| scholarly article | Q13442814 |
| P356 | DOI | 10.1080/0284186X.2017.1301680 |
| P698 | PubMed publication ID | 28358664 |
| P50 | author | Yogendra S Padwad | Q52762001 |
| Sourabh Soni | Q87706930 | ||
| P2093 | author name string | Yogendra S Padwad | |
| Sourabh Soni | |||
| P2860 | cites work | Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. | Q51256046 |
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| C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation | Q24291783 | ||
| A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation | Q24294741 | ||
| Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide | Q24302071 | ||
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| Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803 | Q24306213 | ||
| Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
| Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth | Q24603549 | ||
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| Purification and characterization of hypoxia-inducible factor 1 | Q28678375 | ||
| Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes | Q29617594 | ||
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| Succinate is an inflammatory signal that induces IL-1β through HIF-1α. | Q33652731 | ||
| Bcl-2 Family Members and Functional Electron Transport Chain Regulate Oxygen Deprivation-Induced Cell Death | Q34290708 | ||
| The role of melanogenesis in regulation of melanoma behavior: melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways. | Q34459021 | ||
| Insulin Regulates Hypoxia-Inducible Factor-1α Transcription by Reactive Oxygen Species Sensitive Activation of Sp1 in 3T3-L1 Preadipocyte | Q34692769 | ||
| Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells | Q34752692 | ||
| Targeting HIF1α eliminates cancer stem cells in hematological malignancies. | Q34887224 | ||
| Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization | Q35006577 | ||
| Reciprocal influence of the p53 and the hypoxic pathways | Q35065006 | ||
| Differential effects of HIF-α isoforms on apoptosis in renal carcinoma cell lines. | Q35127783 | ||
| The role of the HIF-1α transcription factor in increased cell division at physiological oxygen tensions. | Q35169937 | ||
| Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation | Q35239845 | ||
| The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop | Q35410718 | ||
| RETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs | Q35571699 | ||
| Hypoxia-inducible factors in cancer stem cells and inflammation | Q35705992 | ||
| Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia | Q35779246 | ||
| HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells | Q35849333 | ||
| HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs | Q35863978 | ||
| HIF-1 at the crossroads of hypoxia, inflammation, and cancer | Q36070195 | ||
| Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition: Robust New Target or Another Big Bust for Stroke Therapeutics? | Q36079321 | ||
| Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy | Q36220497 | ||
| HIF-1α pathway: role, regulation and intervention for cancer therapy | Q36238647 | ||
| PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation | Q36439595 | ||
| miR-21 Is Linked to Glioma Angiogenesis: A Co-Localization Study | Q36742601 | ||
| The metastatic niche: adapting the foreign soil | Q36928869 | ||
| Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis | Q37132758 | ||
| Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart | Q37256152 | ||
| bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death | Q37468673 | ||
| Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression | Q37469223 | ||
| PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression | Q37495576 | ||
| Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene | Q37541263 | ||
| HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms. | Q37581909 | ||
| Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia | Q37591415 | ||
| Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α. | Q37599925 | ||
| Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling | Q37694105 | ||
| Metastatic stem cells: sources, niches, and vital pathways | Q37720793 | ||
| Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer | Q37731507 | ||
| Functional regulation of HIF-1α under normoxia--is there more than post-translational regulation? | Q37866715 | ||
| Regulation of Metabolism by Hypoxia-Inducible Factor 1 | Q37904524 | ||
| Oxygen sensing, homeostasis, and disease | Q37914865 | ||
| Recent agents targeting HIF‐1α for cancer therapy | Q38042021 | ||
| Oxygen-independent regulation of HIF-1: novel involvement of PI3K/AKT/mTOR pathway in cancer | Q38072462 | ||
| Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology | Q38128383 | ||
| Disrupting proton dynamics and energy metabolism for cancer therapy | Q38130850 | ||
| Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications | Q38204334 | ||
| HIF1A expression in localized prostate cancer treated with dose escalation radiation therapy | Q38388716 | ||
| Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015). | Q38735845 | ||
| Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1α stabilization/nuclear translocation in bone metastasis from breast carcinoma. | Q38935440 | ||
| Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD | Q38966981 | ||
| Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia | Q39016968 | ||
| Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses. | Q39034488 | ||
| Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism | Q39037560 | ||
| IGF-1 induced HIF-1α-TLR9 cross talk regulates inflammatory responses in glioma. | Q39506735 | ||
| Thymosin β4 induces the expression of vascular endothelial growth factor (VEGF) in a hypoxia-inducible factor (HIF)-1α-dependent manner | Q39670351 | ||
| An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells. | Q39850331 | ||
| Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells | Q40048868 | ||
| Hypoxia-inducible factor 1 alpha is essential for hypoxic p27 induction in endometrioid endometrial carcinoma | Q40055833 | ||
| Mutant p53 facilitates pro-angiogenic, hyperproliferative phenotype in response to chronic relative hypoxia | Q40228306 | ||
| The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha | Q40296392 | ||
| Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness. | Q40314191 | ||
| Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization. | Q40523929 | ||
| Anoxia-induced apoptosis occurs through a mitochondria-dependent pathway in lung epithelial cells | Q40746656 | ||
| Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha | Q41843388 | ||
| Expression of cFLIPL Determines the Basal Interaction of Bcl-2 With Beclin-1 and Regulates p53 Dependent Ubiquitination of Beclin-1 During Autophagic Stress | Q42486395 | ||
| Expression of Hypoxia Inducible Factor-1α and Its Significance in Laryngeal Carcinoma | Q42758514 | ||
| Antagonistic crosstalk between APC and HIF-1α. | Q42781272 | ||
| MicroRNAs in Hypoxia Response | Q42837550 | ||
| Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis | Q43245331 | ||
| Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. | Q43491607 | ||
| Hypoxia-inducible factor-1-regulated protein expression and oligodendroglioma patient outcome: comparison with established biomarkers and preoperative UCSF low-grade scoring system | Q43619655 | ||
| Nucleocytoplasmic shuttling of IPAS by its unique nuclear import and export signals unshared with other HIF-3α splice variants | Q43763982 | ||
| The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma | Q44043146 | ||
| Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway | Q44121094 | ||
| S-nitrosation of Cys-800 of HIF-1alpha protein activates its interaction with p300 and stimulates its transcriptional activity | Q44546927 | ||
| HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia | Q45868952 | ||
| Hypoxia-inducible factor 1 alpha in clear cell renal cell carcinoma | Q46372340 | ||
| Recommendations on the use of 18F-FDG PET in oncology | Q46744015 | ||
| Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation | Q46902040 | ||
| Loss of VHL expression contributes to epithelial-mesenchymal transition in oral squamous cell carcinoma | Q47751885 | ||
| Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation | Q48504336 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 503-515 | |
| P577 | publication date | 2017-04-01 | |
| P1433 | published in | Acta Oncologica | Q326164 |
| P1476 | title | HIF-1 in cancer therapy: two decade long story of a transcription factor | |
| P478 | volume | 56 |
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