Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression

scientific article published on 14 June 2016

Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2016.06.001
P932PMC publication ID4969160
P698PubMed publication ID27314620

P50authorEdward C. HolmesQ28152069
P2093author name stringMiao Sun
Colin R Parrish
Kurtis H Feng
Sho Iketani
P2860cites workIntroduction to NF-kappaB: players, pathways, perspectivesQ28271022
Influenza a virus host shutoff disables antiviral stress-induced translation arrestQ28540648
E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3Q28547141
The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses.Q30371441
Influenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune ResponsesQ30373511
Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity.Q30373730
PA-X is a virulence factor in avian H9N2 influenza virus.Q30378192
TNF and MAP kinase signalling pathwaysQ33905516
Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion stepQ34120198
Transport of influenza virus neuraminidase (NA) to host cell surface is regulated by ARHGAP21 and Cdc42 proteinsQ34253111
Influenza virus assembly and buddingQ34913111
Influenza virus induction of apoptosis by intrinsic and extrinsic mechanismsQ35213616
PA-X decreases the pathogenicity of highly pathogenic H5N1 influenza A virus in avian species by inhibiting virus replication and host responseQ35640905
TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 PolymeraseQ35658224
Equine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic DivergenceQ35745427
Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein.Q35915706
Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza A virusQ36363892
An overlapping protein-coding region in influenza A virus segment 3 modulates the host responseQ36554219
Truncation of C-terminal 20 amino acids in PA-X contributes to adaptation of swine influenza virus in pigsQ36615704
Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis.Q36668024
Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein ClusterinQ36738106
Interplay between viruses and host mRNA degradationQ36785197
Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapyQ37247082
Transport of the influenza virus genome from nucleus to nucleusQ37271683
The D10 decapping enzyme of vaccinia virus contributes to decay of cellular and viral mRNAs and to virulence in miceQ37547637
Association of influenza virus proteins with membrane rafts.Q37982058
Apoptosis signaling in influenza virus propagation, innate host defense, and lung injuryQ37985804
Molecular mechanisms enhancing the proteome of influenza A viruses: an overview of recently discovered proteins.Q38199917
Timing Is Everything: Coordinated Control of Host Shutoff by Influenza A Virus NS1 and PA-X ProteinsQ38422972
The nucleoprotein of influenza A virus induces p53 signaling and apoptosis via attenuation of host ubiquitin ligase RNF43.Q38872665
Influenza A virus hemagglutinin and neuraminidase mutually accelerate their apical targeting through clustering of lipid raftsQ38981236
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferonQ39593618
Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B.Q39869036
NF-kappaB signaling differentially regulates influenza virus RNA synthesisQ39950905
Active NF-kappaB signalling is a prerequisite for influenza virus infection.Q40532649
Mapping of a Region of the PA-X Protein of Influenza A Virus That Is Important for Its Shutoff Activity.Q40871573
The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA.Q41347441
TRIM proteins and cancer.Q53280723
P407language of work or nameEnglishQ1860
P921main subjectcanine influenzaQ2040895
RNA sequencingQ2542347
P304page(s)138-146
P577publication date2016-06-14
P1433published inVirologyQ7934867
P1476titleComparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression
P478volume496

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cites work (P2860)
Q56970558A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies
Q57093666Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in Humans
Q58762417Host Shutoff in Influenza A Virus: Many Means to an End
Q40150668Interplay of PA-X and NS1 Proteins in Replication and Pathogenesis of a Temperature-Sensitive 2009 Pandemic H1N1 Influenza A Virus
Q56563872PA-X: a key regulator of influenza A virus pathogenicity and host immune responses
Q90244937R195K mutation in the PA-X protein increases the virulence and transmission of influenza A virus in mammalian hosts
Q40072930The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression.

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