review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1002/WSBM.1340 |
P698 | PubMed publication ID | 27240056 |
P2093 | author name string | Dina Petranovic | |
Xin Chen | |||
P2860 | cites work | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 |
Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration | Q24311376 | ||
Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3) | Q24314548 | ||
The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathway | Q24317229 | ||
Recognition of the polyubiquitin proteolytic signal | Q24530006 | ||
Global prevalence of dementia: a Delphi consensus study | Q24603249 | ||
Genetic aspects of Alzheimer disease | Q24604373 | ||
The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates | Q24605908 | ||
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? | Q24617857 | ||
Akt and CHIP coregulate tau degradation through coordinated interactions | Q24656202 | ||
Autosomal Dominant Alzheimer Disease: A Unique Resource to Study CSF Biomarker Changes in Preclinical AD | Q26801666 | ||
Neuropathological alterations in Alzheimer disease | Q27003314 | ||
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody | Q27663589 | ||
Structural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and Neurotoxicity | Q27664383 | ||
The ubiquitin system | Q27860803 | ||
Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism | Q27931319 | ||
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. | Q27935265 | ||
Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome | Q27937521 | ||
Conformational disease | Q28244193 | ||
Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients | Q28258349 | ||
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy | Q28282855 | ||
Mechanism, specificity and structure of the deubiquitinases | Q28302974 | ||
Mutant ubiquitin UBB+1 induces mitochondrial fusion by destabilizing mitochondrial fission-specific proteins and confers resistance to oxidative stress-induced cell death in astrocytic cells | Q28539822 | ||
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP | Q28593538 | ||
A proteomics approach to understanding protein ubiquitination | Q29547312 | ||
Recognition and processing of ubiquitin-protein conjugates by the proteasome | Q29547616 | ||
Ubiquitin: structures, functions, mechanisms | Q29616462 | ||
Getting started with yeast | Q29618025 | ||
Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates | Q33408783 | ||
Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: importance of lipid homeostasis | Q33975871 | ||
Assembly, structure, and function of the 26S proteasome. | Q33988314 | ||
Molecular misreading: a new type of transcript mutation expressed during aging. | Q34109702 | ||
Quality control of mRNA function | Q34156109 | ||
Disease-specific accumulation of mutant ubiquitin as a marker for proteasomal dysfunction in the brain | Q34274379 | ||
The role of serotonin in respiratory function and dysfunction | Q34357201 | ||
Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells | Q34419722 | ||
Combating neurodegenerative disease with chemical probes and model systems | Q38261089 | ||
The role of protein clearance mechanisms in organismal ageing and age-related diseases. | Q38284376 | ||
Molecular misreading: the frequency of dinucleotide deletions in neuronal mRNAs for beta-amyloid precursor protein and ubiquitin B. | Q38333442 | ||
Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins. | Q38393072 | ||
Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions. | Q39703142 | ||
Minimal length requirement for proteasomal degradation of ubiquitin-dependent substrates | Q39939165 | ||
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases | Q40056959 | ||
Somatic mutations in the brain: relationship to aging? | Q40416494 | ||
Mixed-linkage ubiquitin chains send mixed messages | Q40703860 | ||
Amyloid-β peptide-induced cytotoxicity and mitochondrial dysfunction in yeast. | Q40760450 | ||
Molecular misreading: the occurrence of frameshift proteins in different diseases | Q42601184 | ||
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation | Q42917499 | ||
Proteasomal degradation of tau protein | Q44163168 | ||
Proteasome-mediated degradation of tau proteins occurs independently of the chymotrypsin-like activity by a nonprocessive pathway | Q44251448 | ||
Alzheimer's associated variant ubiquitin causes inhibition of the 26S proteasome and chaperone expression | Q44518998 | ||
Microtubule-associated protein tau is a substrate of ATP/Mg(2+)-dependent proteasome protease system | Q45062378 | ||
Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases | Q45293883 | ||
Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration | Q45294083 | ||
Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation. | Q46031118 | ||
Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease | Q48219211 | ||
Mutations in RNA: a first example of molecular misreading in Alzheimer's disease | Q48404361 | ||
Possible new cause of Alzheimer's disease found | Q48553732 | ||
Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin | Q48944295 | ||
Mutant vasopressin precursors in the human hypothalamus: evidence for neuronal somatic mutations in man. | Q49039426 | ||
Mutant ubiquitin decreases amyloid β plaque formation in a transgenic mouse model of Alzheimer's disease. | Q54497362 | ||
Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. | Q34490657 | ||
HUWE1 and TRIP12 collaborate in degradation of ubiquitin-fusion proteins and misframed ubiquitin | Q34500475 | ||
Genetics of Alzheimer disease | Q34604101 | ||
Yeast: an experimental organism for modern biology | Q34687053 | ||
Asymmetric mitosis: Unequal segregation of proteins destined for degradation | Q34782639 | ||
Serpinopathies and the conformational dementias | Q34932013 | ||
Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes | Q34994389 | ||
Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity | Q35109915 | ||
The amazing web of post-transcriptional gene control: the sum of small changes can make for significant consequences | Q35210908 | ||
Genetics and the pathobiology of ageing | Q35211822 | ||
Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway | Q35344983 | ||
Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin | Q35529325 | ||
Frameshift mutations at two hotspots in vasopressin transcripts in post-mitotic neurons | Q35550396 | ||
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. | Q35558459 | ||
Extended ubiquitin species are protein-based DUB inhibitors | Q35739138 | ||
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast | Q35763361 | ||
The novel functions of ubiquitination in signaling | Q35804780 | ||
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy | Q35955959 | ||
Protein quality control in Alzheimer's disease by the ubiquitin proteasome system. | Q35974765 | ||
Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all. | Q36092032 | ||
Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients | Q36105261 | ||
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting | Q36226090 | ||
Molecular biology's impact on our understanding of aging | Q36246851 | ||
Yeast systems biology to unravel the network of life | Q36405205 | ||
The projected effect of risk factor reduction on Alzheimer's disease prevalence | Q36825862 | ||
Abeta inhibits the proteasome and enhances amyloid and tau accumulation | Q37147213 | ||
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. | Q37200867 | ||
Lateral parabrachial nucleus mediates shortening of expiration and increase of inspiratory drive during hypercapnia | Q37218603 | ||
Can yeast systems biology contribute to the understanding of human disease? | Q37272910 | ||
Inhibition of the ubiquitin-proteasome system in Alzheimer's disease. | Q37387675 | ||
Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease | Q37456990 | ||
Systems biology of yeast cell death | Q37970448 | ||
Gene expression profiling in human neurodegenerative disease | Q38034387 | ||
P433 | issue | 4 | |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 300-313 | |
P577 | publication date | 2016-05-30 | |
P1433 | published in | Wiley interdisciplinary reviews. Systems biology and medicine | Q26842017 |
P1476 | title | Role of frameshift ubiquitin B protein in Alzheimer's disease | |
P478 | volume | 8 |