| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1047710073 |
| P356 | DOI | 10.1007/S00125-015-3669-6 |
| P698 | PubMed publication ID | 26099855 |
| P50 | author | Gökhan Hotamışlıgil | Q6033455 |
| Piero Marchetti | Q37382607 | ||
| Mariana Igoillo-Esteve | Q64358596 | ||
| Marco Bugliani | Q79304855 | ||
| Feyza Engin | Q80764842 | ||
| P2093 | author name string | Olatz Villate | |
| Decio L Eizirik | |||
| Flora Brozzi | |||
| Marina Casimir | |||
| Fabio A Grieco | |||
| Isabelle Millard | |||
| Jenny Barthson | |||
| Joana M Oliveira | |||
| Miguel Lopes | |||
| Tarlliza R Nardelli | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
| GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis | Q24302321 | ||
| Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury | Q24563635 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance | Q28574313 | ||
| Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells | Q28574877 | ||
| STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation | Q28575333 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids | Q29616817 | ||
| Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines | Q29619317 | ||
| Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model | Q30421540 | ||
| The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. | Q33300966 | ||
| Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells | Q33604490 | ||
| Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway | Q33943895 | ||
| A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells | Q33947078 | ||
| Cytokines suppress human islet function irrespective of their effects on nitric oxide generation | Q34143253 | ||
| The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells | Q34162699 | ||
| The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines | Q34192894 | ||
| Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes | Q34213205 | ||
| A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis | Q34495385 | ||
| Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans | Q35085188 | ||
| Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice | Q36047577 | ||
| C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells | Q36311167 | ||
| Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells | Q36862771 | ||
| Initiation and execution of lipotoxic ER stress in pancreatic beta-cells | Q36910693 | ||
| The role for endoplasmic reticulum stress in diabetes mellitus | Q37019672 | ||
| PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis | Q37193767 | ||
| Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program | Q37360298 | ||
| Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. | Q37429250 | ||
| The role of inflammation in insulitis and beta-cell loss in type 1 diabetes | Q37437153 | ||
| ER stress in pancreatic beta cells: the thin red line between adaptation and failure | Q37697386 | ||
| Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases. | Q37804462 | ||
| Endoplasmic reticulum stress and pancreatic β-cell death | Q37860493 | ||
| Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction | Q37863796 | ||
| A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion | Q38271856 | ||
| Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells | Q38331321 | ||
| Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells | Q39562673 | ||
| Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells | Q40623131 | ||
| Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release | Q40851108 | ||
| The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells | Q40857466 | ||
| Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells | Q43585447 | ||
| Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt. | Q46678812 | ||
| Temporal profiling of cytokine-induced genes in pancreatic β-cells by meta-analysis and network inference. | Q50693557 | ||
| Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes | Q57920468 | ||
| Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays | Q73831600 | ||
| Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR | Q77753107 | ||
| Contribution of ductal cells to cytokine responses by human pancreatic islets | Q77804885 | ||
| Reevaluation of the Griess method for determining NO/NO2- in aqueous and protein-containing samples | Q78112779 | ||
| Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells | Q81234667 | ||
| Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets | Q81914032 | ||
| Use of RNA interference to investigate cytokine signal transduction in pancreatic beta cells | Q82751765 | ||
| Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation | Q82927575 | ||
| P433 | issue | 10 | |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P304 | page(s) | 2307-2316 | |
| P577 | publication date | 2015-06-23 | |
| P1433 | published in | Diabetologia | Q5270140 |
| P1476 | title | Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms | |
| P478 | volume | 58 |
| Q38765352 | Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity |
| Q55104419 | Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents. |
| Q95660427 | An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells |
| Q61798455 | Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes |
| Q93205455 | Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic β-Cells to Type 2 Diabetes |
| Q91867818 | Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells |
| Q64070945 | Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells |
| Q94571793 | Distinct secretion pattern of serum proinsulin in different types of diabetes |
| Q47915028 | Dual Role of Nitric Oxide in Regulating the Response of β Cells to DNA Damage |
| Q36986979 | ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes |
| Q48144907 | EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium. |
| Q55456504 | Endoplasmic Reticulum Stress in Metabolic Disorders. |
| Q26749276 | Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation |
| Q33562757 | Eutopic/ectopic endometrial apoptosis initiated by bilateral uterine artery occlusion: A new therapeutic mechanism for uterus-sparing surgery in adenomyosis |
| Q92251738 | Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia |
| Q64911734 | Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity. |
| Q33685887 | Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis |
| Q41689680 | Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis |
| Q38781238 | Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells. |
| Q55283549 | IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases. |
| Q94603121 | Identification of microRNA-mRNA regulatory networks and pathways related to retinoblastoma across human and mouse |
| Q90729643 | Inflammation and Monocyte Recruitment due to Aging and Mechanical Stretch in Alveolar Epithelium are Inhibited by the Molecular Chaperone 4-phenylbutyrate |
| Q57786914 | Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes |
| Q47587029 | Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α. |
| Q36238919 | Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight |
| Q60954057 | Injury factors alter miRNAs profiles of exosomes derived from islets and circulation |
| Q50965572 | Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes. |
| Q36990222 | Interferon-γ-Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sjögren Syndrome |
| Q37613827 | JNK at the crossroad of obesity, insulin resistance, and cell stress response. |
| Q60912534 | MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity |
| Q38951189 | Mass production of functional human pancreatic β-cells: why and how? |
| Q48219089 | Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets |
| Q36163240 | MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells. |
| Q38721830 | Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival. |
| Q38977178 | Novel Treatment of Chronic Graft-Versus-Host Disease in Mice Using the ER Stress Reducer 4-Phenylbutyric Acid |
| Q64991590 | Novel elucidation and treatment of pancreatic chronic graft-versus-host disease in mice. |
| Q39457205 | Pancreatic size and fat content in diabetes: A systematic review and meta-analysis of imaging studies. |
| Q48724578 | Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF). |
| Q58702444 | Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes |
| Q94600515 | Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure |
| Q93162571 | Phlda3 regulates beta cell survival during stress |
| Q92405630 | Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells |
| Q38743233 | Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis. |
| Q55260956 | Regulation of Cytokine Production by the Unfolded Protein Response; Implications for Infection and Autoimmunity. |
| Q61801441 | Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine-Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy |
| Q38755624 | Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines |
| Q64057066 | Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress |
| Q40409465 | Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. |
| Q58694047 | The Effect of Chronic Inflammation and Oxidative and Endoplasmic Reticulum Stress in the Course of Metabolic Syndrome and Its Therapy |
| Q91063059 | The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes |
| Q38814499 | The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro |
| Q46268042 | The species origin of the cellular microenvironment influences markers of beta cell fate and function in EndoC-βH1 cells |
| Q58595054 | The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes |
| Q47304202 | Transcription Factor C/EBP Homologous Protein in Health and Diseases. |
| Q91364063 | Tumor Microenvironment Regulation by the Endoplasmic Reticulum Stress Transmission Mediator Golgi Protein 73 in Mice |
| Q37065973 | Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells |
| Q39398068 | Understanding type 1 diabetes through proteomics |
| Q52607218 | β-Cell Autophagy in Diabetes Pathogenesis. |
| Q38828883 | β-cell differentiation status in type 2 diabetes. |
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