Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole

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Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1002197
P932PMC publication ID3164628
P698PubMed publication ID21909259
P5875ResearchGate publication ID51640666

P50authorIset Medina VeraQ56816875
Kami KimQ38640337
P2093author name stringWandy L Beatty
Photini Sinnis
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Rhomboid 4 (ROM4) affects the processing of surface adhesins and facilitates host cell invasion by Toxoplasma gondiiQ27315046
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Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondiiQ27972559
Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malariaQ27972762
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Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasiteQ30043432
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No TRAP, no invasionQ37356195
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Host cell traversal is important for progression of the malaria parasite through the dermis to the liverQ44140408
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The large difference in infectivity for mice of Plasmodium berghei and Plasmodium yoelii sporozoites cannot be correlated with their ability to enter into hepatocytesQ44173638
Identification of trafficking determinants for polytopic rhomboid proteases in Toxoplasma gondiiQ44175631
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavageQ44397889
Apicomplexan rhomboids have a potential role in microneme protein cleavage during host cell invasionQ46507314
Improved transfection and new selectable markers for the rodent malaria parasite Plasmodium yoeliiQ46927846
Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells.Q47837790
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Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogensQ48013866
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectvacuoleQ127702
P304page(s)e1002197
P577publication date2011-09-01
P1433published inPLOS PathogensQ283209
P1476titlePlasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole
P478volume7

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cites work (P2860)
Q28551592A Trichomonas vaginalis Rhomboid Protease and Its Substrate Modulate Parasite Attachment and Cytolysis of Host Cells
Q37160400Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage
Q41100689Entamoeba histolytica rhomboid protease 1 has a role in migration and motility as validated by two independent genetic approaches
Q38790377Intramembrane proteases as drug targets
Q34332951Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.
Q37533146Malaria parasite pre-erythrocytic infection: preparation meets opportunity
Q38260909New insight-guided approaches to detect, cure, prevent and eliminate malaria
Q34507085Plasmodium berghei Δp52&p36 parasites develop independent of a parasitophorous vacuole membrane in Huh-7 liver cells
Q36644236Pre-erythrocytic malaria vaccines: identifying the targets
Q39362514Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation
Q37706424Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets.
Q38083850Structural and mechanistic principles of intramembrane proteolysis--lessons from rhomboids
Q26829687The roles of intramembrane proteases in protozoan parasites
Q37049536Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins
Q36832448Total and putative surface proteomics of malaria parasite salivary gland sporozoites.
Q57987392Toxin-Antitoxin Systems in Bacteria and Archaea
Q35903853Translational Control of UIS4 Protein of the Host-Parasite Interface Is Mediated by the RNA Binding Protein Puf2 in Plasmodium berghei Sporozoites

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