Chemotherapy for hepatocellular carcinoma: current status and future perspectives

scientific article published on 15 December 2017

Chemotherapy for hepatocellular carcinoma: current status and future perspectives is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1093/JJCO/HYX180
P698PubMed publication ID29253194

P2093author name stringMasafumi Ikeda
Takuji Okusaka
Hiroshi Ishii
Chigusa Morizane
Junji Furuse
Makoto Ueno
P2860cites workJSH Consensus-Based Clinical Practice Guidelines for the Management of Hepatocellular Carcinoma: 2014 Update by the Liver Cancer Study Group of JapanQ26797521
Treatment of hepatocellular carcinoma with major portal vein thrombosis by combined therapy with subcutaneous interferon-α and intra-arterial 5-fluorouracil; role of type 1 interferon receptor expressionQ27485914
A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.Q42989841
Brivanib versus sorafenib as first-line therapy in patients with unresectable, advanced hepatocellular carcinoma: results from the randomized phase III BRISK-FL studyQ43691230
Brivanib in patients with advanced hepatocellular carcinoma who were intolerant to sorafenib or for whom sorafenib failed: results from the randomized phase III BRISK-PS study.Q45980006
A multi-institutional phase II trial of hepatic arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma with portal vein tumor thrombosisQ46355180
SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma.Q50454368
Hepatic Arterial Infusion Therapy with a Fine Powder Formulation of Cisplatin for Advanced Hepatocellular Carcinoma with Portal Vein Tumor ThrombosisQ53279945
Management of hepatocellular carcinoma: An updateQ27860530
EASL-EORTC clinical practice guidelines: management of hepatocellular carcinomaQ27860783
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Sorafenib in advanced hepatocellular carcinomaQ27861075
Hepatocellular Carcinoma: Therapeutic Guidelines and Medical TreatmentQ28079378
PD-1 Blockade in Tumors with Mismatch-Repair DeficiencyQ28262647
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trialQ29547903
Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung CancerQ29620913
Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: analysis of 48 casesQ33344056
Phase II study of hepatic arterial infusion of a fine-powder formulation of cisplatin for advanced hepatocellular carcinomaQ33379364
Intra-arterial therapy with cisplatin suspension in lipiodol and 5-fluorouracil for hepatocellular carcinoma with portal vein tumour thrombosisQ33389786
Hepatic arterial infusion chemotherapy using low-dose 5-fluorouracil and cisplatin for advanced hepatocellular carcinomaQ33390589
Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized phase III trialQ33410643
Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trialQ33423800
Phase I/II Study of Sorafenib in Combination with Hepatic Arterial Infusion Chemotherapy Using Low-Dose Cisplatin and 5-FluorouracilQ33428936
Effect of everolimus on survival in advanced hepatocellular carcinoma after failure of sorafenib: the EVOLVE-1 randomized clinical trialQ34663499
Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trialQ34786090
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targetsQ36104399
National Cancer Centre Singapore Consensus Guidelines for Hepatocellular Carcinoma.Q37000692
Molecular targeted therapies in hepatocellular carcinomaQ37003665
Development of sorafenib and other molecularly targeted agents in hepatocellular carcinomaQ37015632
Effect of hepatic arterial infusion chemotherapy of 5-fluorouracil and cisplatin for advanced hepatocellular carcinoma in the Nationwide Survey of Primary Liver Cancer in JapanQ37214365
Sorafenib plus hepatic arterial infusion chemotherapy with cisplatin versus sorafenib for advanced hepatocellular carcinoma: randomized phase II trialQ37387978
Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinomaQ37710134
Treatment of advanced hepatocellular carcinoma: intraarterial infusion chemotherapy combined with interferonQ37771190
Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trialQ37809940
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study.Q38062681
Liver cancer in 2013: Mutational landscape of HCC--the end of the beginning.Q38176242
Repetitive short-course hepatic arterial infusion chemotherapy with high-dose 5-fluorouracil and cisplatin in patients with advanced hepatocellular carcinoma.Q38505900
S-1 versus placebo in patients with sorafenib-refractory advanced hepatocellular carcinoma (S-CUBE): a randomised, double-blind, multicentre, phase 3 trialQ38789875
FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinomaQ39297937
Long-term clinical outcomes of hepatic arterial infusion chemotherapy with cisplatin with or without 5-fluorouracil in locally advanced hepatocellular carcinoma.Q39863380
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trialQ40231174
Combination therapy of intraarterial 5-fluorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasionQ40339271
Safety and Pharmacokinetics of Lenvatinib in Patients with Advanced Hepatocellular CarcinomaQ41187204
Systemic Chemotherapy for Advanced Hepatocellular Carcinoma: Past, Present, and FutureQ42343451
Regorafenib as second-line therapy for intermediate or advanced hepatocellular carcinoma: multicentre, open-label, phase II safety studyQ42606277
P921main subjecthepatocellular carcinomaQ1148337
P577publication date2017-12-15
P1433published inJapanese Journal of Clinical OncologyQ2231629
P1476titleChemotherapy for hepatocellular carcinoma: current status and future perspectives

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cites work (P2860)
Q90059424Amyloid precursor protein regulates 5-fluorouracil resistance in human hepatocellular carcinoma cells by inhibiting the mitochondrial apoptotic pathway
Q92701784Antitumor Effect of Pyrogallol via miR-134 Mediated S Phase Arrest and Inhibition of PI3K/AKT/Skp2/cMyc Signaling in Hepatocellular Carcinoma
Q92733290Association of TIM-3 with BCLC Stage, Serum PD-L1 Detection, and Response to Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma
Q92841788Balloon-Occluded Trans-Arterial Chemoembolization Technique with Alternate Infusion of Cisplatin and Gelatin Slurry for Small Hepatocellular Carcinoma Nodules Adjacent to the Glisson Sheath
Q89598588Cyclin-Dependent Kinase and Antioxidant Gene Expression in Cancers with Poor Therapeutic Response
Q97419057Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
Q90450316LncRNA-H19 activates CDC42/PAK1 pathway to promote cell proliferation, migration and invasion by targeting miR-15b in hepatocellular carcinoma
Q64274830Mechanisms of hepatocellular carcinoma progression
Q98946912Obstacles and opportunities in the prevention and treatment of HBV-related hepatocellular carcinoma
Q64232731Peroxiredoxin2 downregulation enhances hepatocellular carcinoma proliferation and migration, and is associated with unfavorable prognosis in patients
Q92625988Pharmacogenetics of the systemic treatment in advanced hepatocellular carcinoma
Q92464147Prognostic significance of inflammatory biomarkers in hepatocellular carcinoma following hepatic resection
Q92643831Role and limitation of neoadjuvant hepatic arterial infusion chemotherapy in advanced hepatocelluar carcinoma patients with Child-Pugh class A
Q90732409Saikosaponin-d Inhibits the Hepatoma Cells and Enhances Chemosensitivity Through SENP5-Dependent Inhibition of Gli1 SUMOylation Under Hypoxia
Q93198729Self-enforcing HMGB1/NF-κB/HIF-1α Feedback Loop Promotes Cisplatin Resistance in Hepatocellular Carcinoma Cells
Q99617219Silencing glioma-associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro
Q57491231Treatment strategies for advanced hepatocellular carcinoma: Sorafenib hepatic arterial infusion chemotherapy
Q93188472Trends in the treatment of advanced hepatocellular carcinoma: immune checkpoint blockade immunotherapy and related combination therapies
Q92285095Ultrasound-Targeted Microbubble Destruction Enhances the Antitumor Efficacy of Doxorubicin in a Mouse Hepatocellular Carcinoma Model
Q92618261miR-101-3p sensitizes hepatocellular carcinoma cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy