilisin-like protease 2, putative |
Q59992683 | subtilisin-like protease 2, putative |
Q59999538 | subtilisin-like protease 2, putative |
Q56734511 | subtilisin-like protease 2, putative |
Q59744999 | subtilisin-like protease 2, putative |
Q59879520 | subtilisin-like protease 2, putative |
Q59972382 | subtilisin-like protease 2, putative |
Q28474023 | A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates |
Q87837788 | A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1. |
Q30043444 | A multifunctional serine protease primes the malaria parasite for red blood cell invasion |
Q47597994 | A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress |
Q27695596 | A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase |
Q38729151 | A polyvalent hybrid protein elicits antibodies against the diverse allelic types of block 2 in Plasmodium falciparum merozoite surface protein 1. |
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Q33761687 | Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasion |
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