Characterization of Hepatocellular Carcinoma Patients with FGF19 Amplification Assessed by Fluorescence in situ Hybridization: A Large Cohort Study

scientific article published on 22 May 2018

Characterization of Hepatocellular Carcinoma Patients with FGF19 Amplification Assessed by Fluorescence in situ Hybridization: A Large Cohort Study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1159/000488541
P932PMC publication ID6388559
P698PubMed publication ID30815392

P50authorSeung-Mo HongQ37392530
Chang Ohk SungQ39689328
Sung-Min AhnQ55136876
Farhan Ul HaqQ59708414
Ju Hyun ShimQ82226483
Jihyun AnQ85583640
P2093author name stringJinho Shin
Jene Choi
Kyu-Pyo Kim
Han Chu Lee
Eunsil Yu
Hyo Jeong Kang
Mi-Ju Kim
Soo-Heang Eo
Hui Jeong Jeong
P2860cites workA mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic miceQ24685118
Clinical impact of copy number variation analysis using high-resolution microarray technologies: advantages, limitations and concernsQ26859057
First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling PathwayQ27698508
Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse modelsQ28729944
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline updateQ33862786
Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinomaQ34151946
Expression of fibroblast growth factor 19 is associated with recurrence and poor prognosis of hepatocellular carcinomaQ34330744
Association of TP53 mutations with stem cell-like gene expression and survival of patients with hepatocellular carcinoma.Q34672668
Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screeningQ34701235
Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the diseaseQ35979451
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targetsQ36104399
FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).Q36983860
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinomaQ37138658
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinomaQ37284612
Genome-wide methylation analysis and epigenetic unmasking identify tumor suppressor genes in hepatocellular carcinoma.Q37481324
Identification of prognostic relevant chromosomal abnormalities in chronic lymphocytic leukemia using microarray-based genomic profilingQ37528942
Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment.Q37580172
Roles of FGF19 in liver metabolism.Q37911126
Liver cancer in 2013: Mutational landscape of HCC--the end of the beginning.Q38176242
New molecular therapies for hepatocellular carcinomaQ38553305
TERT promoter mutations in primary liver tumorsQ38580138
Role of FGF19 induced FGFR4 activation in the regulation of glucose homeostasisQ41974026
Trans-ancestry mutational landscape of hepatocellular carcinoma genomesQ42182370
Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratificationQ42220401
Targeting FGF19/FGFR4 Pathway: A Novel Therapeutic Strategy for Hepatocellular Carcinoma.Q42343453
DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma.Q51499838
Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.Q53331692
P4510describes a project that usesfluorescence in situ hybridizationQ1336182
P433issue1
P304page(s)12-23
P577publication date2018-05-22
P1433published inLiver cancerQ26842090
P1476titleCharacterization of Hepatocellular Carcinoma Patients with FGF19 Amplification Assessed by Fluorescence in situ Hybridization: A Large Cohort Study
P478volume8

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cites work (P2860)
Q92543725FGF19-FGFR4 Signaling in Hepatocellular Carcinoma
Q89911530Serum Fibroblast Growth Factor 19 and Total Bile Acid Concentrations Are Potential Biomarkers of Hepatocellular Carcinoma in Patients with Type 2 Diabetes Mellitus

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