| scholarly article | Q13442814 |
| P50 | author | Su-Chang Lin | Q72125061 |
| P2093 | author name string | Hao Wu | |
| Jiahuai Han | |||
| Yu-Chih Lo | |||
| Yihua Huang | |||
| Miao Lu | |||
| David Myszka | |||
| Rebecca Rich | |||
| Young Jun Kang | |||
| P2860 | cites work | Structural basis of caspase-7 inhibition by XIAP | Q24290942 |
| Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain | Q24290943 | ||
| Structural basis for the inhibition of caspase-3 by XIAP | Q24290945 | ||
| TAK1 is a ubiquitin-dependent kinase of MKK and IKK | Q24291454 | ||
| IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition | Q24292370 | ||
| Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases | Q24294565 | ||
| Mechanism of XIAP-mediated inhibition of caspase-9 | Q24296916 | ||
| Distinct molecular mechanism for initiating TRAF6 signalling | Q24302174 | ||
| TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction | Q24312956 | ||
| X-linked IAP is a direct inhibitor of cell-death proteases | Q24318710 | ||
| Dimeric association and segmental variability in the structure of human CD4 | Q24324340 | ||
| XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway | Q24533501 | ||
| Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution | Q24561750 | ||
| A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors | Q24562976 | ||
| Upstream regulatory role for XIAP in receptor-mediated apoptosis | Q24563793 | ||
| Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family | Q24670396 | ||
| The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites | Q24673550 | ||
| Improved methods for building protein models in electron density maps and the location of errors in these models | Q26776980 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| Structural basis for self-association and receptor recognition of human TRAF2 | Q27617947 | ||
| Structural and biochemical basis of apoptotic activation by Smac/DIABLO | Q27626899 | ||
| Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain | Q27629143 | ||
| Structural basis of IAP recognition by Smac/DIABLO | Q27629148 | ||
| Structural basis for the autoinhibition of c-Abl tyrosine kinase | Q27640773 | ||
| SOLVE and RESOLVE: automated structure solution, density modification and model building | Q27860452 | ||
| ARP/wARP and molecular replacement | Q27860622 | ||
| Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition | Q28115131 | ||
| The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins | Q28117866 | ||
| Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins | Q28117928 | ||
| TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway | Q28140039 | ||
| Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain | Q28142613 | ||
| Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1 | Q28144306 | ||
| A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha | Q28187818 | ||
| X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling | Q28189393 | ||
| Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction | Q28271470 | ||
| TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains | Q28278500 | ||
| An alternate conformation and a third metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr protein phosphatase | Q28486667 | ||
| The TGF beta activated kinase TAK1 regulates vascular development in vivo | Q28507785 | ||
| Structural Basis of Caspase Inhibition by XIAP | Q29011600 | ||
| Ubiquitin signalling in the NF-kappaB pathway | Q29616322 | ||
| Thermodynamics of binding to SH3 domains: the energetic impact of polyproline II (PII) helix formation | Q30164016 | ||
| Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells | Q33181379 | ||
| Role of TAK1 and TAB1 in BMP signaling in early Xenopus development | Q33888315 | ||
| TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development | Q33963111 | ||
| Targeting XIAP for the treatment of malignancy | Q33991803 | ||
| Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance | Q34132152 | ||
| XIAP: apoptotic brake and promising therapeutic target. | Q34303728 | ||
| IAPs, RINGs and ubiquitylation | Q36085601 | ||
| Regulators of apoptosis: suitable targets for immune therapy of cancer | Q36111911 | ||
| An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif | Q36686481 | ||
| Selective activation of JNK1 is necessary for the anti-apoptotic activity of hILP. | Q37376986 | ||
| TAK1-binding protein 1 is a pseudophosphatase. | Q38739200 | ||
| A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo | Q38837520 | ||
| Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac | Q39389950 | ||
| XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders. | Q40303646 | ||
| Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity | Q40422412 | ||
| Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells. | Q40444073 | ||
| Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells. | Q40459513 | ||
| Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics | Q40513940 | ||
| Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis | Q40602863 | ||
| Multiple activation mechanisms of p38alpha mitogen-activated protein kinase | Q45090963 | ||
| The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2. | Q46200610 | ||
| Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death | Q46725238 | ||
| Structural basis for the interaction of TAK1 kinase with its activating protein TAB1. | Q46804739 | ||
| Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis | Q47670151 | ||
| XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland. | Q52085775 | ||
| Regulation of smooth muscle phosphatase-II by divalent cations | Q67914813 | ||
| Determination of diffusion coefficients of biological macromolecules by dynamic light scattering | Q72784686 | ||
| Improving biosensor analysis | Q73170565 | ||
| Expression of TAK1, a mediator of TGF-β and BMP signaling, during mouse embryonic development | Q73309188 | ||
| xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells | Q73442318 | ||
| P433 | issue | 5 | |
| P921 | main subject | cell biology | Q7141 |
| NF-κB | Q411114 | ||
| P304 | page(s) | 689-702 | |
| P577 | publication date | 2007-06-01 | |
| P1433 | published in | Molecular Cell | Q3319468 |
| P1476 | title | XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization | |
| P478 | volume | 26 |
| Q38837520 | A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo |
| Q36040441 | A functional microRNA library screen reveals miR-410 as a novel anti-apoptotic regulator of cholangiocarcinoma. |
| Q36495236 | A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy |
| Q33526462 | A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway |
| Q33971047 | A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-κB activation and apoptosis in P19 cells. |
| Q33788930 | A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases. |
| Q24321222 | ARTS and Siah collaborate in a pathway for XIAP degradation |
| Q34185807 | Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells |
| Q33618500 | Analysis of inhibitor of apoptosis protein family expression during mammary gland development |
| Q88689268 | Anti-Inflammatory Peptide Attenuates Edema and Promotes BMP-2-Induced Bone Formation in Spine Fusion |
| Q38924245 | Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer. |
| Q37448134 | Assembling the building blocks: structure and function of inhibitor of apoptosis proteins |
| Q24310283 | Asymmetric recruitment of cIAPs by TRAF2 |
| Q36800176 | Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice |
| Q27658192 | Backbone and side-chain 1H, 13C and 15N assignments of the ubiquitin-associated domain of human X-linked inhibitor of apoptosis protein |
| Q37801468 | Bone Morphogenetic Proteins: A critical review |
| Q36954601 | Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation |
| Q91173432 | Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer |
| Q37310195 | Caspase-independent cell death: leaving the set without the final cut. |
| Q36067026 | Cell-permeable intrinsic cellular inhibitors of apoptosis protect and rescue intestinal epithelial cells from radiation-induced cell death |
| Q39112125 | Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry |
| Q47236264 | Computational and experimental investigation of DNA repair protein photolyase interactions with low molecular weight drugs. |
| Q90428040 | Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach |
| Q27647264 | Crystal Structure of the BIR1 Domain of XIAP in Two Crystal Forms |
| Q27660497 | Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation |
| Q37995692 | DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. |
| Q37745528 | Deletion Of XIAP reduces the severity of acute pancreatitis via regulation of cell death and nuclear factor-κB activity |
| Q37621033 | Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling |
| Q37181412 | Disruption of TAB1/p38α interaction using a cell-permeable peptide limits myocardial ischemia/reperfusion injury |
| Q39926297 | Diverse functions within the IAP family |
| Q39887647 | Effect of bone morphogenetic protein-6 on macrophages |
| Q41452284 | Effects of neurotrophin receptor-mediated MAGE homology on proliferation and odontoblastic differentiation of mouse dental pulp cells |
| Q92447210 | Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma |
| Q39681016 | Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells |
| Q41363923 | Employing XIAP to enhance the duration of antigen expression and immunity against an avian influenza H5 DNA vaccine |
| Q64914219 | Engineering of Human Corneal Endothelial Cells In Vitro. |
| Q28538867 | Evodiamine synergizes with doxorubicin in the treatment of chemoresistant human breast cancer without inhibiting P-glycoprotein |
| Q38271582 | Evolutionary roots of arginase expression and regulation |
| Q37974461 | Exploiting inhibitor of apoptosis proteins as therapeutic targets in hematological malignancies |
| Q35657414 | Fas death receptor signalling: roles of Bid and XIAP. |
| Q89510331 | From Genetic Alterations to Tumor Microenvironment: The Ariadne's String in Pancreatic Cancer |
| Q39591089 | Further insights into the mechanism of hypoxia-induced NFκB. [corrected]. |
| Q34190534 | Host Insect Inhibitor-of-Apoptosis SfIAP Functionally Replaces Baculovirus IAP but Is Differentially Regulated by Its N-Terminal Leader |
| Q34161533 | IAP inhibitors enhance co-stimulation to promote tumor immunity |
| Q37209606 | IAP proteins as targets for drug development in oncology |
| Q33638504 | IAP regulation of metastasis |
| Q37302745 | IAP-targeted therapies for cancer |
| Q39927741 | IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis |
| Q26866467 | IAPs: a central element in the NF-κB activating signaling pathway |
| Q24292870 | IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer |
| Q37148694 | IAPs: what's in a name? |
| Q34117399 | Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1. |
| Q38974466 | Impact of inhibitor of apoptosis proteins on immune modulation and inflammation |
| Q86500575 | Induction of a type I interferon signature in normal human monocytes by gadolinium-based contrast agents: comparison of linear and macrocyclic agents |
| Q89722704 | Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis |
| Q28590362 | Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice |
| Q54123125 | Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP. |
| Q38184343 | Inhibitor of Apoptosis (IAP) proteins in hematological malignancies: molecular mechanisms and therapeutic opportunities |
| Q42949488 | Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy |
| Q26824586 | Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation |
| Q37293572 | Inhibitor of apoptosis proteins in eukaryotic evolution and development: a model of thematic conservation |
| Q37336610 | Inhibitor of apoptosis proteins in hematological malignancies |
| Q47607136 | Inhibitors of apoptosis: clinical implications in cancer. |
| Q42372892 | Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3 |
| Q38866722 | Key regulators of apoptosis execution as biomarker candidates in melanoma |
| Q37637552 | Knockdown of both p120 catenin and Kaiso promotes expansion of human corneal endothelial monolayers via RhoA-ROCK-noncanonical BMP-NFκB pathway |
| Q55022368 | Lambertianic Acid Sensitizes Non-Small Cell Lung Cancers to TRAIL-Induced Apoptosis via Inhibition of XIAP/NF-κB and Activation of Caspases and Death Receptor 4. |
| Q49704722 | Legionella effector AnkX interacts with host nuclear protein PLEKHN1. |
| Q42569633 | Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling |
| Q94545250 | Molecular and Functional Characterization of Inhibitor of Apoptosis Proteins (IAP, BIRP) in Echinococcus granulosus |
| Q36918115 | Molecular basis of NF-κB signaling |
| Q37785354 | Molecular cell death platforms and assemblies |
| Q37020757 | Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis. |
| Q37680800 | Molecules that modulate Apaf-1 activity |
| Q38003578 | NAIPs: building an innate immune barrier against bacterial pathogens. NAIPs function as sensors that initiate innate immunity by detection of bacterial proteins in the host cell cytosol |
| Q26822516 | NF-κB, the first quarter-century: remarkable progress and outstanding questions |
| Q27697656 | NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway |
| Q42632400 | Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B. |
| Q42113128 | Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death |
| Q39096576 | Post-Translational Modifications of the TAK1-TAB Complex. |
| Q37702716 | Preclinical assesement of survivin and XIAP as prognostic biomarkers and therapeutic targets in gastroenteropancreatic neuroendocrine neoplasia |
| Q92824343 | Profiling of human lymphocytes reveals a specific network of protein kinases modulated by endurance training status |
| Q64101583 | Prognostic Value of XIAP Level in Patients with Various Cancers: A Systematic Review and Meta-Analysis |
| Q37284619 | Prognostic significance of XIAP and NF-κB expression in esophageal carcinoma with postoperative radiotherapy |
| Q42336467 | Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein |
| Q37679203 | Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs) |
| Q38087851 | Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists |
| Q27683623 | Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase |
| Q38921103 | S-nitrosylation of XIAP at Cys 213 of BIR2 domain impairs XIAP's anti-caspase 3 activity and anti-apoptotic function |
| Q37140171 | S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease |
| Q37277788 | Sex differences in XIAP cleavage after traumatic brain injury in the rat. |
| Q26864204 | Small-molecule SMAC mimetics as new cancer therapeutics |
| Q47114434 | Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP. |
| Q41456346 | Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection |
| Q64118080 | Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1 |
| Q94545199 | Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex |
| Q35414780 | Survivin and IAP proteins in cell-death mechanisms |
| Q47101674 | Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas |
| Q38040025 | TAK1, more than just innate immunity |
| Q36981023 | TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling |
| Q61809001 | Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment |
| Q38973682 | The Gβ5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma |
| Q37512362 | The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress |
| Q35964123 | The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice |
| Q47279342 | The evolution of BIR domain and its containing proteins |
| Q34345519 | The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. |
| Q64259310 | Third BIR domain of XIAP binds to both Cu(II) and Cu(I) in multiple sites and with diverse affinities characterized at atomic resolution |
| Q34242492 | Using flow cytometry to screen patients for X-linked lymphoproliferative disease due to SAP deficiency and XIAP deficiency |
| Q37012399 | X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis |
| Q38239689 | X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy. |
| Q37372003 | X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression |
| Q38367445 | X-linked inhibitor of apoptosis protein deficiency: more than an X-linked lymphoproliferative syndrome |
| Q36751784 | X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity. |
| Q27690253 | X-linked lymphoproliferative syndromes: brothers or distant cousins? |
| Q30354484 | XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell |
| Q39869165 | XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation |
| Q38099047 | XIAP antisense therapy with AEG 35156 in acute myeloid leukemia |
| Q37546803 | XIAP as a ubiquitin ligase in cellular signaling |
| Q34545370 | XIAP impairs Smac release from the mitochondria during apoptosis. |
| Q37101906 | XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling. |
| Q37321233 | XIAP mediates NOD signaling via interaction with RIP2 |
| Q27318530 | XIAP regulates cytosol-specific innate immunity to Listeria infection |
| Q47558714 | XIAP regulation by MNK links MAPK and NFκB signaling to determine an aggressive breast cancer phenotype. |
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