Liver cancer in 2013: Mutational landscape of HCC--the end of the beginning.

scientific article published on 07 January 2014

Liver cancer in 2013: Mutational landscape of HCC--the end of the beginning. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NRCLINONC.2013.243
P698PubMed publication ID24395088

P50authorJosep M. LlovetQ37393125
Augusto VillanuevaQ56754203
P2093author name stringAugusto Villanueva
P2860cites workGlobal and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010Q21534928
Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signalingQ33588191
Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosisQ36788468
Focal gains of VEGFA and molecular classification of hepatocellular carcinomaQ36984575
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesionsQ37064910
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinomaQ37138658
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinomaQ37284612
Identification of driver genes in hepatocellular carcinoma by exome sequencingQ37315447
Brivanib versus sorafenib as first-line therapy in patients with unresectable, advanced hepatocellular carcinoma: results from the randomized phase III BRISK-FL studyQ43691230
Brivanib in patients with advanced hepatocellular carcinoma who were intolerant to sorafenib or for whom sorafenib failed: results from the randomized phase III BRISK-PS study.Q45980006
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectliver cancerQ623031
P304page(s)73-74
P577publication date2014-01-07
P1433published inNature Reviews Clinical OncologyQ641640
P1476titleLiver cancer in 2013: Mutational landscape of HCC--the end of the beginning
P478volume11

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cites work (P2860)
Q5536783518β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma.
Q28553513A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells
Q42064611A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma
Q49960144A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma
Q60907348Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming
Q41774349Activated Notch signaling augments cell growth in hepatocellular carcinoma via up-regulating the nuclear receptor NR4A2.
Q38521011Advances in targeted therapies for hepatocellular carcinoma in the genomic era.
Q64104618Association between quantitative parameters of CEUS and Sall4/Wnt/β-catenin signaling in patients with hepatocellular carcinoma
Q33730678Association of hepatitis status with surgical outcomes in patients with dual hepatitis B and C related hepatocellular carcinoma
Q61788093Characterization of Hepatocellular Carcinoma Patients with FGF19 Amplification Assessed by Fluorescence in situ Hybridization: A Large Cohort Study
Q37681728Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways
Q47775953Chemotherapy for hepatocellular carcinoma: current status and future perspectives
Q92340078Circular RNA ABCB10 promotes hepatocellular carcinoma progression by increasing HMG20A expression by sponging miR-670-3p
Q40218092Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options
Q36922232Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.
Q64100196Downregulation of nucleolar and spindle-associated protein 1 expression suppresses liver cancer cell function
Q37317562Dual oncogenic and tumor suppressor roles of the promyelocytic leukemia gene in hepatocarcinogenesis associated with hepatitis B virus surface antigen
Q39366121Emerging tyrosine kinase inhibitors for the treatment of hepatocellular carcinoma
Q55387948Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Q33807832Focal gains of VEGFA: candidate predictors of sorafenib response in hepatocellular carcinoma.
Q28078472Gender Differences in Adipocyte Metabolism and Liver Cancer Progression
Q28073241Genetic alterations in hepatocellular carcinoma: An update
Q37164927HBV is a risk factor for poor patient prognosis after curative resection of hepatocellular carcinoma: A retrospective case-control study
Q38744233HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis
Q90208536HBx/ERα complex-mediated LINC01352 downregulation promotes HBV-related hepatocellular carcinoma via the miR-135b-APC axis
Q56907503Hepatocellular carcinoma
Q39307416Hepatocellular carcinoma treatment: a comparative review of emerging growth factor receptor antagonists
Q64933154Identification of key genes and pathways by bioinformatics analysis with TCGA RNA sequencing data in hepatocellular carcinoma.
Q37610670Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease
Q37580172Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment.
Q31117540Integrative Analysis of Microarray Data to Reveal Regulation Patterns in the Pathogenesis of Hepatocellular Carcinoma
Q36343345Leveraging a Multi-Omics Strategy for Prioritizing Personalized Candidate Mutation-Driver Genes: A Proof-of-Concept Study.
Q35903794Liver cancer: Approaching a personalized care
Q54332985Liver cancer: time to evolve trial design after everolimus failure.
Q36927013Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2.
Q38895324Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis
Q38823802MetastamiRs: A promising choice for antihepatocellular carcinoma nucleic acid drug development
Q41636479Modeling human liver cancer heterogeneity: virally induced transgenic models and mouse genetic models of chronic liver inflammation
Q26745338Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances
Q26766689Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?
Q38282800New molecularly targeted therapies against advanced hepatocellular carcinoma: From molecular pathogenesis to clinical trials and future directions
Q37457920Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing
Q38856299Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents
Q60922492Postoperative adjuvant transarterial chemoembolization for multinodular hepatocellular carcinoma within the Barcelona Clinic Liver Cancer early stage and microvascular invasion
Q37362725Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo
Q55345013Predicting hepatocellular carcinoma development for cirrhosis patients via methylation detection of heparocarcinogenesis-related genes.
Q55035102Predicting hepatocellular carcinoma through cross-talk genes identified by risk pathways.
Q42343451Systemic Chemotherapy for Advanced Hepatocellular Carcinoma: Past, Present, and Future
Q30987443TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways in hepatocellular carcinoma
Q41547180Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells
Q36356419Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib
Q92504694Targeted genomic profiling identifies frequent deleterious mutations in FAT4 and TP53 genes in HBV-associated hepatocellular carcinoma
Q40060996Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma
Q36048511The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling
Q38246712The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets.
Q48287375The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry.
Q47162797The utility of biomarkers in hepatocellular carcinoma: review of urine-based 1H-NMR studies - what the clinician needs to know.
Q41191439Therapeutic strategies for hepatocellular carcinoma: new advances and challenges
Q38259343Tivantinib: critical review with a focus on hepatocellular carcinoma.
Q27853116Unique genomic profile of fibrolamellar hepatocellular carcinoma