review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Katherine A Abrahams | Q52125562 |
P2093 | author name string | Gurdyal S Besra | |
P2860 | cites work | targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis | Q21202793 |
The Galactosamine Residue in Mycobacterial Arabinogalactan Is α-Linked | Q63360963 | ||
Acylation State of the Phosphatidylinositol Mannosides fromMycobacterium bovisBacillus Calmette Guérin and Ability to Induce Granuloma and Recruit Natural Killer T Cells | Q63361575 | ||
Galactose-derived phosphonate analogues as potential inhibitors of phosphatidylinositol biosynthesis in mycobacteria | Q63363181 | ||
Predominant structural features of the cell wall arabinogalactan of Mycobacterium tuberculosis as revealed through characterization of oligoglycosyl alditol fragments by gas chromatography/mass spectrometry and by 1H and 13C NMR analyses | Q67283043 | ||
Location of the mycolyl ester substituents in the cell walls of mycobacteria | Q67992902 | ||
Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls | Q68556386 | ||
Demonstration that the galactosyl and arabinosyl residues in the cell-wall arabinogalactan of Mycobacterium leprae and Mycobacterium tuberculosis are furanoid | Q70366212 | ||
Amphomycin: effect of the lipopeptide antibiotic on the glycosylation and extraction of dolichyl monophosphate in calf brain membranes | Q70754020 | ||
A new interpretation of the structure of the mycolyl-arabinogalactan complex of Mycobacterium tuberculosis as revealed through characterization of oligoglycosylalditol fragments by fast-atom bombardment mass spectrometry and 1H nuclear magnetic reso | Q72125562 | ||
Recognition of the lipid intermediate for arabinogalactan/arabinomannan biosynthesis and its relation to the mode of action of ethambutol on mycobacteria | Q72181562 | ||
TREATMENT of pulmonary tuberculosis with isoniazid; an interim report to the Medical Research Council by their Tuberculosis Chemotherapy Trials Committee | Q73953257 | ||
THE STRUCTURE OF A MYOINOSITOL MANNOSIDE FROM MYCOBACTERIUM TUBERCULOSIS GLYCOLIPID | Q76915146 | ||
Structural studies on the myo-inositol phospholipids of Mycobacterium tuberculosis (var. bovis, strain BCG) | Q79572464 | ||
5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases | Q58216000 | ||
Characterization of a putative α-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis | Q58286606 | ||
Crystal Structure of a Novel β-Lactam-insensitive Peptidoglycan Transpeptidase | Q58346927 | ||
ESI-MS Assay of M. tuberculosis Cell Wall Antigen 85 Enzymes Permits Substrate Profiling and Design of a Mechanism-Based Inhibitor | Q60914231 | ||
The Carboxy Terminus of EmbC fromMycobacterium smegmatisMediates Chain Length Extension of the Arabinan in Lipoarabinomannan | Q62736137 | ||
Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme | Q34269294 | ||
Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme | Q34286689 | ||
Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent | Q34300761 | ||
Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug | Q34383718 | ||
Structure-activity relationships at the 5-position of thiolactomycin: an intact (5R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli | Q34619663 | ||
Structure, biochemistry and mechanism of action of glycopeptide antibiotics | Q34665729 | ||
Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response | Q34727406 | ||
Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli | Q34843809 | ||
Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching | Q35069666 | ||
A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms | Q35122617 | ||
Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors | Q35243846 | ||
Direct inhibitors of InhA are active against Mycobacterium tuberculosis. | Q35247307 | ||
Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone | Q35461578 | ||
Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis. | Q35546031 | ||
Lead selection and characterization of antitubercular compounds using the Nested Chemical Library | Q35584789 | ||
Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species | Q35601166 | ||
Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection | Q35860128 | ||
Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis | Q35867371 | ||
SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis | Q35867500 | ||
Identification of the apparent carrier in mycolic acid synthesis | Q36000971 | ||
Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis | Q36037140 | ||
Fluorescence-based assay for polyprenyl phosphate-GlcNAc-1-phosphate transferase (WecA) and identification of novel antimycobacterial WecA inhibitors | Q36105224 | ||
The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis | Q36150070 | ||
Inactivation of Mycobacterium tuberculosis l,d-transpeptidase LdtMt₁ by carbapenems and cephalosporins | Q36171768 | ||
Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis | Q36310020 | ||
MraY Inhibitors as Novel Antibacterial Agents | Q36321142 | ||
Molecular docking studies on InhA, MabA and PanK enzymes from Mycobacterium tuberculosis of ellagic acid derivatives from Ludwigia adscendens and Trewia nudiflora. | Q36352683 | ||
In vitro antimycobacterial activities of capuramycin analogues | Q36424956 | ||
Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening. | Q36575914 | ||
Critical roles for lipomannan and lipoarabinomannan in cell wall integrity of mycobacteria and pathogenesis of tuberculosis | Q36613333 | ||
The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates | Q36721545 | ||
Identification of a novel alpha(1-->6) mannopyranosyltransferase MptB from Corynebacterium glutamicum by deletion of a conserved gene, NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant. | Q36737388 | ||
Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis. Inhibition of arabinan biosynthesis by ethambutol | Q36831508 | ||
Mutations in pimE restore lipoarabinomannan synthesis and growth in a Mycobacterium smegmatis lpqW mutant | Q28486481 | ||
Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria | Q28486491 | ||
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis | Q28486505 | ||
Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis | Q28486563 | ||
MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II | Q28486575 | ||
The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis | Q28486719 | ||
Antigen 85C-mediated acyl-transfer between synthetic acyl donors and fragments of the arabinan | Q28486729 | ||
Identification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis | Q28486750 | ||
Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose | Q28486790 | ||
Mycobacterium tuberculosis Rv1302 and Mycobacterium smegmatis MSMEG_4947 have WecA function and MSMEG_4947 is required for the growth of M. smegmatis | Q28486792 | ||
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis | Q28486804 | ||
The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid | Q28486806 | ||
Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis | Q28486808 | ||
Expression, purification, and characterization of a galactofuranosyltransferase involved in Mycobacterium tuberculosis arabinogalactan biosynthesis | Q28486851 | ||
Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope | Q28486853 | ||
Identification and substrate specificity of beta -ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis | Q28486928 | ||
Mycobacterium tuberculosis phoP mutant: lipoarabinomannan molecular structure | Q28487144 | ||
Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase | Q28487197 | ||
Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB | Q28487213 | ||
A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis | Q28487225 | ||
Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides | Q28487273 | ||
Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane | Q28487303 | ||
Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis | Q28487338 | ||
Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae | Q28487429 | ||
Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase | Q28487466 | ||
Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis | Q28487484 | ||
Redundant function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis cyclopropanation of oxygenated mycolates | Q28487498 | ||
Inactivation of the mycobacterial rhamnosyltransferase, which is needed for the formation of the arabinogalactan-peptidoglycan linker, leads to irreversible loss of viability | Q28487566 | ||
Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis | Q28487576 | ||
Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria | Q28487603 | ||
Lipoarabinomannan of Mycobacterium: mannose capping by a multifunctional terminal mannosyltransferase | Q28487622 | ||
Characterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosis | Q28488668 | ||
New insights into the early steps of phosphatidylinositol mannoside biosynthesis in mycobacteria: PimB' is an essential enzyme of Mycobacterium smegmatis | Q28501847 | ||
Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases | Q21562402 | ||
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence | Q22122411 | ||
The Envelope of Mycobacteria | Q22241995 | ||
Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture | Q24535935 | ||
Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors | Q24614299 | ||
Galactosyl transferases in mycobacterial cell wall synthesis | Q24641902 | ||
Development of a microtitre plate-based assay for lipid-linked glycosyltransferase products using the mycobacterial cell wall rhamnosyltransferase WbbL | Q24642902 | ||
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase | Q24656511 | ||
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall | Q24678269 | ||
Lipid Flippases for Bacterial Peptidoglycan Biosynthesis | Q26770493 | ||
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria | Q27644814 | ||
Structure and function of GlmU fromMycobacterium tuberculosis | Q27653924 | ||
Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis | Q27653976 | ||
Structure of the Mycobacterium tuberculosis d -Alanine: d -Alanine Ligase, a Target of the Antituberculosis Drug d -Cycloserine | Q27665159 | ||
The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module | Q27667217 | ||
Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors | Q27681391 | ||
Towards a new combination therapy for tuberculosis with next generation benzothiazinones | Q27681604 | ||
Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA | Q27688958 | ||
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria | Q27727961 | ||
The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism. | Q27936943 | ||
Kinetic mechanism and inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by the antibiotic D-cycloserine | Q28282522 | ||
Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis | Q28302775 | ||
The Mycobacterium tuberculosis FAS-II condensing enzymes: their role in mycolic acid biosynthesis, acid-fastness, pathogenesis and in future drug development | Q28305447 | ||
Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis | Q28375163 | ||
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors | Q28471626 | ||
Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria | Q28471837 | ||
Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteria | Q28484652 | ||
Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB | Q28484670 | ||
Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 | Q28486239 | ||
Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II | Q28486328 | ||
The peptidoglycan of stationary-phase Mycobacterium tuberculosis predominantly contains cross-links generated by L,D-transpeptidation | Q28486366 | ||
Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis | Q28486429 | ||
PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria | Q28501849 | ||
Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species | Q28501856 | ||
A Mycobacterium smegmatis mutant with a defective inositol monophosphate phosphatase gene homolog has altered cell envelope permeability | Q28501859 | ||
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis | Q28533721 | ||
Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation | Q28544916 | ||
Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target | Q28545065 | ||
Identification of KasA as the cellular target of an anti-tubercular scaffold | Q28830072 | ||
inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis | Q29617412 | ||
Peptidoglycan structure and architecture | Q29617858 | ||
Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action | Q30419537 | ||
Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32 | Q30432374 | ||
Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity | Q31473388 | ||
Structural analysis of mycobacterial lipoglycans | Q33205731 | ||
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core | Q33220238 | ||
Pharmacoproteomic effects of isoniazid, ethambutol, and N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine (SQ109) on Mycobacterium tuberculosis H37Rv | Q33221264 | ||
Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosis | Q33243649 | ||
Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis | Q33244525 | ||
The identification and location of succinyl residues and the characterization of the interior arabinan region allow for a model of the complete primary structure of Mycobacterium tuberculosis mycolyl arabinogalactan | Q33321365 | ||
Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones | Q33370732 | ||
The mycolyltransferase 85A, a putative drug target of Mycobacterium tuberculosis: development of a novel assay and quantification of glycolipid-status of the mycobacterial cell wall | Q33512644 | ||
Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics | Q33540441 | ||
Specificity of the transport of lipid II by FtsW in Escherichia coli | Q33652106 | ||
A truncated lipoglycan from mycobacteria with altered immunological properties | Q33664341 | ||
N Glycolylation of the nucleotide precursors of peptidoglycan biosynthesis of Mycobacterium spp. is altered by drug treatment | Q33716658 | ||
Mycobacterial lipid II is composed of a complex mixture of modified muramyl and peptide moieties linked to decaprenyl phosphate | Q33726863 | ||
Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions. | Q33917913 | ||
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 | Q34056972 | ||
Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane | Q34169371 | ||
Bacterial cell wall. MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis. | Q34175962 | ||
Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor | Q37034701 | ||
Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis | Q37038925 | ||
Cytoplasmic steps of peptidoglycan biosynthesis | Q37081699 | ||
The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis | Q37081708 | ||
Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis. | Q37168695 | ||
Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45 | Q37234023 | ||
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis | Q37247725 | ||
AftD, a novel essential arabinofuranosyltransferase from mycobacteria | Q37376674 | ||
Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis | Q37519148 | ||
Indoleamides are active against drug-resistant Mycobacterium tuberculosis | Q37541307 | ||
Recent progress in the identification and development of InhA direct inhibitors of Mycobacterium tuberculosis | Q37735233 | ||
Targeting InhA, the FASII enoyl-ACP reductase: SAR studies on novel inhibitor scaffolds. | Q37979307 | ||
Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F. | Q38206339 | ||
Binding of the terminal mannosyl units of lipoarabinomannan from a virulent strain of Mycobacterium tuberculosis to human macrophages. | Q38309145 | ||
UDP-GlcNAc pathway: Potential target for inhibitor discovery against M. tuberculosis | Q38675255 | ||
Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants | Q39024963 | ||
Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis. | Q39804087 | ||
Molecular mechanisms of isoniazid resistance in Mycobacterium tuberculosis and Mycobacterium bovis. | Q39821736 | ||
GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis | Q40540582 | ||
Molecular genetics of drug resistance in Mycobacterium tuberculosis | Q40575592 | ||
Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity | Q40679059 | ||
The role of the embA and embB gene products in the biosynthesis of the terminal hexaarabinofuranosyl motif of Mycobacterium smegmatis arabinogalactan. | Q40679743 | ||
Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice | Q40875190 | ||
Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis | Q41594961 | ||
Galactosamine in walls of slow-growing mycobacteria | Q41836041 | ||
Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster | Q41969973 | ||
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis | Q42111035 | ||
Mannose metabolism is required for mycobacterial growth | Q42113994 | ||
MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria | Q42189366 | ||
Novel prenyl-linked benzophenone substrate analogues of mycobacterial mannosyltransferases. | Q42253910 | ||
Design and synthesis of novel cell wall inhibitors of Mycobacterium tuberculosis GlmM and GlmU. | Q42731628 | ||
Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis | Q43001474 | ||
Epimeric and amino disaccharide analogs as probes of an alpha-(1-->6)-mannosyltransferase involved in mycobacterial lipoarabinomannan biosynthesis | Q43213868 | ||
Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis | Q43544331 | ||
Synthetic mannosides act as acceptors for mycobacterial alpha1-6 mannosyltransferase | Q43608969 | ||
Separation and characterization of individual mycolic acids in representative mycobacteria | Q43655749 | ||
Synthesis of disaccharides related to the mycobacterial arabinogalactan | Q43707816 | ||
Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural principles in mycolic acids | Q44021566 | ||
Synthesis and evaluation of galactofuranosyl N,N-dialkyl sulfenamides and sulfonamides as antimycobacterial agents. | Q44196146 | ||
Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis | Q44198145 | ||
The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan | Q44258976 | ||
Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques | Q44324006 | ||
Mycolic acid structure determines the fluidity of the mycobacterial cell wall | Q44732618 | ||
Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall | Q44921136 | ||
Triclosan as a substrate and inhibitor of 3'-phosphoadenosine 5'-phosphosulfate-sulfotransferase and UDP-glucuronosyl transferase in human liver fractions | Q44989650 | ||
Identification of the 5-methylthiopentosyl substituent in Mycobacterium tuberculosis lipoarabinomannan | Q44993198 | ||
Activity of capuramycin analogues against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium intracellulare in vitro and in vivo | Q45044140 | ||
Synthesis of methyl 5-S-alkyl-5-thio-D-arabinofuranosides and evaluation of their antimycobacterial activity | Q45059460 | ||
Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycan | Q45136861 | ||
Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors | Q46256266 | ||
Simultaneous estimation of pharmacokinetic properties in mice of three anti-tubercular ethambutol analogs obtained from combinatorial lead optimization. | Q46410603 | ||
A novel peptidoglycan cross-linking enzyme for a beta-lactam-resistant transpeptidation pathway | Q46689287 | ||
Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis | Q46726125 | ||
Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase | Q49049841 | ||
The effect of MSMEG_6402 gene disruption on the cell wall structure of Mycobacterium smegmatis. | Q52611102 | ||
Effects of moenomycin on Escherichia coli. | Q54411026 | ||
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. | Q54590227 | ||
Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU). | Q54698121 | ||
Identification of a Novel Arabinofuranosyltransferase AftB Involved in a Terminal Step of Cell Wall Arabinan Biosynthesis in Corynebacterianeae, such asCorynebacterium glutamicumandMycobacterium tuberculosis | Q58040456 | ||
Biosynthesis of Mycobacterial Lipoarabinomannan | Q58040726 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P921 | main subject | cell wall | Q128700 |
cell | Q7868 | ||
bacteria | Q10876 | ||
antibiotic | Q12187 | ||
drug delivery system | Q64829245 | ||
P304 | page(s) | 116-133 | |
P577 | publication date | 2016-12-15 | |
2018-02-01 | |||
P1433 | published in | Parasitology | Q15753259 |
P1476 | title | Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target | |
P478 | volume | 145 |
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Q97418212 | Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis |
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Q89494842 | Digging Deeper to Save the Old Anti-tuberculosis Target: D-Alanine-D-Alanine Ligase With a Novel Inhibitor, IMB-0283 |
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