Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi

scientific article published on 03 October 2016

Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00809-16
P932PMC publication ID5116729
P698PubMed publication ID27698021

P50authorSue-Jie KooQ57165977
Imran H ChowdhuryQ57165984
P2093author name stringBartosz Szczesny
Xianxiu Wan
Nisha J Garg
P2860cites workRelationship between long-term resistance to Trypanosoma cruzi and latent infection, examined by antibody production and polymerase chain reaction in miceQ44284328
Cruzipain, a major Trypanosoma cruzi antigen, promotes arginase-2 expression and survival of neonatal mouse cardiomyocytesQ44588538
Peripheral macrophage depletion reduces central nervous system parasitism and damage in Trypanosoma cruzi-infected suckling ratsQ44799353
Mitochondrial generation of reactive oxygen species is enhanced at the Q(o) site of the complex III in the myocardium of Trypanosoma cruzi-infected mice: beneficial effects of an antioxidant.Q46246603
In vivo macrophage function in experimental infection with Trypanosoma cruzi subpopulationsQ46964992
Protein kinase Cβ is critical for the metabolic switch to glycolysis following B-cell antigen receptor engagement.Q54482357
Polarizing macrophages through reprogramming of glucose metabolism.Q54505597
Oxygen metabolism by endothelial nitric-oxide synthaseQ57216403
Release of reactive oxygen species by phagocytic cells in response to live parasites in mice infected with Trypanosoma cruziQ58843180
A histopathological analysis of the course of myocarditis in C3H/He mice infected with Trypanosoma cruzi clone Sylvio-X10/4Q58846524
Studies of Trypanosoma cruzi clones in inbred mice. I. A comparison of the course of infection of C3H/HEN- mice with two clones isolated from a common sourceQ58847284
Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseasesQ72462338
Studies on the virulence and attenuation of Trypanosoma cruzi using immunodeficient animalsQ73356559
Griess method for nitrite measurement of aqueous and protein-containing samplesQ78659273
Phospholipase A1 from Trypanosoma cruzi infective stages generates lipid messengers that activate host cell protein kinase cQ79377210
Understanding the Warburg effect: the metabolic requirements of cell proliferationQ24604760
Interactions between Trypanosoma cruzi Secreted Proteins and Host Cell Signaling PathwaysQ26749609
Control of macrophage metabolism and activation by mTOR and Akt signalingQ26781587
Metabolic reprogramming in macrophages and dendritic cells in innate immunityQ28080815
Modulation of Trypanosoma cruzi-specific T-cell responses after chemotherapy for chronic Chagas diseaseQ28083346
Analysis and interpretation of microplate-based oxygen consumption and pH dataQ30871014
Glycolysis and the significance of lactate in traumatic brain injuryQ30938714
Respiratory burst in human neutrophilsQ33807586
Heat-killed Trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunityQ33809208
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophagesQ34071063
Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophagesQ34456390
Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins in infectivityQ34675951
Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseasesQ34755657
Interference between PARPs and SIRT1: a novel approach to healthy ageing?Q35166122
NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas diseaseQ35230292
Enhancement of macrophage microbicidal activity: supplemental arginine and citrulline augment nitric oxide production in murine peritoneal macrophages and promote intracellular killing of Trypanosoma cruziQ35425660
Multiplex Real-Time PCR Assay Using TaqMan Probes for the Identification of Trypanosoma cruzi DTUs in Biological and Clinical SamplesQ35624368
TcI Isolates of Trypanosoma cruzi Exploit the Antioxidant Network for Enhanced Intracellular Survival in Macrophages and Virulence in Mice.Q35986511
Defects of mtDNA replication impaired mitochondrial biogenesis during Trypanosoma cruzi infection in human cardiomyocytes and chagasic patients: the role of Nrf1/2 and antioxidant responseQ36519814
Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology.Q36555287
Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes.Q37399631
Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulenceQ37540773
Fighting the oxidative assault: the Trypanosoma cruzi journey to infectionQ37555693
Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitusQ37599302
Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype.Q37635856
Serum-mediated activation of macrophages reflects TcVac2 vaccine efficacy against Chagas diseaseQ37713220
Antimicrobial properties of nitric oxide and its application in antimicrobial formulations and medical devices.Q37777339
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applicationsQ37973947
A quick look at biochemistry: carbohydrate metabolismQ38107290
Macrophage-derived peroxynitrite diffusion and toxicity to Trypanosoma cruziQ40492558
Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharideQ40960914
Parasite persistence correlates with disease severity and localization in chronic Chagas' diseaseQ42605133
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma cruziQ150162
P304page(s)3527-3541
P577publication date2016-10-03
P1433published inInfection and ImmunityQ6029193
P1476titleMacrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi
P478volume84

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cites work (P2860)
Q58581532A Mutation in the Gene Alters the Physicochemical Properties of the Bacterial Cell Wall and Reduces Survival inside
Q92094072Autophagy plays a protective role against Trypanosoma cruzi infection in mice
Q60047543Disease Tolerance and Pathogen Resistance Genes May Underlie Persistence and Differential Progression to Chagas Disease Cardiomyopathy
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Q64101957Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis
Q92006449Immuno-metabolic profile of human macrophages after Leishmania and Trypanosoma cruzi infection
Q92446931MGL1 Receptor Plays a Key Role in the Control of T. cruzi Infection by Increasing Macrophage Activation through Modulation of ERK1/2, c-Jun, NF-κB and NLRP3 Pathways
Q47120125Modulation of host central carbon metabolism and in situ glucose uptake by intracellular Trypanosoma cruzi amastigotes.
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Q55040558Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages.
Q58604358Purinergic Antagonist Suramin Aggravates Myocarditis and Increases Mortality by Enhancing Parasitism, Inflammation, and Reactive Tissue Damage in -Infected Mice
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Q58705710The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease

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