Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation

scientific article published on 20 February 2016

Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3233/JAD-150982
P698PubMed publication ID26923021

P50authorInhee Mook-JungQ91432207
P2093author name stringYoonhee Kim
Hye Young Jang
Chaeyoung Kim
P2860cites workCholesterol, lipid rafts, and diseaseQ24553188
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Gamma-secretase activity is present in rafts but is not cholesterol-dependentQ44667739
DNA damage-inducing agents elicit gamma-secretase activation mediated by oxidative stressQ46637801
A detergent-insoluble membrane compartment contains A beta in vivoQ47982783
Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis.Q50528123
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P433issue4
P304page(s)1057-1068
P577publication date2016-02-20
P1433published inJournal of Alzheimer's DiseaseQ6294755
P1476titleInhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation
P478volume51