Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells.

scientific article published on 8 August 2016

Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1158/0008-5472.CAN-16-0800
P932PMC publication ID5065765
P698PubMed publication ID27503927

P50authorVladimir L. GabaiQ54877934
P2093author name stringMichael Y Sherman
Hao Shao
Yongmei Wang
Teresa Colvin
Le Meng
Geunwon Kim
Jason Gestwicki
Julia A Yaglom
P2860cites workMacrophages and cancer: from mechanisms to therapeutic implicationsQ38377725
Eco-evolution of cancer resistanceQ38749215
Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancerQ38922557
Tumor-derived inducible heat-shock protein 70 (HSP70) is an essential component of anti-tumor immunityQ39012311
BAG3 regulates motility and adhesion of epithelial cancer cells.Q40059282
Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasisQ42171605
Foxm1 transcription factor is required for macrophage migration during lung inflammation and tumor formationQ42591775
Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategyQ43166847
Impaired tumor growth in colony-stimulating factor 1 (CSF-1)-deficient, macrophage-deficient op/op mouse: evidence for a role of CSF-1-dependent macrophages in formation of tumor stromaQ70842368
High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathwaysQ79856384
HSP72 depletion suppresses gammaH2AX activation by genotoxic stresses via p53/p21 signalingQ82452820
Tumor-associated macrophages promote angiogenesis and melanoma growth via adrenomedullin in a paracrine and autocrine mannerQ85085662
Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesQ26782778
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapyQ27690653
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progressionQ29614274
Macrophage diversity enhances tumor progression and metastasisQ29615847
Hsp70-Bag3 interactions regulate cancer-related signaling networksQ30009385
Tumor progression locus 2 (Tpl2) kinase promotes chemokine receptor expression and macrophage migration during acute inflammationQ34076041
Heat shock proteins in cancer: chaperones of tumorigenesisQ34495261
The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancyQ34599918
Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesisQ36208512
Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.Q37033622
Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancerQ37395883
Hallmarks of cancer: interactions with the tumor stroma.Q37704659
Hsp70 in cancer: back to the futureQ38263003
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)5926-5932
P577publication date2016-08-08
P1433published inCancer ResearchQ326097
P1476titleAnticancer Effects of Targeting Hsp70 in Tumor Stromal Cells
P478volume76

Reverse relations

cites work (P2860)
Q39329712"Heat shock protein 70 in pancreatic diseases: Friend or foe".
Q50354200Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations.
Q98158658Cancer-associated fibroblasts stimulate primary tumor growth and metastatic spread in an orthotopic prostate cancer xenograft model
Q89219409Enzyme-treated Asparagus Extract Down-regulates Heat Shock Protein 27 of Pancreatic Cancer Cells
Q99414066Exhaustion of Protective Heat Shock Response Induces Significant Tumor Damage by Apoptosis after Modulated Electro-Hyperthermia Treatment of Triple Negative Breast Cancer Isografts in Mice
Q89313592Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70)
Q90080306Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond
Q64941692Hsp70 (HSP70A1A) downregulation enhances the metastatic ability of cancer cells.
Q90058197Individualized management of genetic diversity in Niemann-Pick C1 through modulation of the Hsp70 chaperone system
Q90350600Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding
Q91239720The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20

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