scholarly article | Q13442814 |
P50 | author | Nicola T Wood | Q57422668 |
Thimo Kurz | Q38803395 | ||
P2093 | author name string | Axel Knebel | |
Yann Thomas | |||
Matthew J Keuss | |||
Robin Mcarthur | |||
P2860 | cites work | Genome engineering using the CRISPR-Cas9 system | Q22122027 |
UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation | Q24291831 | ||
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae | Q24306410 | ||
Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex | Q24310859 | ||
Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases | Q24313433 | ||
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation | Q24314520 | ||
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification | Q24316067 | ||
DCUN1D3, a novel UVC-responsive gene that is involved in cell cycle progression and cell growth | Q24317079 | ||
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation | Q24317319 | ||
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes | Q24337489 | ||
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases | Q24337709 | ||
CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex | Q24337718 | ||
RNA-guided human genome engineering via Cas9 | Q24598394 | ||
SCCRO promotes glioma formation and malignant progression in mice | Q24633442 | ||
Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8 | Q27640736 | ||
Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation | Q27649565 | ||
A Dual E3 Mechanism for Rub1 Ligation to Cdc53 | Q27664416 | ||
Structural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation Enzymes | Q27675332 | ||
The ubiquitin system | Q27860803 | ||
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. | Q27931858 | ||
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex | Q27933259 | ||
A novel protein modification pathway related to the ubiquitin system | Q27938072 | ||
USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses | Q28115910 | ||
NEDD8 Overexpression Results in Neddylation of Ubiquitin Substrates by the Ubiquitin Pathway | Q63976960 | ||
Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome | Q28187304 | ||
Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint | Q28212584 | ||
Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA | Q28292106 | ||
Cullin 4A associates with the UV-damaged DNA-binding protein DDB | Q28619483 | ||
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer | Q29616732 | ||
The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells | Q34012408 | ||
Protein neddylation: beyond cullin-RING ligases | Q34042816 | ||
Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization | Q34314163 | ||
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage | Q34353149 | ||
Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites. | Q34474077 | ||
Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas | Q34571296 | ||
SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1) | Q34683293 | ||
Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate | Q34984389 | ||
The TFIIH subunit Tfb3 regulates cullin neddylation | Q35266319 | ||
Mono-ubiquitination drives nuclear export of the human DCN1-like protein hDCNL1 | Q35311062 | ||
Improved genome editing in human cell lines using the CRISPR method | Q35321474 | ||
The COP9 signalosome is vital for timely repair of DNA double-strand breaks | Q35786094 | ||
Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia | Q36159459 | ||
Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins | Q36850952 | ||
Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series | Q36946992 | ||
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes | Q37282361 | ||
The cullin protein family | Q37873586 | ||
Emerging roles of E3 ubiquitin ligases in autophagy | Q38122815 | ||
SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair. | Q38855830 | ||
The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction | Q39986392 | ||
CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire | Q40136931 | ||
Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes | Q41141041 | ||
Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia. | Q41482346 | ||
SCCRO (DCUN1D1) promotes nuclear translocation and assembly of the neddylation E3 complex | Q42700446 | ||
CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing | Q47069271 | ||
Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. | Q47069590 | ||
E-CRISP: fast CRISPR target site identification | Q48332892 | ||
CSN- and CAND1-dependent remodelling of the budding yeast SCF complex. | Q50336194 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1441-1454 | |
P577 | publication date | 2016-02-18 | |
P1433 | published in | Journal of Cell Science | Q1524177 |
P1476 | title | Characterization of the mammalian family of DCN-type NEDD8 E3 ligases | |
P478 | volume | 129 |
Q42621169 | A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation |
Q38701253 | Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. |
Q52729296 | Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression. |
Q50296656 | NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex |
Q50296650 | NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex |
Q112993662 | NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex |
Q112993708 | NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex |
Q50296654 | NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex |
Q45317714 | Neddylation |
Q88080896 | Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation |
Q41543057 | SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms. |
Q48594712 | Squamous cell carcinoma-related oncogene (SCCRO) neddylates Cul3 protein to selectively promote midbody localization and activity of Cul3KLHL21 protein complex during abscission. |
Q55488054 | The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation. |
Q63976958 | Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death |
Search more.