Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment

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Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.9528
P932PMC publication ID5173087
P698PubMed publication ID27223437

P50authorBahriye AktasQ83188500
Pawel MachQ87769838
P2093author name stringSabine Kasimir-Bauer
Rainer Kimmig
Maren Bredemeier
Mitra Tewes
Philippos Edimiris
Jenny Wagner
Doreen Schellbach
P2860cites workExpression of stem cell and epithelial-mesenchymal transition markers in circulating tumor cells of breast cancer patientsQ21284707
HER-2 gene amplification can be acquired as breast cancer progressesQ24563115
Circulating tumor cells: approaches to isolation and characterizationQ24631347
Prognostic value of Aurora kinase A (AURKA) expression among solid tumor patients: a systematic review and meta-analysisQ27024067
Epidermal growth factor-related peptides and their receptors in human malignanciesQ28293442
Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell linesQ28483475
Molecular biomarker analyses using circulating tumor cellsQ28749394
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapyQ29617584
Circulating tumor cells, disease progression, and survival in metastatic breast cancerQ29619276
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient dataQ30779447
Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cellsQ33285246
HER2-positive circulating tumor cells in breast cancerQ33802925
Circulating tumor cells predict survival in early average-to-high risk breast cancer patientsQ33958981
Gene expression profile of circulating tumor cells in breast cancer by RT-qPCR.Q34038793
Co-expression of putative stemness and epithelial-to-mesenchymal transition markers on single circulating tumour cells from patients with early and metastatic breast cancerQ34168398
Circulating tumor cells and response to chemotherapy in metastatic breast cancer: SWOG S0500Q34402487
Molecular profiling of single circulating tumor cells with diagnostic intentionQ34542660
The HER family and cancer: emerging molecular mechanisms and therapeutic targetsQ34558080
Triple-negative breast cancer: clinical features and patterns of recurrenceQ34658655
Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancerQ35007782
Epithelial to mesenchymal transition markers expressed in circulating tumour cells of early and metastatic breast cancer patients.Q35558093
Cytokeratin-19 mRNA-positive circulating tumor cells during follow-up of patients with operable breast cancer: prognostic relevance for late relapse.Q35558096
The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patientsQ35619770
Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancerQ35653820
Expression of truncated human epidermal growth factor receptor 2 on circulating tumor cells of breast cancer patients.Q35749122
Multimarker Analysis of Circulating Tumor Cells in Peripheral Blood of Metastatic Breast Cancer Patients: A Step Forward in Personalized MedicineQ35909577
TBCRC 001: randomized phase II study of cetuximab in combination with carboplatin in stage IV triple-negative breast cancerQ36145430
Prognostic Value of EMT-Circulating Tumor Cells in Metastatic Breast Cancer Patients Undergoing High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell TransplantationQ36316580
Expression of stem cell and epithelial-mesenchymal transition markers in primary breast cancer patients with circulating tumor cellsQ36393149
Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer.Q36406697
HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab.Q36693285
Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sortingQ36747333
Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancerQ36934364
Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patientsQ37038658
The prognostic implications of circulating tumor cells in patients with breast cancerQ37079905
Role of epidermal growth factor receptor in breast cancerQ37320346
Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patientsQ37360176
Detection and characterization of circulating tumor cells in blood of primary breast cancer patients by RT-PCR and comparison to status of bone marrow disseminated cellsQ37360230
Gene expression markers in circulating tumor cells may predict bone metastasis and response to hormonal treatment in breast cancerQ37560932
Recent advances in the molecular characterization of circulating tumor cellsQ37693504
Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker?Q37694203
Molecular mechanisms of metastasis in breast cancer--clinical applicationsQ37801264
Circulating tumor cells in breast cancer: detection systems, molecular characterization, and future challengesQ37904507
HER2-positive DTCs/CTCs in breast cancerQ38004902
Targeting HER family in HER2-positive metastatic breast cancer: potential biomarkers and novel targeted therapies.Q38364887
Gene expression profiling of circulating tumor cells in breast cancer.Q38470332
PIK3CA mutational status in circulating tumor cells can change during disease recurrence or progression in patients with breast cancerQ38940270
Elimination of EGFR-expressing circulating tumor cells in patients with metastatic breast cancer treated with gefitinibQ39027480
Molecular characterization of circulating tumor cells in breast cancer by a liquid bead array hybridization assayQ39606153
Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trialQ39712731
Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer.Q39822968
Trastuzumab-induced HER reprogramming in "resistant" breast carcinoma cellsQ39874639
Prognostic markers in triple-negative breast cancerQ42505075
Challenges in circulating tumour cell researchQ43500645
Prognostic relevance of viable circulating tumor cells detected by EPISPOT in metastatic breast cancer patientsQ44115632
Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGen AdnaTest BreastCancer Select/Detect™ versus Veridex CellSearch™ systemQ45733272
Molecular profiling and predictive value of circulating tumor cells in patients with metastatic breast cancer: an option for monitoring response to breast cancer related therapiesQ46446226
HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: a single-institution experience of 2,279 cases and comparison of dual-color and single-color scoringQ47583436
Comparison of estrogen and progesterone receptor status of circulating tumor cells and the primary tumor in metastatic breast cancer patientsQ47586016
Circulating tumour cells in non-metastatic breast cancer: a prospective studyQ47652073
Cytokeratin-19 mRNA-positive circulating tumor cells after adjuvant chemotherapy in patients with early breast cancer.Q51744140
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trialQ51751068
Circulating tumor cells versus imaging--predicting overall survival in metastatic breast cancer.Q53012804
The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer.Q53127630
Gene expression profiles of circulating tumor cells versus primary tumors in metastatic breast cancer.Q54169673
mRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patients.Q54377128
Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significanceQ69367626
Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancerQ69900051
Monitoring expression of HER-2 on circulating epithelial cells in patients with advanced breast cancerQ78347889
Predictive and prognostic value of peripheral blood cytokeratin-19 mRNA-positive cells detected by real-time polymerase chain reaction in node-negative breast cancer patientsQ83978338
High independent prognostic and predictive value of circulating tumor cells compared with serum tumor markers in a large prospective trial in first-line chemotherapy for metastatic breast cancer patientsQ84277674
Gene expression profiles in circulating tumor cells to predict prognosis in metastatic breast cancer patientsQ86179689
P433issue27
P407language of work or nameEnglishQ1860
P921main subjectmetastatic breast cancerQ12859063
P304page(s)41677-41690
P577publication date2016-05-20
P1433published inOncotargetQ1573155
P1476titleEstablishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment
P478volume7

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cites work (P2860)
Q91810001CTCs Expression Profiling for Advanced Breast Cancer Monitoring
Q64245475Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer
Q39339875Circulating Tumor Cells as Cancer Biomarkers in the Clinic.
Q33674656Comparison of the PI3KCA pathway in circulating tumor cells and corresponding tumor tissue of patients with metastatic breast cancer
Q41472132EMT-like circulating tumor cells in ovarian cancer patients are enriched by platinum-based chemotherapy
Q33648465ERCC1-expressing circulating tumor cells as a potential diagnostic tool for monitoring response to platinum-based chemotherapy and for predicting post-therapeutic outcome of ovarian cancer
Q41233528Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy
Q64243735Profiling of Invasive Breast Carcinoma Circulating Tumour Cells-Are We Ready for the 'Liquid' Revolution?
Q26741223The Significance of Epithelial-to-Mesenchymal Transition for Circulating Tumor Cells

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