Transforming growth factor-β signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells

scientific article published on 26 August 2015

Transforming growth factor-β signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PROS.23060
P698PubMed publication ID26392321

P50authorJohn FavateQ57411425
P2093author name stringRobert A Sikes
Fayth L Miles
Mehrnoosh Soori
Senem Kurtoglu
Chris Ahmer
P2860cites workParacrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cellsQ42382543
Bone histology at autopsy and matched bone scintigraphy findings in patients with hormone refractory prostate cancer: the effect of bisphosphonate therapy on bone scintigraphy resultsQ44410099
Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cellsQ47746078
Androgen-Independent Prostate Cancer Is a Heterogeneous Group of DiseasesQ57693579
Crosstalk between apoptosis, necrosis and autophagyQ26829723
Coculture with prostate cancer cells alters endoglin expression and attenuates transforming growth factor-beta signaling in reactive bone marrow stromal cellsQ28306936
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epitheliaQ29618875
Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environmentQ30304016
The lethal phenotype of cancer: the molecular basis of death due to malignancyQ34005113
Neuroendocrine differentiation in human prostate cancer. Morphogenesis, proliferation and androgen receptor statusQ34106904
Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cellsQ34340236
Potential clinical value of circulating chromogranin A in patients with prostate carcinomaQ34474224
The bone marrow vascular niche: home of HSC differentiation and mobilizationQ36262585
Current insights into the role of transforming growth factor-beta in bone resorption.Q36283949
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formationQ37307155
Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorptionQ38275140
Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axisQ39305976
Interleukin-6: a bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cellsQ39375270
Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signalingQ39415532
Does over-expression of transforming growth factor-beta account for the increased morbidity in African-Americans?: possible clinical study and therapeutic implicationsQ39874677
TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cellsQ40029812
Mutually antagonistic effects of androgen and activin in the regulation of prostate cancer cell growthQ40605883
LNCaP progression model of human prostate cancer: androgen-independence and osseous metastasisQ40869882
Androgen-independent growth is induced by neuropeptides in human prostate cancer cell linesQ40915126
Upregulation of endothelin 1 and its precursor by IL-1beta, TNF-alpha, and TGF-beta in the PC3 human prostate cancer cell lineQ40965622
P433issue15
P921main subjectprostate cancerQ181257
cell deathQ2383867
P304page(s)1802-1813
P577publication date2015-08-26
P1433published inThe ProstateQ7758608
P1476titleTransforming growth factor-β signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells
P478volume75

Reverse relations

cites work (P2860)
Q64230141Downregulation of miR143/145 gene cluster expression promotes the aortic media degeneration process via the TGF-β1 signaling pathway
Q36261090Fluoride Regulate Osteoblastic Transforming Growth Factor-β1 Signaling by Mediating Recycling of the Type I Receptor ALK5
Q38717566Identification of Fibulin-1 as a Human Bone Marrow Stromal (HS-5) Cell-Derived Factor That Induces Human Prostate Cancer Cell Death
Q90227984Neuroendocrine Differentiation of Prostate Cancer-An Intriguing Example of Tumor Evolution at Play
Q38904873Synergistic immunologic targets for the treatment of prostate cancer

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