Induction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway

scientific article published on January 2016

Induction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3727/096504016X14634208143021
P8608Fatcat IDrelease_m77fo62zcvd45aig3g6hgheiqi
P932PMC publication ID7838662
P698PubMed publication ID27656831

P50authorHuifang HuangQ91827999
P2093author name stringPing Chen
Xi Jiang
Qin Yuan
Qiang Fu
Qing Jin
Peidong You
P2860cites workInhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTENQ24322051
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
Drug efflux transporters and multidrug resistance in acute leukemia: therapeutic impact and novel approaches to mediationQ26824355
Role of Microenvironment in Resistance to Therapy in AMLQ27027502
Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosisQ28483881
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cellsQ29616552
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formationQ33732463
PI3K-Akt pathway: its functions and alterations in human cancerQ34362034
Activation of the PI3K/Akt pathway and chemotherapeutic resistanceQ35046899
Role of Pten in leukemia stem cellsQ35169570
Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics.Q35841848
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.Q36461618
Loss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastasesQ36694790
The synergistic killing of AML cells co-cultured with HS-5 bone marrow stromal cells by As2O3 and the PI3K/Akt signaling pathway inhibitor LY294002.Q38865334
Bone marrow stromal cells protect acute myeloid leukemia cells from anti-CD44 therapy partly through regulating PI3K/Akt-p27(Kip1) axisQ38939358
Adhesion-Induced Drug Resistance in Leukemia Stem CellsQ39670619
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blastsQ40184405
Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth.Q40195961
Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells.Q40467369
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.Q40526270
The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosisQ40543344
Survival of acute myeloid leukemia cells requires PI3 kinase activationQ44408364
Reduced ABCG2 and increased SLC22A1 mRNA expression are associated with imatinib response in chronic myeloid leukemia.Q46788822
Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: direct evidence of PI3K activationQ47399980
Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local recurrence?Q51704738
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.Q53520724
[Regulatory mechanisms of PI3K/AKT signaling pathway in acute leukemia].Q54525477
Stromal niche cells protect early leukemic FLT3-ITD+ progenitor cells against first-generation FLT3 tyrosine kinase inhibitors.Q54592057
[Study of the mutation and expression of PTEN gene in endometrial carcinoma and epithelial ovarian cancer]Q78679085
Expression of three different ATP-binding cassette transporters and correlation to chemoresistance in acute myeloid leukemiaQ87835728
P433issue4
P921main subjectacute myeloid leukemiaQ264118
multiple drug resistanceQ643839
P304page(s)215-223
P577publication date2016-01-01
P1433published inOncology ResearchQ15750114
P1476titleInduction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway
P478volume24

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cites work (P2860)
Q49882954Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression
Q64108876Mechanisms of drug resistance in acute myeloid leukemia

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