Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage.

scientific article published on 17 August 2016

Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1012267985
P356DOI10.1007/S00280-016-3110-Y
P698PubMed publication ID27535835

P50authorWoo-Yoon ParkQ73706620
P2093author name stringJae-Ran Yu
Zhengzhe An
Prabakaran D Subramanian
P2860cites workRegulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/AktQ24306562
An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complexQ24313607
EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatmentQ24338426
Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatinQ33200727
Epidermal growth factor receptor signaling in colorectal cancer: preclinical data and therapeutic perspectivesQ33211152
Ft1, a novel gene related to ubiquitin-conjugating enzymes, is deleted in the Fused toes mouse mutationQ34447767
Phase II study of cisplatin plus cetuximab in advanced, recurrent, and previously treated cancers of the cervix and evaluation of epidermal growth factor receptor immunohistochemical expression: a Gynecologic Oncology Group studyQ34850394
Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: a Gynecologic Oncology Group studyQ35154219
A phase II trial of erlotinib in recurrent squamous cell carcinoma of the cervix: a Gynecologic Oncology Group StudyQ37294922
Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinomaQ37316834
Nuclear EGFR as novel therapeutic target: insights into nuclear translocation and functionQ37676970
Cisplatin resistance: preclinical findings and clinical implicationsQ37774468
Prognostic cell biological markers in cervical cancer patients primarily treated with (chemo)radiation: a systematic reviewQ37825064
Epidermal growth factor receptor as a biomarker for cervical cancerQ37843137
EGFR inhibitor enhances cisplatin sensitivity of oral squamous cell carcinoma cell linesQ38847029
FTS is responsible for radiation-induced nuclear phosphorylation of EGFR and repair of DNA damage in cervical cancer cells.Q38963347
EGF-induced expression of Fused Toes Homolog (FTS) facilitates epithelial-mesenchymal transition and promotes cell migration in ME180 cervical cancer cellsQ39284745
Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistanceQ39290667
Fused Toes Homolog modulates radiation cytotoxicity in uterine cervical cancer cells.Q39572618
FTS (fused toes homolog) a novel oncoprotein involved in uterine cervical carcinogenesis and a potential diagnostic marker for cervical cancerQ39644388
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activityQ40396981
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinaseQ40401323
Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines.Q40451017
Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cellsQ40554483
DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatinQ40680519
Cisplatin-induced activation of the EGF receptorQ42807345
cIAP2 Upregulated by E6 Oncoprotein via Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/AKT Pathway Confers Resistance to Cisplatin in Human Papillomavirus 16/18–Infected Lung CancerQ43777713
EGCG suppresses Fused Toes Homolog protein through p53 in cervical cancer cells.Q50472183
P433issue4
P304page(s)753-762
P577publication date2016-08-17
P1433published inCancer Chemotherapy and PharmacologyQ326137
P1476titleSilencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage
P478volume78

Search more.