review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Markus Rehm | |
Emilie M Charles | |||
P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas | Q24290531 | ||
Analysis of APAF-1 expression in human cutaneous melanoma progression | Q24315147 | ||
XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization | Q27645534 | ||
Global cancer statistics, 2002 | Q27860562 | ||
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | Q27860674 | ||
Identification of XAF1 as an antagonist of XIAP anti-Caspase activity | Q28200039 | ||
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function | Q28276098 | ||
Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis | Q28567791 | ||
Final version of 2009 AJCC melanoma staging and classification | Q29614803 | ||
Mitochondria and cell death: outer membrane permeabilization and beyond | Q29615459 | ||
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors | Q29619686 | ||
IAP proteins: blocking the road to death's door | Q29619844 | ||
Apoptosis: controlled demolition at the cellular level | Q29620114 | ||
Systems analysis of apoptosis protein expression allows the case-specific prediction of cell death responsiveness of melanoma cells | Q30549646 | ||
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias | Q31379722 | ||
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma | Q31984891 | ||
Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas | Q33390467 | ||
From computational modelling of the intrinsic apoptosis pathway to a systems-based analysis of chemotherapy resistance: achievements, perspectives and challenges in systems medicine. | Q33720383 | ||
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells | Q33807797 | ||
Survivin expression by metastatic melanoma predicts poor disease outcome in patients receiving adjuvant polyvalent vaccine | Q33887196 | ||
Granzymes in cancer and immunity | Q34092936 | ||
XAF1 expression is significantly reduced in human melanoma | Q34378197 | ||
Analyzing proteome topology and function by automated multidimensional fluorescence microscopy | Q34570499 | ||
Cutaneous melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Q34642874 | ||
Caspases in cell survival, proliferation and differentiation. | Q34652977 | ||
Measuring and modeling apoptosis in single cells | Q34921455 | ||
Mammalian mitochondrial IAP binding proteins | Q35120735 | ||
Apoptosis and melanoma chemoresistance | Q35146577 | ||
Melanoma inhibitor of apoptosis protein is expressed differentially in melanoma and melanocytic naevus, but similarly in primary and metastatic melanomas | Q35588764 | ||
The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization | Q35632517 | ||
Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways | Q36184769 | ||
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP. | Q36320565 | ||
XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells | Q36371312 | ||
BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma | Q36418729 | ||
Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach | Q36907121 | ||
Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells | Q36974839 | ||
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue | Q37031799 | ||
Reduced Apaf-1 expression in human cutaneous melanomas | Q37355450 | ||
BH3-only proteins: Orchestrators of apoptosis | Q37819153 | ||
The molecular machinery regulating apoptosis signal transduction and its implication in human physiology and pathophysiologies. | Q37824333 | ||
TRAIL signaling and synergy mechanisms used in TRAIL-based combination therapies | Q37974875 | ||
Role of the apoptotic and mitotic regulator survivin in melanoma. | Q37979778 | ||
Targeting IAP proteins for therapeutic intervention in cancer | Q37980321 | ||
The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome | Q37992385 | ||
The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy. | Q38052387 | ||
New developments in biomarkers for melanoma | Q38075415 | ||
Apoptosome structure, assembly, and procaspase activation. | Q38096568 | ||
IAPs, regulators of innate immunity and inflammation. | Q38203437 | ||
Immunohistochemical detection of XIAP in melanoma | Q38427860 | ||
APG350 induces superior clustering of TRAIL receptors and shows therapeutic antitumor efficacy independent of cross-linking via Fcγ receptors | Q39084817 | ||
Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells | Q39148992 | ||
Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells | Q39256885 | ||
Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization. | Q39265529 | ||
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation | Q39647076 | ||
Born to be alive: a role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment | Q39661214 | ||
Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway | Q39867609 | ||
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases | Q40341729 | ||
Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents | Q40502676 | ||
Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma | Q40626082 | ||
Elevated procaspase levels in human melanoma | Q40789256 | ||
Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein | Q41834899 | ||
Targeting X-linked inhibitor of apoptosis protein to increase the efficacy of endoplasmic reticulum stress-induced apoptosis for melanoma therapy. | Q43045813 | ||
Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. | Q43188994 | ||
Allelic imbalance on 12q22-23 in serum circulating DNA of melanoma patients predicts disease outcome | Q44829269 | ||
Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma | Q47573472 | ||
Expression of AP‐2α, c‐kit, and cleaved caspase‐6 and ‐3 in naevi and malignant melanomas of the skin. A possible role for caspases in melanoma progression? | Q47596125 | ||
Allelic imbalance of 12q22-23 associated with APAF-1 locus correlates with poor disease outcome in cutaneous melanoma | Q47937033 | ||
Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy. | Q50507805 | ||
Caspases and inhibitor of apoptosis proteins in cutaneous and mucosal melanoma: expression profile and clinicopathologic significance. | Q51779084 | ||
Apaf-1 expression in human cutaneous melanoma progression and in pigmented nevi. | Q53350290 | ||
XIAP, the guardian angel | Q74122492 | ||
Decreased expression of Apaf-1 with progression of melanoma | Q81268045 | ||
P433 | issue | 3 | |
P921 | main subject | biomarker | Q864574 |
P304 | page(s) | e964037 | |
P577 | publication date | 2014-07-01 | |
P1433 | published in | Molecular & cellular oncology | Q27725948 |
P1476 | title | Key regulators of apoptosis execution as biomarker candidates in melanoma | |
P478 | volume | 1 |
Q38708463 | Computed determination of the in vitro optimal chemocombinations of sphaeropsidin A with chemotherapeutic agents to combat melanomas |
Q47101451 | Eyes absent gene (EYA1) is a pathogenic driver and a therapeutic target for melanoma |
Q64040347 | Gene-Specific Intron Retention Serves as Molecular Signature that Distinguishes Melanoma from Non-Melanoma Cancer Cells in Greek Patients |
Q89701293 | Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma |
Q58556825 | Overexpression of IRS-4 Correlates with Procaspase 3 Levels in Tumoural Tissue of Patients with Colorectal Cancer |
Q38701274 | The Role of Radiofrequency Hyperthermia in The Radiosensitization of A Human Prostate Cancer Cell Line |
Q55457478 | Voltage-gated potassium channel blocker 4-aminopyridine induces glioma cell apoptosis by reducing expression of microRNA-10b-5p. |
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