scholarly article | Q13442814 |
P50 | author | Ming Tan | Q57152427 |
Jung-Hyun Kim | Q61918827 | ||
Ssang-Taek Lim | Q64515245 | ||
Eun-Young Ahn | Q84476133 | ||
P2093 | author name string | Gang Huang | |
Eun Young Park | |||
Joshua K Stone | |||
Richard M Myers | |||
Erik K Flemington | |||
Xiaomei Yan | |||
Hyeonsoo Park | |||
Thomas W Butler | |||
Florencia Pauli-Behn | |||
Melody C Baddoo | |||
P2860 | cites work | Menin critically links MLL proteins with LEDGF on cancer-associated target genes | Q37217351 |
Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription | Q37255927 | ||
Gfi1-cells and circuits: unraveling transcriptional networks of development and disease | Q37767120 | ||
Emerging epigenetic targets and therapies in cancer medicine | Q38010385 | ||
The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis | Q38015891 | ||
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells | Q38319231 | ||
Targeting the MLL complex in castration-resistant prostate cancer | Q38893281 | ||
New discoveries of old SON: a link between RNA splicing and cancer | Q39351268 | ||
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. | Q39643148 | ||
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis | Q40359760 | ||
Let's sp(l)ice up pluripotency! | Q42883138 | ||
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells | Q43734888 | ||
Menin links estrogen receptor activation to histone H3K4 trimethylation | Q83228702 | ||
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription | Q22001458 | ||
SON controls cell-cycle progression by coordinated regulation of RNA splicing | Q24299993 | ||
Gadd45 stress sensors in malignancy and leukemia | Q24600698 | ||
Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein | Q27670797 | ||
High-resolution profiling of histone methylations in the human genome | Q27860906 | ||
COMPASS: a complex of proteins associated with a trithorax-related SET domain protein | Q27931344 | ||
Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes | Q28144204 | ||
A cDNA clone for a novel nuclear protein with DNA binding activity | Q28201469 | ||
Transcription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON | Q28212953 | ||
SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster | Q28283462 | ||
SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells | Q28298055 | ||
A chromatin landmark and transcription initiation at most promoters in human cells | Q29547180 | ||
Regulation of MLL1 H3K4 methyltransferase activity by its core components | Q29614518 | ||
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia | Q30425903 | ||
p21 in cancer: intricate networks and multiple activities | Q30436015 | ||
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. | Q30537596 | ||
Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders | Q33374851 | ||
MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele. | Q33694927 | ||
An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain | Q33761102 | ||
The role of SON in splicing, development, and disease | Q34066845 | ||
WRAD: enabler of the SET1-family of H3K4 methyltransferases | Q34278347 | ||
Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes | Q34554800 | ||
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations | Q35025549 | ||
Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo | Q35557914 | ||
Son maintains accurate splicing for a subset of human pre-mRNAs | Q35672134 | ||
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L. | Q35898171 | ||
Histone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo | Q36438203 | ||
P433 | issue | 6 | |
P304 | page(s) | 859-873 | |
P577 | publication date | 2016-03-01 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes | |
P478 | volume | 61 |
Q99412626 | A de novo heterozygous variant in the SON gene is associated with Zhu-Tokita-Takenouchi-Kim syndrome |
Q38735423 | Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems |
Q64882693 | Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy. |
Q36174308 | Clustering of mRNA-Seq data based on alternative splicing patterns |
Q90569904 | Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair |
Q58801085 | DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity |
Q29147448 | De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome |
Q64101011 | Differential isoform expression and alternative splicing in sex determination in mice |
Q89055219 | Germline Stem Cell Heterogeneity Supports Homeostasis in Drosophila |
Q55279675 | MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. |
Q64949879 | Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler. |
Q90038226 | SON haploinsufficiency causes impaired pre-mRNA splicing of CAKUT genes and heterogeneous renal phenotypes |
Q103029141 | SON inhibits megakaryocytic differentiation via repressing RUNX1 and the megakaryocytic gene expression program in acute megakaryoblastic leukemia |
Q47814736 | The future: genetics advances in MEN1 therapeutic approaches and management strategies. |
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