HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis

scientific article published on 05 June 2017

HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/1878-0261.12090
P8608Fatcat IDrelease_4y2rmskhwbf5rluikwkqeej7za
P932PMC publication ID5579341
P698PubMed publication ID28580773

P50authorShaohang CaiQ56496009
P2093author name stringHong Wang
Chun-Hua Wang
Rong-Zhen Luo
Xia Yang
Dan Xie
Jing-Ping Yun
Li-Li Liu
Chris Zhiyi Zhang
Shi-Xun Lu
Shi-Lu Chen
P2860cites workAIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse modelQ24301826
Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanomaQ24320063
Hepatocellular carcinomaQ29615765
Hepatocellular carcinomaQ29616359
Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cellsQ34172711
Regulatory evolution of innate immunity through co-option of endogenous retrovirusesQ34516863
Regulation of inflammasome activationQ35456425
Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2.Q35609669
The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal ActivityQ35780700
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and CancerQ35815863
Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and AktQ35929017
Expression of AIM2 is correlated with increased inflammation in chronic hepatitis B patientsQ35986253
The molecular mechanism of breast cancer cell apoptosis induction by absent in melanoma (AIM2)Q36317303
Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome componentsQ36545181
LRG1 expression indicates unfavorable clinical outcome in hepatocellular carcinomaQ36561699
AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunityQ36592682
HBx-upregulated lncRNA UCA1 promotes cell growth and tumorigenesis by recruiting EZH2 and repressing p27Kip1/CDK2 signaling.Q36724900
Genetic determinants of cancer metastasisQ36794312
Molecular mechanisms of hepatocellular carcinomaQ37323726
Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway.Q37392672
Carboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinomaQ37688204
Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches.Q37857056
Liver cancer in 2013: Mutational landscape of HCC--the end of the beginning.Q38176242
Infection and Cancer: The Case of Hepatitis B.Q38636647
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.Q38785882
Absent in melanoma 2 proteins in the development of cancerQ38872363
Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.Q39123741
AIM2, an IFN-inducible cytosolic DNA sensor, in the development of benign prostate hyperplasia and prostate cancerQ39124275
Lipocalin-2 negatively modulates the epithelial-to-mesenchymal transition in hepatocellular carcinoma through the epidermal growth factor (TGF-beta1)/Lcn2/Twist1 pathwayQ39148912
Hepatitis B virus inhibits liver regeneration via epigenetic regulation of urokinase-type plasminogen activatorQ39181943
C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by C-Jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma.Q39310264
Upregulated FoxM1 expression induced by hepatitis B virus X protein promotes tumor metastasis and indicates poor prognosis in hepatitis B virus-related hepatocellular carcinomaQ39345201
Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cellsQ39792930
Human lung cancer-derived immunosuppressive plasmacytoid dendritic cells release IL-1α in an AIM2 inflammasome-dependent mannerQ40387174
TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective AutophagyQ40585385
The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.Q40586213
Human hepatocytes express absent in melanoma 2 and respond to hepatitis B virus with interleukin-18 expressionQ40707962
AIM2 inflammasome is dispensable for the host defense against Pseudomonas aeruginosa infectionQ40801442
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastasesQ44483781
Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentinQ45353493
Correlation of AIM2 expression in peripheral blood mononuclear cells from humans with acute and chronic hepatitis B.Q45370391
Liver inflammation and cancer: The role of tissue microenvironment in generating the tumor-promoting niche (TPN) in the development of hepatocellular carcinomaQ45880681
Differential expression of inflammasomes in lung cancer cell lines and tissues.Q51637026
AIMing 2 Curtail Cancer.Q53441543
Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patientsQ57191753
Inflammation lights the way to metastasisQ59092552
Absent in Melanoma 2 is predominantly present in primary melanoma and primary squamous cell carcinoma, but largely absent in metastases of both tumorsQ86087473
P433issue9
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)1225-1240
P577publication date2017-06-05
P1433published inMolecular OncologyQ2190736
P1476titleHBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis
P478volume11

Reverse relations

cites work (P2860)
Q90362958A Coiled-Coil Domain Containing 50 Splice Variant Is Modulated by Serine/Arginine-Rich Splicing Factor 3 and Promotes Hepatocellular Carcinoma in Mice by the Ras Signaling Pathway
Q59812278Altered epidermal fatty acid-binding protein expression in hepatocellular carcinoma predicts unfavorable outcomes
Q92604695Association between abdominal obesity and liver steatosis and fibrosis among patients with chronic hepatitis B measured by Fibroscan
Q89821133Comparison of clinical features and outcomes between HBV-related and non-B non-C hepatocellular carcinoma
Q64057610Compound L Inhibits HBV-Related HCC through HBx-SHH Pathway Axis Inactivation
Q53830978DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features.
Q55454154Decreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma.
Q40065752Diagnostic value of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage HBV related hepatocellular carcinoma.
Q63975672Diverging inflammasome signals in tumorigenesis and potential targeting
Q90214971Emerging role of lncRNAs in the normal and diseased intestinal barrier
Q89598028Impact of the Interaction of Hepatitis B Virus with Mitochondria and Associated Proteins
Q57492010Inflammasome: A Double-Edged Sword in Liver Diseases
Q64996238Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells.
Q92360836Role of AIM2 inflammasome in inflammatory diseases, cancer and infection
Q46238323The AIM2 inflammasome: Sensor of pathogens and cellular perturbations
Q64289707The HBx-CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1
Q93156405The Multifaceted Roles of Pyroptotic Cell Death Pathways in Cancer

Search more.