Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury

scientific article published on 06 April 2016

Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1022972900
P356DOI10.1007/S00204-016-1693-Z
P698PubMed publication ID27052460

P50authorSifeng ChenQ57015502
Joe YeongQ57368883
P2093author name stringLiang Chen
Xiaoming Yang
Xiaobo Li
Xinhong Wang
Lianhua Yin
Yanxia Ning
Zhengyang Wang
Xiuling Zhi
Hanyu Lu
P2860cites workGender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 productionQ29614596
Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinomaQ34035095
Foxl1 is a marker of bipotential hepatic progenitor cells in miceQ34099496
Activation of stem cells in hepatic diseases.Q34554113
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivoQ34674259
Age- and sex-dependent expression of multiple murine hepatic hydroxysteroid sulfotransferase (SULT2A) genesQ34905708
Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in miceQ35002110
Liver regeneration and repair: hepatocytes, progenitor cells, and stem cellsQ35797586
Adult hepatocytes are generated by self-duplication rather than stem cell differentiation.Q35861861
Hepatic oval cells: helping redefine a paradigm in stem cell biologyQ35879286
Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro.Q36175918
The origin, biology, and therapeutic potential of facultative adult hepatic progenitor cellsQ36450461
LXR signaling couples sterol metabolism to proliferation in the acquired immune response.Q37061238
Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytesQ37308118
Inflammation and lipid signaling in the etiology of insulin resistanceQ38007632
Oxysterol receptors, AKT and prostate cancer.Q38028127
Oxysterols in cancer cell proliferation and deathQ38090330
SULT2B1: unique properties and characteristics of a hydroxysteroid sulfotransferase familyQ38135858
STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.Q38358871
Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regenerationQ38359037
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathwayQ38926285
Suppression of beta-catenin signaling by liver X receptor ligandsQ39921452
Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferationQ40178562
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.Q40190327
Differential lymphotoxin-beta and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury.Q40468715
Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytesQ43203668
Enzyme activity assay for cholesterol 27-hydroxylase in mitochondriaQ44918704
A nuclear strike against Listeria--the evolving life of LXR.Q45103209
TNF/LTalpha double knockout mice display abnormal inflammatory and regenerative responses to acute and chronic liver injuryQ45183801
Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophagesQ46084106
Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells.Q46913797
Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liverQ47835382
Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.Q48622349
Hepatic loss of survivin impairs postnatal liver development and promotes expansion of hepatic progenitor cells in mice.Q50867667
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.Q52522262
Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.Q52580893
Mitosis and apoptosis in the liver of interleukin-6-deficient mice after partial hepatectomyQ57272886
P433issue1
P921main subjecthydroxysteroidQ2157080
RNA sequencingQ2542347
P304page(s)271-287
P577publication date2016-04-06
P1433published inArchives of ToxicologyQ635837
P1476titleUpregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury
P478volume91

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cites work (P2860)
Q91329598HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression
Q39336170Implications of sulfotransferase activity in interindividual variability in drug response: clinical perspective on current knowledge.
Q41396483Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice
Q90171107Protein tyrosine phosphatase L1 represses endothelial-mesenchymal transition by inhibiting IL-1β/NF-κB/Snail signaling

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