| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1085444184 |
| P356 | DOI | 10.1007/S00401-017-1722-X |
| P698 | PubMed publication ID | 28527044 |
| P50 | author | Jeffrey H Kordower | Q67168846 |
| Ronald Melki | Q30123639 | ||
| P2093 | author name string | Edward M Campbell | |
| Luc Bousset | |||
| Yaping Chu | |||
| Michael J Chaney | |||
| Stratos Skarpathiotis | |||
| William P Flavin | |||
| Zachary C Green | |||
| P2860 | cites work | Tracking the dynamic interplay between bacterial and host factors during pathogen-induced vacuole rupture in real time | Q48827027 |
| Lysosomal membrane permeabilization in Parkinson disease | Q57245740 | ||
| Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion | Q24301905 | ||
| Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies | Q24307627 | ||
| α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells | Q24633663 | ||
| Transmission and spreading of tauopathy in transgenic mouse brain | Q24651334 | ||
| Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein | Q24655848 | ||
| Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates | Q24657543 | ||
| Self-propagation of pathogenic protein aggregates in neurodegenerative diseases | Q26996441 | ||
| Autophagy in the regulation of pathogen replication and adaptive immunity | Q27023949 | ||
| Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis | Q27323098 | ||
| Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
| Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host | Q28264821 | ||
| Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease | Q28275257 | ||
| The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia | Q29547174 | ||
| AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease | Q29547175 | ||
| Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation | Q29615640 | ||
| Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice | Q29620597 | ||
| VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy | Q30274624 | ||
| Spatiotemporal dynamics of adenovirus membrane rupture and endosomal escape | Q30525259 | ||
| Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury | Q30544606 | ||
| Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. | Q34043163 | ||
| G51D α‐synuclein mutation causes a novel Parkinsonian–pyramidal syndrome | Q34335126 | ||
| Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles | Q34869120 | ||
| Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice | Q34909750 | ||
| Molecular interaction between the chaperone Hsc70 and the N-terminal flank of huntingtin exon 1 modulates aggregation | Q35048841 | ||
| Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates. | Q35215169 | ||
| Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death | Q35484581 | ||
| Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis | Q35601755 | ||
| Lewy-body formation is an aggresome-related process: a hypothesis | Q35840040 | ||
| Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice | Q35946149 | ||
| Fibrillar α-Synuclein and Huntingtin Exon 1 Assemblies Are Toxic to the Cells | Q36045483 | ||
| Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. | Q36066469 | ||
| Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions | Q36079533 | ||
| Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay. | Q36111729 | ||
| α-synuclein assemblies sequester neuronal α3-Na+/K+-ATPase and impair Na+ gradient | Q36148374 | ||
| α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models | Q36607556 | ||
| Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy | Q36617500 | ||
| Prion-like spreading of pathological α-synuclein in brain | Q36732844 | ||
| Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization | Q36744478 | ||
| Structural and functional properties of prefibrillar α-synuclein oligomers | Q36796130 | ||
| Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy | Q36873680 | ||
| Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein. | Q36907208 | ||
| Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification | Q36960882 | ||
| The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease | Q37054679 | ||
| Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. | Q37110592 | ||
| Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson's disease | Q37197984 | ||
| Structural and functional characterization of two alpha-synuclein strains | Q37305236 | ||
| Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein | Q37453948 | ||
| Lysosomal impairment in Parkinson's disease | Q37461364 | ||
| A deadly spread: cellular mechanisms of α-synuclein transfer | Q37874930 | ||
| Lysosome-dependent pathways as a unifying theme in Parkinson's disease. | Q38038561 | ||
| Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases | Q38185934 | ||
| What lysosomes actually tell us about Parkinson's disease? | Q38762469 | ||
| Cellular response of human neuroblastoma cells to α-synuclein fibrils, the main constituent of Lewy bodies | Q38827784 | ||
| Binding, internalization and fate of Huntingtin Exon1 fibrillar assemblies in mitotic and nonmitotic neuroblastoma cells | Q38860098 | ||
| Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. | Q39595928 | ||
| Galectin-3, a marker for vacuole lysis by invasive pathogens. | Q39768742 | ||
| Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein. | Q40010392 | ||
| Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death | Q40405034 | ||
| α-Synuclein strains cause distinct synucleinopathies after local and systemic administration | Q41681113 | ||
| TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis | Q41863769 | ||
| Distinct tau prion strains propagate in cells and mice and define different tauopathies | Q41904960 | ||
| Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau | Q41979763 | ||
| Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes | Q42388077 | ||
| Cell-to-Cell Transmission of α-Synuclein Aggregates | Q42426303 | ||
| Role of galectin-3 in prion infections of the CNS. | Q44545489 | ||
| PA700, the regulatory complex of the 26S proteasome, interferes with alpha-synuclein assembly | Q46648354 | ||
| Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions | Q48581414 | ||
| P921 | main subject | cellular invasion | Q130614649 |
| P577 | publication date | 2017-05-19 | |
| P1433 | published in | Acta Neuropathologica | Q343168 |
| P1476 | title | Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins |
| Q57298268 | 2D polarization imaging as a low-cost fluorescence method to detect α-synuclein aggregation ex vivo in models of Parkinson's disease |
| Q58596800 | Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells |
| Q92049502 | C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease |
| Q102220321 | CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects |
| Q61797575 | Clustering of Tau fibrils impairs the synaptic composition of α3-Na/K-ATPase and AMPA receptors |
| Q47619917 | Critical appraisal of pathology transmission in the α-synuclein fibril model of Lewy body disorders. |
| Q89720828 | Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs |
| Q41378022 | Following the fate of endocytosed fibrils |
| Q98177882 | Galectin-3 Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Reduces Aberrant Tau Phosphorylation in an Alzheimer Disease Model |
| Q92377188 | Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease |
| Q47251029 | Galectin-8-mediated selective autophagy protects against seeded tau aggregation |
| Q38631574 | Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates |
| Q55339738 | Import and Export of Misfolded α-Synuclein. |
| Q91474636 | Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity |
| Q48103278 | Intracellular tracing of amyloid vaccines through direct fluorescent labelling |
| Q91862920 | K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α |
| Q64966531 | LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. |
| Q92104903 | Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson's Disease |
| Q54988763 | Microglial Lectins in Health and Neurological Diseases. |
| Q95940310 | Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses |
| Q64867396 | Prion-like propagation of pathology in Parkinson disease |
| Q64238991 | Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network |
| Q90591155 | Protein transmission in neurodegenerative disease |
| Q92063917 | Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress |
| Q92235387 | Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading |
| Q64115757 | Repeat domain-associated O-glycans govern PMEL fibrillar sheet architecture |
| Q94686336 | Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins |
| Q41378010 | Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies. |
| Q64968356 | The Role of Antibodies and Their Receptors in Protection Against Ordered Protein Assembly in Neurodegeneration. |
| Q53841253 | The concept of alpha-synuclein as a prion-like protein: ten years after |
| Q90408376 | The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding |
| Q57838382 | Transcellular Spreading of Tau in Tauopathies |
| Q47844521 | Transcriptional Effects of ApoE4: Relevance to Alzheimer's Disease |
| Q59137099 | Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action |
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