Neuroprotective Effect of Low-Intensity Pulsed Ultrasound Against MPP+-Induced Neurotoxicity in PC12 Cells: Involvement of K2P Channels and Stretch-Activated Ion Channels

scientific article published on 02 June 2017

Neuroprotective Effect of Low-Intensity Pulsed Ultrasound Against MPP+-Induced Neurotoxicity in PC12 Cells: Involvement of K2P Channels and Stretch-Activated Ion Channels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ULTRASMEDBIO.2017.04.020
P698PubMed publication ID28583325

P2093author name stringLei Zhang
Yi Feng
Mingxi Wan
Lu Zhao
Aiwei Shi
Shifang Guo
P2860cites workErythropoietin prevents PC12 cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis via the Akt/GSK-3beta/caspase-3 mediated signaling pathwayQ80348243
Upgraded nerve growth factor expression induced by low-intensity continuous-wave ultrasound accelerates regeneration of neurotometicly injured sciatic nerve in ratsQ84556854
Mechanotransduction activates α₅β₁ integrin and PI3K/Akt signaling pathways in mandibular osteoblastsQ84717295
First experience with MR-guided focused ultrasound in the treatment of Parkinson's diseaseQ22001071
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.Q24533236
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
Mode & mechanism of low intensity pulsed ultrasound (LIPUS) in fracture repairQ26748811
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanismQ26751266
Prospects for new restorative and neuroprotective treatments in Parkinson's diseaseQ28138668
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's diseaseQ28210040
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseasesQ28269333
Parkinson's disease: mechanisms and modelsQ29547424
The Bcl2 family: regulators of the cellular life-or-death switchQ29614982
Oxidative stress in Parkinson's diseaseQ29618017
Ultrasound modulates ion channel currents.Q30384985
Low-intensity pulsed ultrasound treatment improved the rate of autograft peripheral nerve regeneration in rat.Q30385060
Sonogenetics is a non-invasive approach to activating neurons in Caenorhabditis elegansQ30402051
Protective effects of low-intensity pulsed ultrasound on aluminum-induced cerebral damage in Alzheimer's disease rat modelQ30413664
Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytesQ30448862
The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism.Q30473178
Redox regulation by thioredoxin superfamily; protection against oxidative stress and agingQ34173976
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disordersQ34653971
Signaling pathways for PC12 cell differentiation: making the right connectionsQ34662640
Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injuryQ34733694
The effects of LIPUS on soft-tissue healing: a review of literatureQ34881162
Neuronal survival and cell death signaling pathways.Q35063052
Ultrasound in the treatment of ischaemic strokeQ35172277
Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death.Q35680512
Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enoughQ35751844
Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotectionQ35794526
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicityQ36099803
Oxidative stress and neurotoxicityQ37021184
Control of mitochondrial apoptosis by the Bcl-2 familyQ37385623
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicityQ37683630
Eukaryotic mechanosensitive channelsQ37700685
Molecular mechanisms of pathogenesis of Parkinson's disease.Q37749063
Neurotrophic factor therapy for Parkinson’s diseaseQ37796025
Programmed cell death in Parkinson's diseaseQ38036233
Critical roles of thioredoxin in nerve growth factor-mediated signal transduction and neurite outgrowth in PC12 cells.Q38358561
Ultrasound treatment of neurological diseases--current and emerging applicationsQ38739505
Ultrasound can modulate neuronal development: impact on neurite growth and cell body morphologyQ39193541
Effects of low-intensity pulsed ultrasound on integrin-FAK-PI3K/Akt mechanochemical transduction in rabbit osteoarthritis chondrocytesQ39208021
Astaxanthin protects against MPTP/MPP+-induced mitochondrial dysfunction and ROS production in vivo and in vitroQ39634949
Overexpression of heme oxygenase-1 protects dopaminergic neurons against 1-methyl-4-phenylpyridinium-induced neurotoxicity.Q39938618
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cellsQ40725645
Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neurotoxicity in rat PC12 cellsQ40747711
Enhancement of Neurotrophic Factors in Astrocyte for Neuroprotective Effects in Brain Disorders Using Low-intensity Pulsed Ultrasound StimulationQ41626592
Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's diseaseQ42710028
Protective effects of heme oxygenase-1 against MPP(+)-induced cytotoxicity in PC-12 cellsQ43176201
Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: implications for oxidative stress and environmental factors in Parkinson's diseaseQ44807296
Assessment of PC12 cell differentiation and neurite growth: a comparison of morphological and neurochemical measuresQ44869035
Protective effects of TREK-1 against oxidative injury induced by SNP and H2O2.Q46346764
15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2.Q46385069
The BCL2 code to dopaminergic development and Parkinson's disease.Q46444138
Parkinson disease: from pathology to molecular disease mechanismsQ48177704
1-Methyl-4-phenylpyridine (MPP+) induces oxidative stress in the rodentQ48376512
The effect of ultrasound for increasing neural differentiation in hBM-MSCs and inducing neurogenesis in ischemic stroke modelQ48466948
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineQ48477579
Ultrasound Enhances the Expression of Brain-Derived Neurotrophic Factor in Astrocyte Through Activation of TrkB-Akt and Calcium-CaMK Signaling PathwaysQ48700997
Unilateral magnetic resonance-guided focused ultrasound pallidotomy for Parkinson disease.Q50241342
Activation of TREK currents by the neuroprotective agent riluzole in mouse sympathetic neurons.Q50547354
Low-Intensity Pulsed Ultrasound Enhances Nerve Growth Factor-Induced Neurite Outgrowth through Mechanotransduction-Mediated ERK1/2-CREB-Trx-1 SignalingQ51173482
Early embryonic lethality caused by targeted disruption of the mouse thioredoxin geneQ52521278
Thioredoxin, a singlet oxygen quencher and hydroxyl radical scavenger: redox independent functionsQ73080715
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1Q74162404
Low-intensity pulsed ultrasound accelerates the regeneration of the sciatic nerve after neurotomy in ratsQ78617245
Thioredoxin-1 protects against hyperoxia-induced apoptosis in cells of the alveolar wallsQ79257184
P433issue9
P921main subjectneurotoxicityQ3338704
toxic encephalopathyQ7830379
P1104number of pages14
P304page(s)1986-1999
P577publication date2017-06-02
P1433published inUltrasound in Medicine and BiologyQ2260380
P1476titleNeuroprotective Effect of Low-Intensity Pulsed Ultrasound Against MPP+-Induced Neurotoxicity in PC12 Cells: Involvement of K2P Channels and Stretch-Activated Ion Channels
P478volume43

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cites work (P2860)
Q78946260Noninvasive Ultrasound Deep Brain Stimulation for the Treatment of Parkinson's Disease Model Mouse
Q92169166Ultrasound Neuromodulation: A Review of Results, Mechanisms and Safety

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